×

NTRK1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol NTRK1
Entrez Gene ID 4914
Full Name neurotrophic receptor tyrosine kinase 1
Synonyms MTC,TRK,TRK1,TRKA,Trk-A,p140-TrkA
General protein information
Preferred Names

neurotrophic receptor tyrosine kinase 1

Names

high affinity nerve growth factor receptor
Oncogene TRK
TRK1-transforming tyrosine kinase protein
gp140trk
neurotrophic tyrosine kinase, receptor, type 1
tropomyosin-related kinase A
tyrosine kinase receptor A

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

1

1q23.1

Summary This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008].
Disorder MIM:

191315

Disorder Html: Insensitivity to pain, congenital, with anhidrosis, 256800 (3);

mRNA and Protein(s)

mRNA Protein Name
NM_001007792.1 NP_001007793.1 high affinity nerve growth factor receptor isoform 3
NM_001012331.1 NP_001012331.1 high affinity nerve growth factor receptor isoform 1 precursor
NM_002529.3 NP_002520.2 high affinity nerve growth factor receptor isoform 2 precursor



Xenopus tropicalis (tropical clawed frog) ntrk1 XP_002939035.1
Pan troglodytes (chimpanzee) NTRK1 XP_003308563.1
Mus musculus (house mouse) Ntrk1 NP_001028296.1
Macaca mulatta (rhesus monkey) NTRK1 XP_001114243.2
Canis lupus familiaris (dog) NTRK1 XP_851619.3
Rattus norvegicus (Norway rat) Ntrk1 NP_067600.1
Homo sapiens (human) NTRK1 NP_002520.2
Bos taurus (cattle) NTRK1 XP_002686012.2
Gallus gallus (chicken) NTRK1 NP_990709.1
Danio rerio (zebrafish) ntrk1 XP_697246.5


Related articles in PubMed

Paediatric and adult soft tissue sarcomas with NTRK1 gene fusions: a subset of spindle cell sarcomas unified by a prominent myopericytic/haemangiopericytic pattern.
Haller F, Knopf J, Ackermann A, Bieg M, Kleinheinz K, Schlesner M, Moskalev EA, Will R, Satir AA, Abdelmagid IE, Giedl J, Carbon R, Rompel O, Hartmann A, Wiemann S, Metzler M, Agaimy A
The Journal of pathology238(5)700-10(2016 Apr)

NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells.
Ruggeri P, Cappabianca L, Farina AR, Gneo L, Mackay AR
Cell death & disease7e2139(2016 Mar)

NTRK1 fusions for the therapeutic intervention of Korean patients with colon cancer.
Park DY, Choi C, Shin E, Lee JH, Kwon CH, Jo HJ, Kim HR, Kim HS, Oh N, Lee JS, Park OK, Park E, Park J, Shin JY, Kim JI, Seo JS, Park HD, Park J
Oncotarget7(7)8399-412(2016 02)

Knowledge-based analysis of functional impacts of mutations in microRNA seed regions.
Bhattacharya A, Cui Y
Journal of biosciences40(4)791-8(2015 Oct)

NGF Modulates trkANGFR/p75NTR in αSMA-Expressing Conjunctival Fibroblasts from Human Ocular Cicatricial Pemphigoid (OCP).
Micera A, Stampachiacchiere B, Di Zazzo A, Sgrulletta R, Cortes M, Normando EM, Lambiase A, Bonini S
PloS one10(11)e0142737(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NT3 upregulates cellular proliferation, extracellular matrix protein production, and collagen deposition in human aortic valve interstitial cells through the Trk-Akt-cyclin D1 cascade.
Title: Neurotrophin 3 upregulates proliferation and collagen production in human aortic valve interstitial cells: a potential role in aortic valve sclerosis.

ShcD binds to active Ret, TrkA, and TrkB neurotrophic factor receptors predominantly via its phosphotyrosine-binding (PTB) domain.
Title: Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.

NTRK1 gene fusion in spitzoid neoplasms results in tumors with Kamino bodies and were typically arranged in smaller nests with smaller predominantly spindle-shaped cells, occasionally forming rosettes.
Title: A Comparison of Morphologic and Molecular Features of BRAF, ALK, and NTRK1 Fusion Spitzoid Neoplasms.

A novel nonsense mutation and a known splice-site mutation were detected in NTRK1 in two siblings and were shown to be associated with congenital insensitivity to pain with anhidrosis.
Title: Identification of a novel nonsense mutation of the neurotrophic tyrosine kinase receptor type 1 gene in two siblings with congenital insensitivity to pain with anhidrosis.

This review highlights treatment options, including clinical trials for ROS1 rearrangement, RET fusions, NTRK1 fusions, MET exon skipping, BRAF mutations, and KRAS mutations.
Title: New Targets in Non-Small Cell Lung Cancer.

