Gene Symbol | Ovol2 |
Entrez Gene ID | 296201 |
Full Name | ovo-like zinc finger 2 |
Synonyms | Zfp339 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ovol2 cDNA ORF clone
Gene Symbol | Ovol2 |
Entrez Gene ID | 296201 |
Full Name | ovo-like zinc finger 2 |
Synonyms | Zfp339 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001106519.1 | NP_001099989.1 | transcription factor Ovo-like 2 |
XM_006235124.3 | XP_006235186.1 | transcription factor Ovo-like 2 isoform X1 |
Homo sapiens (human) | OVOL2 | NP_067043.2 |
LOC699284 | XP_001087751.2 | |
Mus musculus (house mouse) | Ovol2 | NP_081200.2 |
Gallus gallus (chicken) | OVOL2 | XP_415018.3 |
Xenopus tropicalis (tropical clawed frog) | ovol2 | NP_001004998.1 |
Canis lupus familiaris (dog) | OVOL2 | XP_542876.2 |
Rattus norvegicus (Norway rat) | Ovol2 | NP_001099989.1 |
Danio rerio (zebrafish) | si:dkey-17e16.13 | XP_003200887.1 |
Pan troglodytes (chimpanzee) | OVOL2 | XP_001137624.2 |
Bos taurus (cattle) | OVOL2 | NP_001192936.1 |
OVOL2 antagonizes TGF-? signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis.
Wu RS, Hong JJ, Wu JF, Yan S, Wu D, Liu N, Liu QF, Wu QW, Xie YY, Liu YJ, Zheng ZZ, Chan EC, Zhang ZM, Li BA
Oncotarget8(24)39401-39416(2017 Jun)
Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells.
Lee B, Villarreal-Ponce A, Fallahi M, Ovadia J, Sun P, Yu QC, Ito S, Sinha S, Nie Q, Dai X
Developmental cell29(1)47-58(2014 Apr)
Mammary morphogenesis and regeneration require the inhibition of EMT at terminal end buds by Ovol2 transcriptional repressor.
Watanabe K, Villarreal-Ponce A, Sun P, Salmans ML, Fallahi M, Andersen B, Dai X
Developmental cell29(1)59-74(2014 Apr)
Ovol2 suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing c-Myc and Notch1.
Wells J, Lee B, Cai AQ, Karapetyan A, Lee WJ, Rugg E, Sinha S, Nie Q, Dai X
The Journal of biological chemistry284(42)29125-35(2009 Oct)
Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice.
Unezaki S, Horai R, Sudo K, Iwakura Y, Ito S
Genes to cells : devoted to molecular & cellular mechanisms12(6)773-85(2007 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Ovol2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ovol2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa01528 | |
Clone ID Related Accession (Same CDS sequence) | NM_001106519.1 | |
Accession Version | NM_001106519.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 726bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | transcription factor Ovo-like 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474026.2. On or before Oct 4, 2007 this sequence version replaced XM_001054248.1, XM_230639.4. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02642718, SAMN02642719 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAGCCTGG GCTGTCTGCT CCGCGACCCC CCCGAAGACT GCCGCAGCGA CGGTGGCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001099989.1 |
CDS | 69..794 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001106519.1 |
1 | ATGAGCCTGG GCTGTCTGCT CCGCGACCCC CCCGAAGACT GCCGCAGCGA CGGTGGCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa26449 | |
Clone ID Related Accession (Same CDS sequence) | XM_006235124.3 | |
Accession Version | XM_006235124.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | transcription factor Ovo-like 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006235124.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCCAAAG TCTTTCTGGT GAAGAGGAGG AGCCCGGGAG CCTCTGTCCG CAGCTGGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006235186.1 |
CDS | 1266..2090 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006235124.3 |
1 | ATGCCCAAAG TCTTTCTGGT GAAGAGGAGG AGCCCGGGAG CCTCTGTCCG CAGCTGGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
OVOL2 antagonizes TGF-? signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis. |
Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells. |
Mammary morphogenesis and regeneration require the inhibition of EMT at terminal end buds by Ovol2 transcriptional repressor. |
Ovol2 suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing c-Myc and Notch1. |
Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice. |