BPIFB6 cDNA ORF clone, Homo sapiens(human)
| Gene Symbol | BPIFB6 |
| Entrez Gene ID | 128859 |
| Full Name | BPI fold containing family B member 6 |
| Synonyms | BPIL3,LPLUNC6 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Disorder MIM: |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| XM_017027663.1 | XP_016883152.1 | BPI fold-containing family B member 6 isoform X1 |
| NM_174897.2 | NP_777557.1 | BPI fold-containing family B member 6 precursor |
| Pan troglodytes (chimpanzee) | BPIFB6 | XP_001154703.2 |
| Mus musculus (house mouse) | Bpifb6 | NP_955007.2 |
| Homo sapiens (human) | BPIFB6 | NP_777557.1 |
| Canis lupus familiaris (dog) | BPIFB6 | XP_852407.1 |
| BPIFB6 | XP_001106236.1 | |
| Bos taurus (cattle) | BPIFB6 | NP_001244142.1 |
| Rattus norvegicus (Norway rat) | Bpifb6 | NP_001101261.1 |
Related articles in PubMed
BPIFB6 Regulates Secretory Pathway Trafficking and Enterovirus Replication.
Morosky S, Lennemann NJ, Coyne CB
Journal of virology90(10)5098-107(2016 05)
Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily.
Bingle CD, Seal RL, Craven CJ
Biochemical Society transactions39(4)977-83(2011 Aug)
New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)
Phylogenetic and evolutionary analysis of the PLUNC gene family.
Bingle CD, LeClair EE, Havard S, Bingle L, Gillingham P, Craven CJ
Protein science : a publication of the Protein Society13(2)422-30(2004 Feb)
Three new human members of the lipid transfer/lipopolysaccharide binding protein family (LT/LBP).
Mulero JJ, Boyle BJ, Bradley S, Bright JM, Nelken ST, Ho TT, Mize NK, Childs JD, Ballinger DG, Ford JE, Rupp F
Immunogenetics54(5)293-300(2002 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
study reports on the cellular function of BPIFB6 in the regulation of secretory pathway trafficking and Golgi complex morphology; in addition, findings show that BPIFB6 functions as a positive regulator of enterovirus replication via its regulation of the secretory pathway
Title: BPIFB6 Regulates Secretory Pathway Trafficking and Enterovirus Replication.
Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.
BPIL3 maps to Chromosome 20q11; thus, these novel genes form a cluster with BPI and two other members of the LT/LBP gene family on the long arm of human Chr 20. AA sequence is reported.
Title: Three new human members of the lipid transfer/lipopolysaccharide binding protein family (LT/LBP).
The following BPIFB6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BPIFB6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu32030 | |
| Clone ID Related Accession (Same CDS sequence) | NM_174897.2 | |
| Accession Version | NM_174897.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Homo sapiens(human) | |
| Product | BPI fold-containing family B member 6 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF465767.1 and BC113122.1. On May 19, 2009 this sequence version replaced NM_174897.1. ##Evidence-Data-START## Transcript exon combination :: AF465767.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000349552.1/ ENSP00000344929.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## | |
1 | ATGCTGCGGA TCCTGTGCCT GGCACTCTGC AGCCTGCTGA CTGGCACGCG AGCTGACCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_777557.1 |
| CDS | 1..1362 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_174897.2 |
ORF Insert Sequence:
1 | ATGCTGCGGA TCCTGTGCCT GGCACTCTGC AGCCTGCTGA CTGGCACGCG AGCTGACCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu92916 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017027663.1 | |
| Accession Version | XM_017027663.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-05 | |
| Organism | Homo sapiens(human) | |
| Product | BPI fold-containing family B member 6 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## | |
1 | ATGCTGCGGA TCCTGTGCCT GGCACTCTGC AGCCTGCTGA CTGGCACGCG AGCTGACCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_016883152.1 |
| CDS | 1..1410 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017027663.1 |
ORF Insert Sequence:
1 | ATGCTGCGGA TCCTGTGCCT GGCACTCTGC AGCCTGCTGA CTGGCACGCG AGCTGACCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
BPIFB6 Regulates Secretory Pathway Trafficking and Enterovirus Replication. |
|
Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. |
|
New genetic associations detected in a host response study to hepatitis B vaccine. |
|
Phylogenetic and evolutionary analysis of the PLUNC gene family. |
|
Three new human members of the lipid transfer/lipopolysaccharide binding protein family (LT/LBP). |