The following NTRK1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NTRK1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu22116 NM_001007792.1
Latest version!
Homo sapiens neurotrophic receptor tyrosine kinase 1 (NTRK1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$384.50-$538.30
$769.00
OHu22996 NM_001012331.1
Latest version!
Homo sapiens neurotrophic receptor tyrosine kinase 1 (NTRK1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu24045 NM_002529.3
Latest version!
Homo sapiens neurotrophic receptor tyrosine kinase 1 (NTRK1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$399.50-$559.30
$799.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu22116
Clone ID Related Accession (Same CDS sequence) NM_001007792.1
Accession Version NM_001007792.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2283bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-15
Organism Homo sapiens(Human)
Product high affinity nerve growth factor receptor isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL158169.17 and BC062580.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (3) utilizes alternate 5' exons and lacks an internal in-frame exon, compared to variant 2. Translation initiation occurs at an upstream AUG, resulting in a shorter isoform (3) with a unique N-terminus compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGAAGGAGG CCGCCCTCAT CTGCCTGGCA CCCTCTGTAC CCCCGATCTT GACGGTGAAG 
TCCTGGGACA CCATGCAGTT GCGGGCTGCT AGATCTCGGT GCACAAACTT GTTGGCAGCA
AGCTACATCG AGAACCAGCA GCATCTGCAG CATCTGGAGC TCCGTGATCT GAGGGGCCTG
GGGGAGCTGA GAAACCTCAC CATCGTGAAG AGTGGTCTCC GTTTCGTGGC GCCAGATGCC
TTCCATTTCA CTCCTCGGCT CAGTCGCCTG AATCTCTCCT TCAACGCTCT GGAGTCTCTC
TCCTGGAAAA CTGTGCAGGG CCTCTCCTTA CAGGAACTGG TCCTGTCGGG GAACCCTCTG
CACTGTTCTT GTGCCCTGCG CTGGCTACAG CGCTGGGAGG AGGAGGGACT GGGCGGAGTG
CCTGAACAGA AGCTGCAGTG TCATGGGCAA GGGCCCCTGG CCCACATGCC CAATGCCAGC
TGTGGTGTGC CCACGCTGAA GGTCCAGGTG CCCAATGCCT CGGTGGATGT GGGGGACGAC
GTGCTGCTGC GGTGCCAGGT GGAGGGGCGG GGCCTGGAGC AGGCCGGCTG GATCCTCACA
GAGCTGGAGC AGTCAGCCAC GGTGATGAAA TCTGGGGGTC TGCCATCCCT GGGGCTGACC
CTGGCCAATG TCACCAGTGA CCTCAACAGG AAGAACGTGA CGTGCTGGGC AGAGAACGAT
GTGGGCCGGG CAGAGGTCTC TGTTCAGGTC AACGTCTCCT TCCCGGCCAG TGTGCAGCTG
CACACGGCGG TGGAGATGCA CCACTGGTGC ATCCCCTTCT CTGTGGATGG GCAGCCGGCA
CCGTCTCTGC GCTGGCTCTT CAATGGCTCC GTGCTCAATG AGACCAGCTT CATCTTCACT
GAGTTCCTGG AGCCGGCAGC CAATGAGACC GTGCGGCACG GGTGTCTGCG CCTCAACCAG
CCCACCCACG TCAACAACGG CAACTACACG CTGCTGGCTG CCAACCCCTT CGGCCAGGCC
TCCGCCTCCA TCATGGCTGC CTTCATGGAC AACCCTTTCG AGTTCAACCC CGAGGACCCC
ATCCCTGACA CTAACAGCAC ATCTGGAGAC CCGGTGGAGA AGAAGGACGA AACACCTTTT
GGGGTCTCGG TGGCTGTGGG CCTGGCCGTC TTTGCCTGCC TCTTCCTTTC TACGCTGCTC
CTTGTGCTCA ACAAATGTGG ACGGAGAAAC AAGTTTGGGA TCAACCGCCC GGCTGTGCTG
GCTCCAGAGG ATGGGCTGGC CATGTCCCTG CATTTCATGA CATTGGGTGG CAGCTCCCTG
TCCCCCACCG AGGGCAAAGG CTCTGGGCTC CAAGGCCACA TCATCGAGAA CCCACAATAC
TTCAGTGATG CCTGTGTTCA CCACATCAAG CGCCGGGACA TCGTGCTCAA GTGGGAGCTG
GGGGAGGGCG CCTTTGGGAA GGTCTTCCTT GCTGAGTGCC ACAACCTCCT GCCTGAGCAG
GACAAGATGC TGGTGGCTGT CAAGGCACTG AAGGAGGCGT CCGAGAGTGC TCGGCAGGAC
TTCCAGCGTG AGGCTGAGCT GCTCACCATG CTGCAGCACC AGCACATCGT GCGCTTCTTC
GGCGTCTGCA CCGAGGGCCG CCCCCTGCTC ATGGTCTTTG AGTATATGCG GCACGGGGAC
CTCAACCGCT TCCTCCGATC CCATGGACCT GATGCCAAGC TGCTGGCTGG TGGGGAGGAT
GTGGCTCCAG GCCCCCTGGG TCTGGGGCAG CTGCTGGCCG TGGCTAGCCA GGTCGCTGCG
GGGATGGTGT ACCTGGCGGG TCTGCATTTT GTGCACCGGG ACCTGGCCAC ACGCAACTGT
CTAGTGGGCC AGGGACTGGT GGTCAAGATT GGTGATTTTG GCATGAGCAG GGATATCTAC
AGCACCGACT ATTACCGTGT GGGAGGCCGC ACCATGCTGC CCATTCGCTG GATGCCGCCC
GAGAGCATCC TGTACCGTAA GTTCACCACC GAGAGCGACG TGTGGAGCTT CGGCGTGGTG
CTCTGGGAGA TCTTCACCTA CGGCAAGCAG CCCTGGTACC AGCTCTCCAA CACGGAGGCA
ATCGACTGCA TCACGCAGGG ACGTGAGTTG GAGCGGCCAC GTGCCTGCCC ACCAGAGGTC
TACGCCATCA TGCGGGGCTG CTGGCAGCGG GAGCCCCAGC AACGCCACAG CATCAAGGAT
GTGCACGCCC GGCTGCAAGC CCTGGCCCAG GCACCTCCTG TCTACCTGGA TGTCCTGGGC
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001007793.1
CDS81..2363
Misc Feature(1)54..56
Misc Feature(2)264..440
Misc Feature(3)267..338
Misc Feature(4)339..407
Misc Feature(5)408..446
Misc Feature(6)441..566
Misc Feature(7)573..836
Misc Feature(8)831..836
Misc Feature(9)885..1127
Misc Feature(10)912..914
Misc Feature(11)order(987..989,1035..1040,1047..1049)
Misc Feature(12)1458..1460
Misc Feature(13)1482..2321
Misc Feature(14)1500..2315
Misc Feature(15)order(1518..1532,1542..1544,1596..1598,1602..1604,1737..1748,1755..1760,1920..1922,1932..1937,1941..1943,1974..1976,2028..2042,2067..2069,2169..2171)
Misc Feature(16)order(1518..1523,1527..1532,1542..1544,1596..1598,1602..1604,1737..1748,1755..1760,1932..1937,1941..1943,1974..1976)
Misc Feature(17)order(1920..1922,1932..1934,2028..2042,2067..2069,2169..2171)
Misc Feature(18)1971..2048
Misc Feature(19)1998..2000
Misc Feature(20)2010..2012
Misc Feature(21)2013..2015
Misc Feature(22)2241..2243
Misc Feature(23)2343..2345
Exon (1)1..89
Exon (2)90..202
Exon (3)203..277
Exon (4)278..349
Exon (5)350..418
Exon (6)419..564
Exon (7)565..707
Exon (8)708..840
Exon (9)841..1167
Exon (10)1168..1223
Exon (11)1224..1326
Exon (12)1327..1473
Exon (13)1474..1604
Exon (14)1605..1777
Exon (15)1778..2018
Exon (16)2019..2177
Exon (17)2178..2571
Translation

