Herpud1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Herpud1
Entrez Gene ID	85430
Full Name	homocysteine inducible ER protein with ubiquitin like domain 1
Synonyms	Sup
General protein information	Preferred Names homocysteine inducible ER protein with ubiquitin like domain 1 Names homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 19 Map Location: 19p13
Summary	human homolog is a membrane protein that is induced by stress and may be involved in the cellular survival response to stress [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_053523.1	NP_445975.1	homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
XM_006255133.3	XP_006255195.2	homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Herpud1	NP_071726.1
	HERPUD1	XP_001095112.2
Bos taurus (cattle)	HERPUD1	NP_001095735.1
Canis lupus familiaris (dog)	HERPUD1	XP_851041.1
Rattus norvegicus (Norway rat)	Herpud1	NP_445975.1
Homo sapiens (human)	HERPUD1	NP_055500.1
Pan troglodytes (chimpanzee)	HERPUD1	XP_001141795.2
Gallus gallus (chicken)	HERPUD1	XP_414010.3
Danio rerio (zebrafish)	herpud1	NP_001020708.1
Xenopus tropicalis (tropical clawed frog)	herpud1	NP_998846.1

Gene Ontology
Bibliography

Related articles in PubMed

Increased expression of HERPUD1 involves in neuronal apoptosis after intracerebral hemorrhage.
Ding W, Chen R, Wu C, Chen W, Zhang H, Fan X, Wang H, Ji Y, Xie L, Ning X, Shen L
Brain research bulletin12840-47(2017 Jan)

New endoplasmic reticulum stress regulator, Gipie, regulates the survival of vascular smooth muscle cells and the neointima formation after vascular injury.
Noda T, Maeda K, Hayano S, Asai N, Enomoto A, Takahashi M, Murohara T
Arteriosclerosis, thrombosis, and vascular biology35(5)1246-53(2015 May)

Identification of ERAD components essential for dislocation of the null Hong Kong variant of ?-1-antitrypsin (NHK).
Zhong Y, Shen H, Wang Y, Yang Y, Yang P, Fang S
Biochemical and biophysical research communications458(2)424-8(2015 Mar)

Induction of Herpud1 expression by ER stress is regulated by Nrf1.
Ho DV, Chan JY
FEBS letters589(5)615-20(2015 Feb)

SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic ?-cells.
Tiwari A, Schuiki I, Zhang L, Allister EM, Wheeler MB, Volchuk A
Journal of cell science126(Pt 9)1962-8(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results showed that expression of HERPUD1 was increased around the hematoma, which indicated that HERPUD1 might involve in the physiological and pathological process during intracerebral hemorrhage; suggested that HERPUD1 was involved in neuronal apoptosis following intracerebral hemorrhage.
Title: Increased expression of HERPUD1 involves in neuronal apoptosis after intracerebral hemorrhage.

Endoplasmic reticulum stress regulator regulates the survival of vascular smooth cells and neointima formation.
Title: New endoplasmic reticulum stress regulator, Gipie, regulates the survival of vascular smooth muscle cells and the neointima formation after vascular injury.

Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress
Title: Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress.

The following Herpud1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Herpud1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09795	NM_053523.1 Latest version!	Rattus norvegicus homocysteine inducible ER protein with ubiquitin like domain 1 (Herpud1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa59498	XM_006255133.3 Latest version!	Rattus norvegicus homocysteine inducible ER protein with ubiquitin like domain 1 (Herpud1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Herpud1 ( NM_053523.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445975.1 Rattus norvegicus homocysteine inducible ER protein with ubiquitin like domain 1 (Herpud1), mRNA.

