Gene Symbol | Alas |
Entrez Gene ID | 37815 |
Full Name | Aminolevulinate synthase |
Synonyms | ALAS,CG3017,Dmel\CG3017,alas |
General protein information |
|
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
ORF » Species Summary » Drosophila melanogaster » Alas cDNA ORF clone
Gene Symbol | Alas |
Entrez Gene ID | 37815 |
Full Name | Aminolevulinate synthase |
Synonyms | ALAS,CG3017,Dmel\CG3017,alas |
General protein information |
|
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_057933.5 | NP_477281.1 | aminolevulinate synthase |
Drosophila melanogaster (fruit fly) | Alas | NP_477281.1 |
Xenopus tropicalis (tropical clawed frog) | alas2 | NP_001006926.1 |
Canis lupus familiaris (dog) | ALAS2 | XP_548619.4 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003184 | XP_312882.5 |
Saccharomyces cerevisiae (baker's yeast) | HEM1 | NP_010518.1 |
Eremothecium gossypii | AGOS_ABL104C | NP_982843.1 |
Danio rerio (zebrafish) | alas2 | NP_571757.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06446 | XP_003717121.1 |
Bos taurus (cattle) | ALAS2 | NP_001030275.1 |
Rattus norvegicus (Norway rat) | Alas2 | NP_037329.1 |
Schizosaccharomyces pombe (fission yeast) | hem1 | NP_594388.1 |
Neurospora crassa | NCU06189 | XP_963001.2 |
Homo sapiens (human) | ALAS2 | NP_000023.2 |
Pan troglodytes (chimpanzee) | ALAS2 | XP_528998.2 |
ALAS2 | XP_002806298.1 | |
Mus musculus (house mouse) | Alas2 | NP_033783.1 |
Kluyveromyces lactis | KLLA0C15059g | XP_452875.1 |
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The results demonstrated that alas and CG33156 are indispensable for ecdysteroidogenesis.
Title: Deep sequencing of the prothoracic gland transcriptome reveals new players in insect ecdysteroidogenesis.
aminolevulinate synthase activity, which initiates heme biosynthesis in the mitochondrion, is needed for the formation of a dityrosine-based barrier that confers resistance to the internal hydrostatic pressure
Title: ?-Aminolevulinate synthase is required for apical transcellular barrier formation in the skin of the Drosophila larva.
Delta-ALA-D from D. melanogaster and M.musculus has a different profile of optimum pH and different sensitivity for diphenyl diselenide and lead, two inhibitors.
Title: Diphenyl diselenide [(PhSe)2] inhibits Drosophila melanogaster delta-aminolevulinate dehydratase (delta-ALA-D) gene transcription and enzyme activity.
The following Alas gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Alas cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OFa11085 | |
Clone ID Related Accession (Same CDS sequence) | NM_057933.5 | |
Accession Version | NM_057933.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1620bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | aminolevulinate synthase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_057933.4. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGCAGTGTC CGTTCTTGAA CCGCTTCACC GCCAGCTTCA TCCGCAACTA CGCGGAGACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_477281.1 |
CDS | 114..1733 |
Translation |
Target ORF information:
Target ORF information:
|
NM_057933.5 |
1 | ATGCAGTGTC CGTTCTTGAA CCGCTTCACC GCCAGCTTCA TCCGCAACTA CGCGGAGACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. |
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. |
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. |
The Release 5.1 annotation of Drosophila melanogaster heterochromatin. |
Combined evidence annotation of transposable elements in genome sequences. |