Target ORF information:

RefSeq Version NM_001007792.1
Organism Homo sapiens(Human)
Definition Homo sapiens neurotrophic receptor tyrosine kinase 1 (NTRK1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001007792.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGAAGGAGG CCGCCCTCAT CTGCCTGGCA CCCTCTGTAC CCCCGATCTT GACGGTGAAG 
TCCTGGGACA CCATGCAGTT GCGGGCTGCT AGATCTCGGT GCACAAACTT GTTGGCAGCA
AGCTACATCG AGAACCAGCA GCATCTGCAG CATCTGGAGC TCCGTGATCT GAGGGGCCTG
GGGGAGCTGA GAAACCTCAC CATCGTGAAG AGTGGTCTCC GTTTCGTGGC GCCAGATGCC
TTCCATTTCA CTCCTCGGCT CAGTCGCCTG AATCTCTCCT TCAACGCTCT GGAGTCTCTC
TCCTGGAAAA CTGTGCAGGG CCTCTCCTTA CAGGAACTGG TCCTGTCGGG GAACCCTCTG
CACTGTTCTT GTGCCCTGCG CTGGCTACAG CGCTGGGAGG AGGAGGGACT GGGCGGAGTG
CCTGAACAGA AGCTGCAGTG TCATGGGCAA GGGCCCCTGG CCCACATGCC CAATGCCAGC
TGTGGTGTGC CCACGCTGAA GGTCCAGGTG CCCAATGCCT CGGTGGATGT GGGGGACGAC
GTGCTGCTGC GGTGCCAGGT GGAGGGGCGG GGCCTGGAGC AGGCCGGCTG GATCCTCACA
GAGCTGGAGC AGTCAGCCAC GGTGATGAAA TCTGGGGGTC TGCCATCCCT GGGGCTGACC
CTGGCCAATG TCACCAGTGA CCTCAACAGG AAGAACGTGA CGTGCTGGGC AGAGAACGAT
GTGGGCCGGG CAGAGGTCTC TGTTCAGGTC AACGTCTCCT TCCCGGCCAG TGTGCAGCTG
CACACGGCGG TGGAGATGCA CCACTGGTGC ATCCCCTTCT CTGTGGATGG GCAGCCGGCA
CCGTCTCTGC GCTGGCTCTT CAATGGCTCC GTGCTCAATG AGACCAGCTT CATCTTCACT
GAGTTCCTGG AGCCGGCAGC CAATGAGACC GTGCGGCACG GGTGTCTGCG CCTCAACCAG
CCCACCCACG TCAACAACGG CAACTACACG CTGCTGGCTG CCAACCCCTT CGGCCAGGCC
TCCGCCTCCA TCATGGCTGC CTTCATGGAC AACCCTTTCG AGTTCAACCC CGAGGACCCC
ATCCCTGACA CTAACAGCAC ATCTGGAGAC CCGGTGGAGA AGAAGGACGA AACACCTTTT
GGGGTCTCGG TGGCTGTGGG CCTGGCCGTC TTTGCCTGCC TCTTCCTTTC TACGCTGCTC
CTTGTGCTCA ACAAATGTGG ACGGAGAAAC AAGTTTGGGA TCAACCGCCC GGCTGTGCTG
GCTCCAGAGG ATGGGCTGGC CATGTCCCTG CATTTCATGA CATTGGGTGG CAGCTCCCTG
TCCCCCACCG AGGGCAAAGG CTCTGGGCTC CAAGGCCACA TCATCGAGAA CCCACAATAC
TTCAGTGATG CCTGTGTTCA CCACATCAAG CGCCGGGACA TCGTGCTCAA GTGGGAGCTG
GGGGAGGGCG CCTTTGGGAA GGTCTTCCTT GCTGAGTGCC ACAACCTCCT GCCTGAGCAG
GACAAGATGC TGGTGGCTGT CAAGGCACTG AAGGAGGCGT CCGAGAGTGC TCGGCAGGAC
TTCCAGCGTG AGGCTGAGCT GCTCACCATG CTGCAGCACC AGCACATCGT GCGCTTCTTC
GGCGTCTGCA CCGAGGGCCG CCCCCTGCTC ATGGTCTTTG AGTATATGCG GCACGGGGAC
CTCAACCGCT TCCTCCGATC CCATGGACCT GATGCCAAGC TGCTGGCTGG TGGGGAGGAT
GTGGCTCCAG GCCCCCTGGG TCTGGGGCAG CTGCTGGCCG TGGCTAGCCA GGTCGCTGCG
GGGATGGTGT ACCTGGCGGG TCTGCATTTT GTGCACCGGG ACCTGGCCAC ACGCAACTGT
CTAGTGGGCC AGGGACTGGT GGTCAAGATT GGTGATTTTG GCATGAGCAG GGATATCTAC
AGCACCGACT ATTACCGTGT GGGAGGCCGC ACCATGCTGC CCATTCGCTG GATGCCGCCC
GAGAGCATCC TGTACCGTAA GTTCACCACC GAGAGCGACG TGTGGAGCTT CGGCGTGGTG
CTCTGGGAGA TCTTCACCTA CGGCAAGCAG CCCTGGTACC AGCTCTCCAA CACGGAGGCA
ATCGACTGCA TCACGCAGGG ACGTGAGTTG GAGCGGCCAC GTGCCTGCCC ACCAGAGGTC
TACGCCATCA TGCGGGGCTG CTGGCAGCGG GAGCCCCAGC AACGCCACAG CATCAAGGAT
GTGCACGCCC GGCTGCAAGC CCTGGCCCAG GCACCTCCTG TCTACCTGGA TGTCCTGGGC
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22996
Clone ID Related Accession (Same CDS sequence) NM_001012331.1
Accession Version NM_001012331.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2373bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-27
Organism Homo sapiens(Human)
Product high affinity nerve growth factor receptor isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M23102.1, BC062580.1 and BM685020.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) lacks an internal, in-frame exon, compared to variant 2, resulting in a shorter isoform (1) lacking an internal segment compared to isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M23102.1, SRR1660807.64084.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145544 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGCTGCGAG GCGGACGGCG CGGGCAGCTT GGCTGGCACA GCTGGGCTGC GGGGCCGGGC 
AGCCTGCTGG CTTGGCTGAT ACTGGCATCT GCGGGCGCCG CACCCTGCCC CGATGCCTGC
TGCCCCCACG GCTCCTCGGG ACTGCGATGC ACCCGGGATG GGGCCCTGGA TAGCCTCCAC
CACCTGCCCG GCGCAGAGAA CCTGACTGAG CTCTACATCG AGAACCAGCA GCATCTGCAG
CATCTGGAGC TCCGTGATCT GAGGGGCCTG GGGGAGCTGA GAAACCTCAC CATCGTGAAG