Price & Availability↑

CloneID	ORa09795
Clone ID Related Accession (Same CDS sequence)	NM_053523.1
Accession Version	NM_053523.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1176bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB033771.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB033771.1, BC061849.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCCCG AGCCACAGCC CGAGCCGGTC ACGCTGCTGG TGAAGAGCCC CAATCAGCGC 
CACCGCGACT TGGAGCTGAG TGGCGACCGC GGTTGGAGTG TGAGTCGCCT CAAGGCCCAC 
CTGAGCCGAG TCTACCCCGA ACGCCCGCGC CCAGAGGACC AGAGGTTAAT TTATTCTGGG 
AAGCTGCTGT TGGATCACCA ATGTCTCCAA GACTTGCTTC CAAAGCAGGA AAAGCGACAT 
GTTTTGCACC TCGTGTGCAA TGTGAGGAGT CCCTCAAAAA AGCCAGAAGC CAGCACAAAG 
GGTGCTGAGT CCACAGAGCA GCCGGACAAC ACTAGTCAGG CACAGTATCC TGGGGATTCC 
TCAAGCGATG GCTTACGGGA AAGGGAAGTC CTTCGGAACC TTCCTCCCTC TGGATGGGAG 
AACGTCTCTA GGCCTGAAGC CGTCCAGCAG ACTTTCCAAG GCCTCGGGCC CGGCTTCTCT 
GGCTACACCA CCTACGGGTG GCTGCAGCTC TCCTGGTTCC AGCAGATCTA TGCAAGACAG 
TACTACATGC AATACTTGGC TGCCACTGCT GCTTCAGGAG CTTTTGGCCC TACACCAAGT 
GCACAAGAAA TACCTGTGGT CTCTACACCG GCTCCCGCCC CTATACACAA CCAGTTTCCG 
GCAGAAAACC AGCCGGCCAA TCAGAATGCA GCCGCTCAAG CGGTTGTTAA TCCCGGAGCC 
AATCAGAACT TGCGGATGAA TGCACAAGGC GGCCCTCTGG TGGAAGAAGA TGATGAGATA 
AACCGAGACT GGTTGGATTG GACCTACTCA GCAGCGACAT TTTCCGTTTT CCTCAGCATT 
CTTTACTTCT ACTCCTCCCT GAGCAGATTC CTCATGGTCA TGGGCGCCAC CGTAGTCATG 
TACCTGCACC ACGTCGGGTG GTTTCCATTC AGACAGAGGC CAGTTCAGAA CTTCCCAGAT 
GACGGTCCCC CTCAGGAAGC TGCCAACCAG GACCCCAACA ATAACCTCCA GGGAGGTTTG 
GACCCTGAAA TGGAAGACCC CAACCGCCTC CCCGTAGGCC GTGAAGTGCT GGACCCTGAG 
CATACCAGCC CCTCGTTCAT GAGCACAGCA TGGCTAGTCT TCAAGACTTT CTTTGCCTCT 
CTTCTTCCGG AAGGCCCACC AGCCCTAGCA AACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445975.1
CDS	92..1267
Translation	MEPEPQPEPVTLLVKSPNQRHRDLELSGDRGWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLQDLLPKQEKRHVLHLVCNVRSPSKKPEASTKGAESTEQPDNTSQAQYPGDSSSDGLREREVLRNLPPSGWENVSRPEAVQQTFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFGPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQEAANQDPNNNLQGGLDPEMEDPNRLPVGREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN

Target ORF information:

RefSeq Version	NM_053523.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus homocysteine inducible ER protein with ubiquitin like domain 1 (Herpud1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053523.1

ORF Insert Sequence:

ATGGAGCCCG AGCCACAGCC CGAGCCGGTC ACGCTGCTGG TGAAGAGCCC CAATCAGCGC 
CACCGCGACT TGGAGCTGAG TGGCGACCGC GGTTGGAGTG TGAGTCGCCT CAAGGCCCAC 
CTGAGCCGAG TCTACCCCGA ACGCCCGCGC CCAGAGGACC AGAGGTTAAT TTATTCTGGG 
AAGCTGCTGT TGGATCACCA ATGTCTCCAA GACTTGCTTC CAAAGCAGGA AAAGCGACAT 
GTTTTGCACC TCGTGTGCAA TGTGAGGAGT CCCTCAAAAA AGCCAGAAGC CAGCACAAAG 
GGTGCTGAGT CCACAGAGCA GCCGGACAAC ACTAGTCAGG CACAGTATCC TGGGGATTCC 
TCAAGCGATG GCTTACGGGA AAGGGAAGTC CTTCGGAACC TTCCTCCCTC TGGATGGGAG 
AACGTCTCTA GGCCTGAAGC CGTCCAGCAG ACTTTCCAAG GCCTCGGGCC CGGCTTCTCT 
GGCTACACCA CCTACGGGTG GCTGCAGCTC TCCTGGTTCC AGCAGATCTA TGCAAGACAG 
TACTACATGC AATACTTGGC TGCCACTGCT GCTTCAGGAG CTTTTGGCCC TACACCAAGT 
GCACAAGAAA TACCTGTGGT CTCTACACCG GCTCCCGCCC CTATACACAA CCAGTTTCCG 
GCAGAAAACC AGCCGGCCAA TCAGAATGCA GCCGCTCAAG CGGTTGTTAA TCCCGGAGCC 
AATCAGAACT TGCGGATGAA TGCACAAGGC GGCCCTCTGG TGGAAGAAGA TGATGAGATA 
AACCGAGACT GGTTGGATTG GACCTACTCA GCAGCGACAT TTTCCGTTTT CCTCAGCATT 
CTTTACTTCT ACTCCTCCCT GAGCAGATTC CTCATGGTCA TGGGCGCCAC CGTAGTCATG 
TACCTGCACC ACGTCGGGTG GTTTCCATTC AGACAGAGGC CAGTTCAGAA CTTCCCAGAT 
GACGGTCCCC CTCAGGAAGC TGCCAACCAG GACCCCAACA ATAACCTCCA GGGAGGTTTG 
GACCCTGAAA TGGAAGACCC CAACCGCCTC CCCGTAGGCC GTGAAGTGCT GGACCCTGAG 
CATACCAGCC CCTCGTTCAT GAGCACAGCA TGGCTAGTCT TCAAGACTTT CTTTGCCTCT 
CTTCTTCCGG AAGGCCCACC AGCCCTAGCA AACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Herpud1 ( XM_006255133.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006255195.2 Rattus norvegicus homocysteine inducible ER protein with ubiquitin like domain 1 (Herpud1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa59498
Clone ID Related Accession (Same CDS sequence)	XM_006255133.3
Accession Version	XM_006255133.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1173bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005118.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255133.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCCG AGCCACAGCC CGAGCCGGTC ACGCTGCTGG TGAAGAGCCC CAATCAGCGC 
CACCGCGACT TGGAGCTGAG TGGCGACCGC GGTTGGAGTG TGAGTCGCCT CAAGGCCCAC 
CTGAGCCGAG TCTACCCCGA ACGCCCGCGC CCAGAGGACC AGAGGTTAAT TTATTCTGGG 
AAGCTGCTGT TGGATCACCA ATGTCTCCAA GACTTGCTTC CAAAGGAAAA GCGACATGTT 
TTGCACCTCG TGTGCAATGT GAGGAGTCCC TCAAAAAAGC CAGAAGCCAG CACAAAGGGT 
GCTGAGTCCA CAGAGCAGCC GGACAACACT AGTCAGGCAC AGTATCCTGG GGATTCCTCA 
AGCGATGGCT TACGGGAAAG GGAAGTCCTT CGGAACCTTC CTCCCTCTGG ATGGGAGAAC 
GTCTCTAGGC CTGAAGCCGT CCAGCAGACT TTCCAAGGCC TCGGGCCCGG CTTCTCTGGC 
TACACCACCT ACGGGTGGCT GCAGCTCTCC TGGTTCCAGC AGATCTATGC AAGACAGTAC 
TACATGCAAT ACTTGGCTGC CACTGCTGCT TCAGGAGCTT TTGGCCCTAC ACCAAGTGCA 
CAAGAAATAC CTGTGGTCTC TACACCGGCT CCCGCCCCTA TACACAACCA GTTTCCGGCA 
GAAAACCAGC CGGCCAATCA GAATGCAGCC GCTCAAGCGG TTGTTAATCC CGGAGCCAAT 
CAGAACTTGC GGATGAATGC ACAAGGCGGC CCTCTGGTGG AAGAAGATGA TGAGATAAAC 
CGAGACTGGT TGGATTGGAC CTACTCAGCA GCGACATTTT CCGTTTTCCT CAGCATTCTT 
TACTTCTACT CCTCCCTGAG CAGATTCCTC ATGGTCATGG GCGCCACCGT AGTCATGTAC 
CTGCACCACG TCGGGTGGTT TCCATTCAGA CAGAGGCCAG TTCAGAACTT CCCAGATGAC 
GGTCCCCCTC AGGAAGCTGC CAACCAGGAC CCCAACAATA ACCTCCAGGG AGGTTTGGAC 
CCTGAAATGG AAGACCCCAA CCGCCTCCCC GTAGGCCGTG AAGTGCTGGA CCCTGAGCAT 
ACCAGCCCCT CGTTCATGAG CACAGCATGG CTAGTCTTCA AGACTTTCTT TGCCTCTCTT 
CTTCCGGAAG GCCCACCAGC CCTAGCAAAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006255195.2
CDS	278..1450
Translation	MEPEPQPEPVTLLVKSPNQRHRDLELSGDRGWSVSRLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLQDLLPKEKRHVLHLVCNVRSPSKKPEASTKGAESTEQPDNTSQAQYPGDSSSDGLREREVLRNLPPSGWENVSRPEAVQQTFQGLGPGFSGYTTYGWLQLSWFQQIYARQYYMQYLAATAASGAFGPTPSAQEIPVVSTPAPAPIHNQFPAENQPANQNAAAQAVVNPGANQNLRMNAQGGPLVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRQRPVQNFPDDGPPQEAANQDPNNNLQGGLDPEMEDPNRLPVGREVLDPEHTSPSFMSTAWLVFKTFFASLLPEGPPALAN