AGTGGTCTCC GTTTCGTGGC GCCAGATGCC TTCCATTTCA CTCCTCGGCT CAGTCGCCTG
AATCTCTCCT TCAACGCTCT GGAGTCTCTC TCCTGGAAAA CTGTGCAGGG CCTCTCCTTA
CAGGAACTGG TCCTGTCGGG GAACCCTCTG CACTGTTCTT GTGCCCTGCG CTGGCTACAG
CGCTGGGAGG AGGAGGGACT GGGCGGAGTG CCTGAACAGA AGCTGCAGTG TCATGGGCAA
GGGCCCCTGG CCCACATGCC CAATGCCAGC TGTGGTGTGC CCACGCTGAA GGTCCAGGTG
CCCAATGCCT CGGTGGATGT GGGGGACGAC GTGCTGCTGC GGTGCCAGGT GGAGGGGCGG
GGCCTGGAGC AGGCCGGCTG GATCCTCACA GAGCTGGAGC AGTCAGCCAC GGTGATGAAA
TCTGGGGGTC TGCCATCCCT GGGGCTGACC CTGGCCAATG TCACCAGTGA CCTCAACAGG
AAGAACGTGA CGTGCTGGGC AGAGAACGAT GTGGGCCGGG CAGAGGTCTC TGTTCAGGTC
AACGTCTCCT TCCCGGCCAG TGTGCAGCTG CACACGGCGG TGGAGATGCA CCACTGGTGC
ATCCCCTTCT CTGTGGATGG GCAGCCGGCA CCGTCTCTGC GCTGGCTCTT CAATGGCTCC
GTGCTCAATG AGACCAGCTT CATCTTCACT GAGTTCCTGG AGCCGGCAGC CAATGAGACC
GTGCGGCACG GGTGTCTGCG CCTCAACCAG CCCACCCACG TCAACAACGG CAACTACACG
CTGCTGGCTG CCAACCCCTT CGGCCAGGCC TCCGCCTCCA TCATGGCTGC CTTCATGGAC
AACCCTTTCG AGTTCAACCC CGAGGACCCC ATCCCTGACA CTAACAGCAC ATCTGGAGAC
CCGGTGGAGA AGAAGGACGA AACACCTTTT GGGGTCTCGG TGGCTGTGGG CCTGGCCGTC
TTTGCCTGCC TCTTCCTTTC TACGCTGCTC CTTGTGCTCA ACAAATGTGG ACGGAGAAAC
AAGTTTGGGA TCAACCGCCC GGCTGTGCTG GCTCCAGAGG ATGGGCTGGC CATGTCCCTG
CATTTCATGA CATTGGGTGG CAGCTCCCTG TCCCCCACCG AGGGCAAAGG CTCTGGGCTC
CAAGGCCACA TCATCGAGAA CCCACAATAC TTCAGTGATG CCTGTGTTCA CCACATCAAG
CGCCGGGACA TCGTGCTCAA GTGGGAGCTG GGGGAGGGCG CCTTTGGGAA GGTCTTCCTT
GCTGAGTGCC ACAACCTCCT GCCTGAGCAG GACAAGATGC TGGTGGCTGT CAAGGCACTG
AAGGAGGCGT CCGAGAGTGC TCGGCAGGAC TTCCAGCGTG AGGCTGAGCT GCTCACCATG
CTGCAGCACC AGCACATCGT GCGCTTCTTC GGCGTCTGCA CCGAGGGCCG CCCCCTGCTC
ATGGTCTTTG AGTATATGCG GCACGGGGAC CTCAACCGCT TCCTCCGATC CCATGGACCT
GATGCCAAGC TGCTGGCTGG TGGGGAGGAT GTGGCTCCAG GCCCCCTGGG TCTGGGGCAG
CTGCTGGCCG TGGCTAGCCA GGTCGCTGCG GGGATGGTGT ACCTGGCGGG TCTGCATTTT
GTGCACCGGG ACCTGGCCAC ACGCAACTGT CTAGTGGGCC AGGGACTGGT GGTCAAGATT
GGTGATTTTG GCATGAGCAG GGATATCTAC AGCACCGACT ATTACCGTGT GGGAGGCCGC
ACCATGCTGC CCATTCGCTG GATGCCGCCC GAGAGCATCC TGTACCGTAA GTTCACCACC
GAGAGCGACG TGTGGAGCTT CGGCGTGGTG CTCTGGGAGA TCTTCACCTA CGGCAAGCAG
CCCTGGTACC AGCTCTCCAA CACGGAGGCA ATCGACTGCA TCACGCAGGG ACGTGAGTTG
GAGCGGCCAC GTGCCTGCCC ACCAGAGGTC TACGCCATCA TGCGGGGCTG CTGGCAGCGG
GAGCCCCAGC AACGCCACAG CATCAAGGAT GTGCACGCCC GGCTGCAAGC CCTGGCCCAG
GCACCTCCTG TCTACCTGGA TGTCCTGGGC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001012331.1
CDS57..2429
Misc Feature(1)258..332
Misc Feature(2)324..395
Misc Feature(3)330..506
Misc Feature(4)333..404
Misc Feature(5)402..467
Misc Feature(6)405..473
Misc Feature(7)474..512
Misc Feature(8)507..632
Misc Feature(9)639..902
Misc Feature(10)897..902
Misc Feature(11)951..1193
Misc Feature(12)978..980
Misc Feature(13)order(1053..1055,1101..1106,1113..1115)
Misc Feature(14)1308..1355
Misc Feature(15)1443..1508
Misc Feature(16)1494..1496
Misc Feature(17)1524..1526
Misc Feature(18)1524..1526
Misc Feature(19)1524..1526
Misc Feature(20)1548..2387
Misc Feature(21)1566..2381
Misc Feature(22)order(1584..1598,1608..1610,1662..1664,1668..1670,1803..1814,1821..1826,1986..1988,1998..2003,2007..2009,2040..2042,2094..2108,2133..2135,2235..2237)
Misc Feature(23)order(1584..1589,1593..1598,1608..1610,1662..1664,1668..1670,1803..1814,1821..1826,1998..2003,2007..2009,2040..2042)
Misc Feature(24)order(1986..1988,1998..2000,2094..2108,2133..2135,2235..2237)
Misc Feature(25)2037..2114
Misc Feature(26)2064..2066
Misc Feature(27)2064..2066
Misc Feature(28)2076..2078
Misc Feature(29)2076..2078
Misc Feature(30)2079..2081
Misc Feature(31)2079..2081
Misc Feature(32)2307..2309
Misc Feature(33)2409..2411
Misc Feature(34)2409..2411
Misc Feature(35)2409..2411
Exon (1)1..268
Exon (2)269..343
Exon (3)344..415
Exon (4)416..484
Exon (5)485..630
Exon (6)631..773
Exon (7)774..906
Exon (8)907..1233
Exon (9)1234..1289
Exon (10)1290..1392
Exon (11)1393..1539
Exon (12)1540..1670
Exon (13)1671..1843
Exon (14)1844..2084
Exon (15)2085..2243
Exon (16)2244..2637
Translation

Target ORF information:

RefSeq Version NM_001012331.1
Organism Homo sapiens(Human)
Definition Homo sapiens neurotrophic receptor tyrosine kinase 1 (NTRK1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001012331.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGCTGCGAG GCGGACGGCG CGGGCAGCTT GGCTGGCACA GCTGGGCTGC GGGGCCGGGC 
AGCCTGCTGG CTTGGCTGAT ACTGGCATCT GCGGGCGCCG CACCCTGCCC CGATGCCTGC
TGCCCCCACG GCTCCTCGGG ACTGCGATGC ACCCGGGATG GGGCCCTGGA TAGCCTCCAC
CACCTGCCCG GCGCAGAGAA CCTGACTGAG CTCTACATCG AGAACCAGCA GCATCTGCAG
CATCTGGAGC TCCGTGATCT GAGGGGCCTG GGGGAGCTGA GAAACCTCAC CATCGTGAAG
AGTGGTCTCC GTTTCGTGGC GCCAGATGCC TTCCATTTCA CTCCTCGGCT CAGTCGCCTG
AATCTCTCCT TCAACGCTCT GGAGTCTCTC TCCTGGAAAA CTGTGCAGGG CCTCTCCTTA
CAGGAACTGG TCCTGTCGGG GAACCCTCTG CACTGTTCTT GTGCCCTGCG CTGGCTACAG
CGCTGGGAGG AGGAGGGACT GGGCGGAGTG CCTGAACAGA AGCTGCAGTG TCATGGGCAA
GGGCCCCTGG CCCACATGCC CAATGCCAGC TGTGGTGTGC CCACGCTGAA GGTCCAGGTG
CCCAATGCCT CGGTGGATGT GGGGGACGAC GTGCTGCTGC GGTGCCAGGT GGAGGGGCGG
GGCCTGGAGC AGGCCGGCTG GATCCTCACA GAGCTGGAGC AGTCAGCCAC GGTGATGAAA
TCTGGGGGTC TGCCATCCCT GGGGCTGACC CTGGCCAATG TCACCAGTGA CCTCAACAGG
AAGAACGTGA CGTGCTGGGC AGAGAACGAT GTGGGCCGGG CAGAGGTCTC TGTTCAGGTC
AACGTCTCCT TCCCGGCCAG TGTGCAGCTG CACACGGCGG TGGAGATGCA CCACTGGTGC
ATCCCCTTCT CTGTGGATGG GCAGCCGGCA CCGTCTCTGC GCTGGCTCTT CAATGGCTCC
GTGCTCAATG AGACCAGCTT CATCTTCACT GAGTTCCTGG AGCCGGCAGC CAATGAGACC
GTGCGGCACG GGTGTCTGCG CCTCAACCAG CCCACCCACG TCAACAACGG CAACTACACG
CTGCTGGCTG CCAACCCCTT CGGCCAGGCC TCCGCCTCCA TCATGGCTGC CTTCATGGAC
AACCCTTTCG AGTTCAACCC CGAGGACCCC ATCCCTGACA CTAACAGCAC ATCTGGAGAC
CCGGTGGAGA AGAAGGACGA AACACCTTTT GGGGTCTCGG TGGCTGTGGG CCTGGCCGTC
TTTGCCTGCC TCTTCCTTTC TACGCTGCTC CTTGTGCTCA ACAAATGTGG ACGGAGAAAC
AAGTTTGGGA TCAACCGCCC GGCTGTGCTG GCTCCAGAGG ATGGGCTGGC CATGTCCCTG
CATTTCATGA CATTGGGTGG CAGCTCCCTG TCCCCCACCG AGGGCAAAGG CTCTGGGCTC
CAAGGCCACA TCATCGAGAA CCCACAATAC TTCAGTGATG CCTGTGTTCA CCACATCAAG
CGCCGGGACA TCGTGCTCAA GTGGGAGCTG GGGGAGGGCG CCTTTGGGAA GGTCTTCCTT
GCTGAGTGCC ACAACCTCCT GCCTGAGCAG GACAAGATGC TGGTGGCTGT CAAGGCACTG
AAGGAGGCGT CCGAGAGTGC TCGGCAGGAC TTCCAGCGTG AGGCTGAGCT GCTCACCATG
CTGCAGCACC AGCACATCGT GCGCTTCTTC GGCGTCTGCA CCGAGGGCCG CCCCCTGCTC
ATGGTCTTTG AGTATATGCG GCACGGGGAC CTCAACCGCT TCCTCCGATC CCATGGACCT
GATGCCAAGC TGCTGGCTGG TGGGGAGGAT GTGGCTCCAG GCCCCCTGGG TCTGGGGCAG
CTGCTGGCCG TGGCTAGCCA GGTCGCTGCG GGGATGGTGT ACCTGGCGGG TCTGCATTTT
GTGCACCGGG ACCTGGCCAC ACGCAACTGT CTAGTGGGCC AGGGACTGGT GGTCAAGATT
GGTGATTTTG GCATGAGCAG GGATATCTAC AGCACCGACT ATTACCGTGT GGGAGGCCGC
ACCATGCTGC CCATTCGCTG GATGCCGCCC GAGAGCATCC TGTACCGTAA GTTCACCACC
GAGAGCGACG TGTGGAGCTT CGGCGTGGTG CTCTGGGAGA TCTTCACCTA CGGCAAGCAG