Target ORF information:

RefSeq Version	XM_006255133.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus homocysteine inducible ER protein with ubiquitin like domain 1 (Herpud1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006255133.3

ORF Insert Sequence:

ATGGAGCCCG AGCCACAGCC CGAGCCGGTC ACGCTGCTGG TGAAGAGCCC CAATCAGCGC 
CACCGCGACT TGGAGCTGAG TGGCGACCGC GGTTGGAGTG TGAGTCGCCT CAAGGCCCAC 
CTGAGCCGAG TCTACCCCGA ACGCCCGCGC CCAGAGGACC AGAGGTTAAT TTATTCTGGG 
AAGCTGCTGT TGGATCACCA ATGTCTCCAA GACTTGCTTC CAAAGGAAAA GCGACATGTT 
TTGCACCTCG TGTGCAATGT GAGGAGTCCC TCAAAAAAGC CAGAAGCCAG CACAAAGGGT 
GCTGAGTCCA CAGAGCAGCC GGACAACACT AGTCAGGCAC AGTATCCTGG GGATTCCTCA 
AGCGATGGCT TACGGGAAAG GGAAGTCCTT CGGAACCTTC CTCCCTCTGG ATGGGAGAAC 
GTCTCTAGGC CTGAAGCCGT CCAGCAGACT TTCCAAGGCC TCGGGCCCGG CTTCTCTGGC 
TACACCACCT ACGGGTGGCT GCAGCTCTCC TGGTTCCAGC AGATCTATGC AAGACAGTAC 
TACATGCAAT ACTTGGCTGC CACTGCTGCT TCAGGAGCTT TTGGCCCTAC ACCAAGTGCA 
CAAGAAATAC CTGTGGTCTC TACACCGGCT CCCGCCCCTA TACACAACCA GTTTCCGGCA 
GAAAACCAGC CGGCCAATCA GAATGCAGCC GCTCAAGCGG TTGTTAATCC CGGAGCCAAT 
CAGAACTTGC GGATGAATGC ACAAGGCGGC CCTCTGGTGG AAGAAGATGA TGAGATAAAC 
CGAGACTGGT TGGATTGGAC CTACTCAGCA GCGACATTTT CCGTTTTCCT CAGCATTCTT 
TACTTCTACT CCTCCCTGAG CAGATTCCTC ATGGTCATGG GCGCCACCGT AGTCATGTAC 
CTGCACCACG TCGGGTGGTT TCCATTCAGA CAGAGGCCAG TTCAGAACTT CCCAGATGAC 
GGTCCCCCTC AGGAAGCTGC CAACCAGGAC CCCAACAATA ACCTCCAGGG AGGTTTGGAC 
CCTGAAATGG AAGACCCCAA CCGCCTCCCC GTAGGCCGTG AAGTGCTGGA CCCTGAGCAT 
ACCAGCCCCT CGTTCATGAG CACAGCATGG CTAGTCTTCA AGACTTTCTT TGCCTCTCTT 
CTTCCGGAAG GCCCACCAGC CCTAGCAAAC TGA