CCCTGGTACC AGCTCTCCAA CACGGAGGCA ATCGACTGCA TCACGCAGGG ACGTGAGTTG
GAGCGGCCAC GTGCCTGCCC ACCAGAGGTC TACGCCATCA TGCGGGGCTG CTGGCAGCGG
GAGCCCCAGC AACGCCACAG CATCAAGGAT GTGCACGCCC GGCTGCAAGC CCTGGCCCAG
GCACCTCCTG TCTACCTGGA TGTCCTGGGC TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24045
Clone ID Related Accession (Same CDS sequence) NM_002529.3
Accession Version NM_002529.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2391bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-27
Organism Homo sapiens(Human)
Product high affinity nerve growth factor receptor isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M23102.1, BC062580.1 and X06704.1. This sequence is a reference standard in the RefSeqGene project. On or before Feb 16, 2005 this sequence version replaced NM_001007204.1, NM_002529.2. Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC062580.1, AK312704.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2146411 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGCTGCGAG GCGGACGGCG CGGGCAGCTT GGCTGGCACA GCTGGGCTGC GGGGCCGGGC 
AGCCTGCTGG CTTGGCTGAT ACTGGCATCT GCGGGCGCCG CACCCTGCCC CGATGCCTGC
TGCCCCCACG GCTCCTCGGG ACTGCGATGC ACCCGGGATG GGGCCCTGGA TAGCCTCCAC
CACCTGCCCG GCGCAGAGAA CCTGACTGAG CTCTACATCG AGAACCAGCA GCATCTGCAG
CATCTGGAGC TCCGTGATCT GAGGGGCCTG GGGGAGCTGA GAAACCTCAC CATCGTGAAG
AGTGGTCTCC GTTTCGTGGC GCCAGATGCC TTCCATTTCA CTCCTCGGCT CAGTCGCCTG
AATCTCTCCT TCAACGCTCT GGAGTCTCTC TCCTGGAAAA CTGTGCAGGG CCTCTCCTTA
CAGGAACTGG TCCTGTCGGG GAACCCTCTG CACTGTTCTT GTGCCCTGCG CTGGCTACAG
CGCTGGGAGG AGGAGGGACT GGGCGGAGTG CCTGAACAGA AGCTGCAGTG TCATGGGCAA
GGGCCCCTGG CCCACATGCC CAATGCCAGC TGTGGTGTGC CCACGCTGAA GGTCCAGGTG
CCCAATGCCT CGGTGGATGT GGGGGACGAC GTGCTGCTGC GGTGCCAGGT GGAGGGGCGG
GGCCTGGAGC AGGCCGGCTG GATCCTCACA GAGCTGGAGC AGTCAGCCAC GGTGATGAAA
TCTGGGGGTC TGCCATCCCT GGGGCTGACC CTGGCCAATG TCACCAGTGA CCTCAACAGG
AAGAACGTGA CGTGCTGGGC AGAGAACGAT GTGGGCCGGG CAGAGGTCTC TGTTCAGGTC
AACGTCTCCT TCCCGGCCAG TGTGCAGCTG CACACGGCGG TGGAGATGCA CCACTGGTGC
ATCCCCTTCT CTGTGGATGG GCAGCCGGCA CCGTCTCTGC GCTGGCTCTT CAATGGCTCC
GTGCTCAATG AGACCAGCTT CATCTTCACT GAGTTCCTGG AGCCGGCAGC CAATGAGACC
GTGCGGCACG GGTGTCTGCG CCTCAACCAG CCCACCCACG TCAACAACGG CAACTACACG
CTGCTGGCTG CCAACCCCTT CGGCCAGGCC TCCGCCTCCA TCATGGCTGC CTTCATGGAC
AACCCTTTCG AGTTCAACCC CGAGGACCCC ATCCCTGTCT CCTTCTCGCC GGTGGACACT
AACAGCACAT CTGGAGACCC GGTGGAGAAG AAGGACGAAA CACCTTTTGG GGTCTCGGTG
GCTGTGGGCC TGGCCGTCTT TGCCTGCCTC TTCCTTTCTA CGCTGCTCCT TGTGCTCAAC
AAATGTGGAC GGAGAAACAA GTTTGGGATC AACCGCCCGG CTGTGCTGGC TCCAGAGGAT
GGGCTGGCCA TGTCCCTGCA TTTCATGACA TTGGGTGGCA GCTCCCTGTC CCCCACCGAG
GGCAAAGGCT CTGGGCTCCA AGGCCACATC ATCGAGAACC CACAATACTT CAGTGATGCC
TGTGTTCACC ACATCAAGCG CCGGGACATC GTGCTCAAGT GGGAGCTGGG GGAGGGCGCC
TTTGGGAAGG TCTTCCTTGC TGAGTGCCAC AACCTCCTGC CTGAGCAGGA CAAGATGCTG
GTGGCTGTCA AGGCACTGAA GGAGGCGTCC GAGAGTGCTC GGCAGGACTT CCAGCGTGAG
GCTGAGCTGC TCACCATGCT GCAGCACCAG CACATCGTGC GCTTCTTCGG CGTCTGCACC
GAGGGCCGCC CCCTGCTCAT GGTCTTTGAG TATATGCGGC ACGGGGACCT CAACCGCTTC
CTCCGATCCC ATGGACCTGA TGCCAAGCTG CTGGCTGGTG GGGAGGATGT GGCTCCAGGC
CCCCTGGGTC TGGGGCAGCT GCTGGCCGTG GCTAGCCAGG TCGCTGCGGG GATGGTGTAC
CTGGCGGGTC TGCATTTTGT GCACCGGGAC CTGGCCACAC GCAACTGTCT AGTGGGCCAG
GGACTGGTGG TCAAGATTGG TGATTTTGGC ATGAGCAGGG ATATCTACAG CACCGACTAT
TACCGTGTGG GAGGCCGCAC CATGCTGCCC ATTCGCTGGA TGCCGCCCGA GAGCATCCTG
TACCGTAAGT TCACCACCGA GAGCGACGTG TGGAGCTTCG GCGTGGTGCT CTGGGAGATC
TTCACCTACG GCAAGCAGCC CTGGTACCAG CTCTCCAACA CGGAGGCAAT CGACTGCATC
ACGCAGGGAC GTGAGTTGGA GCGGCCACGT GCCTGCCCAC CAGAGGTCTA CGCCATCATG
CGGGGCTGCT GGCAGCGGGA GCCCCAGCAA CGCCACAGCA TCAAGGATGT GCACGCCCGG
CTGCAAGCCC TGGCCCAGGC ACCTCCTGTC TACCTGGATG TCCTGGGCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002520.2
CDS57..2447
Misc Feature(1)258..332
Misc Feature(2)324..395
Misc Feature(3)330..506
Misc Feature(4)333..404
Misc Feature(5)402..467
Misc Feature(6)405..473
Misc Feature(7)474..512
Misc Feature(8)507..632
Misc Feature(9)639..902
Misc Feature(10)897..902
Misc Feature(11)951..1193
Misc Feature(12)978..980
Misc Feature(13)order(1053..1055,1101..1106,1113..1115)
Misc Feature(14)1248..1253
Misc Feature(15)1326..1373
Misc Feature(16)1461..1526
Misc Feature(17)1512..1514
Misc Feature(18)1524..1526
Misc Feature(19)1542..1544
Misc Feature(20)1542..1544
Misc Feature(21)1566..2405
Misc Feature(22)1584..2399
Misc Feature(23)order(1602..1616,1626..1628,1680..1682,1686..1688,1821..1832,1839..1844,2004..2006,2016..2021,2025..2027,2058..2060,2112..2126,2151..2153,2253..2255)
Misc Feature(24)order(1602..1607,1611..1616,1626..1628,1680..1682,1686..1688,1821..1832,1839..1844,2016..2021,2025..2027,2058..2060)
Misc Feature(25)order(2004..2006,2016..2018,2112..2126,2151..2153,2253..2255)
Misc Feature(26)2055..2132
Misc Feature(27)2064..2066
Misc Feature(28)2076..2078
Misc Feature(29)2079..2081
Misc Feature(30)2082..2084
Misc Feature(31)2094..2096
Misc Feature(32)2097..2099
Misc Feature(33)2307..2309
Misc Feature(34)2409..2411
Misc Feature(35)2427..2429
Misc Feature(36)2427..2429
Exon (1)1..268
Exon (2)269..343
Exon (3)344..415
Exon (4)416..484
Exon (5)485..630
Exon (6)631..773
Exon (7)774..906
Exon (8)907..1233
Exon (9)1234..1251
Exon (10)1252..1307
Exon (11)1308..1410
Exon (12)1411..1557
Exon (13)1558..1688
Exon (14)1689..1861
Exon (15)1862..2102
Exon (16)2103..2261
Exon (17)2262..2655
Translation

Target ORF information:

RefSeq Version NM_002529.3
Organism Homo sapiens(Human)
Definition Homo sapiens neurotrophic receptor tyrosine kinase 1 (NTRK1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002529.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGCTGCGAG GCGGACGGCG CGGGCAGCTT GGCTGGCACA GCTGGGCTGC GGGGCCGGGC 
AGCCTGCTGG CTTGGCTGAT ACTGGCATCT GCGGGCGCCG CACCCTGCCC CGATGCCTGC
TGCCCCCACG GCTCCTCGGG ACTGCGATGC ACCCGGGATG GGGCCCTGGA TAGCCTCCAC
CACCTGCCCG GCGCAGAGAA CCTGACTGAG CTCTACATCG AGAACCAGCA GCATCTGCAG
CATCTGGAGC TCCGTGATCT GAGGGGCCTG GGGGAGCTGA GAAACCTCAC CATCGTGAAG
AGTGGTCTCC GTTTCGTGGC GCCAGATGCC TTCCATTTCA CTCCTCGGCT CAGTCGCCTG
AATCTCTCCT TCAACGCTCT GGAGTCTCTC TCCTGGAAAA CTGTGCAGGG CCTCTCCTTA
CAGGAACTGG TCCTGTCGGG GAACCCTCTG CACTGTTCTT GTGCCCTGCG CTGGCTACAG
CGCTGGGAGG AGGAGGGACT GGGCGGAGTG CCTGAACAGA AGCTGCAGTG TCATGGGCAA
GGGCCCCTGG CCCACATGCC CAATGCCAGC TGTGGTGTGC CCACGCTGAA GGTCCAGGTG
CCCAATGCCT CGGTGGATGT GGGGGACGAC GTGCTGCTGC GGTGCCAGGT GGAGGGGCGG
GGCCTGGAGC AGGCCGGCTG GATCCTCACA GAGCTGGAGC AGTCAGCCAC GGTGATGAAA
TCTGGGGGTC TGCCATCCCT GGGGCTGACC CTGGCCAATG TCACCAGTGA CCTCAACAGG
AAGAACGTGA CGTGCTGGGC AGAGAACGAT GTGGGCCGGG CAGAGGTCTC TGTTCAGGTC
AACGTCTCCT TCCCGGCCAG TGTGCAGCTG CACACGGCGG TGGAGATGCA CCACTGGTGC
ATCCCCTTCT CTGTGGATGG GCAGCCGGCA CCGTCTCTGC GCTGGCTCTT CAATGGCTCC
GTGCTCAATG AGACCAGCTT CATCTTCACT GAGTTCCTGG AGCCGGCAGC CAATGAGACC
GTGCGGCACG GGTGTCTGCG CCTCAACCAG CCCACCCACG TCAACAACGG CAACTACACG
CTGCTGGCTG CCAACCCCTT CGGCCAGGCC TCCGCCTCCA TCATGGCTGC CTTCATGGAC
AACCCTTTCG AGTTCAACCC CGAGGACCCC ATCCCTGTCT CCTTCTCGCC GGTGGACACT
AACAGCACAT CTGGAGACCC GGTGGAGAAG AAGGACGAAA CACCTTTTGG GGTCTCGGTG
GCTGTGGGCC TGGCCGTCTT TGCCTGCCTC TTCCTTTCTA CGCTGCTCCT TGTGCTCAAC
AAATGTGGAC GGAGAAACAA GTTTGGGATC AACCGCCCGG CTGTGCTGGC TCCAGAGGAT
GGGCTGGCCA TGTCCCTGCA TTTCATGACA TTGGGTGGCA GCTCCCTGTC CCCCACCGAG
GGCAAAGGCT CTGGGCTCCA AGGCCACATC ATCGAGAACC CACAATACTT CAGTGATGCC
TGTGTTCACC ACATCAAGCG CCGGGACATC GTGCTCAAGT GGGAGCTGGG GGAGGGCGCC
TTTGGGAAGG TCTTCCTTGC TGAGTGCCAC AACCTCCTGC CTGAGCAGGA CAAGATGCTG
GTGGCTGTCA AGGCACTGAA GGAGGCGTCC GAGAGTGCTC GGCAGGACTT CCAGCGTGAG
GCTGAGCTGC TCACCATGCT GCAGCACCAG CACATCGTGC GCTTCTTCGG CGTCTGCACC
GAGGGCCGCC CCCTGCTCAT GGTCTTTGAG TATATGCGGC ACGGGGACCT CAACCGCTTC
CTCCGATCCC ATGGACCTGA TGCCAAGCTG CTGGCTGGTG GGGAGGATGT GGCTCCAGGC
CCCCTGGGTC TGGGGCAGCT GCTGGCCGTG GCTAGCCAGG TCGCTGCGGG GATGGTGTAC
CTGGCGGGTC TGCATTTTGT GCACCGGGAC CTGGCCACAC GCAACTGTCT AGTGGGCCAG
GGACTGGTGG TCAAGATTGG TGATTTTGGC ATGAGCAGGG ATATCTACAG CACCGACTAT
TACCGTGTGG GAGGCCGCAC CATGCTGCCC ATTCGCTGGA TGCCGCCCGA GAGCATCCTG
TACCGTAAGT TCACCACCGA GAGCGACGTG TGGAGCTTCG GCGTGGTGCT CTGGGAGATC
TTCACCTACG GCAAGCAGCC CTGGTACCAG CTCTCCAACA CGGAGGCAAT CGACTGCATC
ACGCAGGGAC GTGAGTTGGA GCGGCCACGT GCCTGCCCAC CAGAGGTCTA CGCCATCATG
CGGGGCTGCT GGCAGCGGGA GCCCCAGCAA CGCCACAGCA TCAAGGATGT GCACGCCCGG
CTGCAAGCCC TGGCCCAGGC ACCTCCTGTC TACCTGGATG TCCTGGGCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Paediatric and adult soft tissue sarcomas with NTRK1 gene fusions: a subset of spindle cell sarcomas unified by a prominent myopericytic/haemangiopericytic pattern.
The Journal of pathology238(5)700-10(2016 Apr)
Haller F,Knopf J,Ackermann A,Bieg M,Kleinheinz K,Schlesner M,Moskalev EA,Will R,Satir AA,Abdelmagid IE,Giedl J,Carbon R,Rompel O,Hartmann A,Wiemann S,Metzler M,Agaimy A


book

NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells.
Cell death & disease7e2139(2016 Mar)
Ruggeri P,Cappabianca L,Farina AR,Gneo L,Mackay AR


book

NTRK1 fusions for the therapeutic intervention of Korean patients with colon cancer.
Oncotarget7(7)8399-412(2016 02)
Park DY,Choi C,Shin E,Lee JH,Kwon CH,Jo HJ,Kim HR,Kim HS,Oh N,Lee JS,Park OK,Park E,Park J,Shin JY,Kim JI,Seo JS,Park HD,Park J


book

Knowledge-based analysis of functional impacts of mutations in microRNA seed regions.
Journal of biosciences40(4)791-8(2015 Oct)
Bhattacharya A,Cui Y


book

NGF Modulates trkANGFR/p75NTR in αSMA-Expressing Conjunctival Fibroblasts from Human Ocular Cicatricial Pemphigoid (OCP).
PloS one10(11)e0142737(2015)
Micera A,Stampachiacchiere B,Di Zazzo A,Sgrulletta R,Cortes M,Normando EM,Lambiase A,Bonini S


 
*
*
*
*