OSTC cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	OSTC
Entrez Gene ID	58505
Full Name	oligosaccharyltransferase complex non-catalytic subunit
Synonyms	DC2
General protein information	Preferred Names oligosaccharyltransferase complex non-catalytic subunit Names oligosaccharyltransferase complex subunit OSTC hydrophobic protein HSF-28 oligosaccharyltransferase complex subunit (non-catalytic)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q25

mRNA and Protein(s)

mRNA	Protein	Name
NM_001267817.1	NP_001254746.1	oligosaccharyltransferase complex subunit OSTC isoform 2
NM_021227.4	NP_067050.1	oligosaccharyltransferase complex subunit OSTC isoform 1
NM_021227.3	NP_067050.1	oligosaccharyltransferase complex subunit OSTC isoform 1
NM_001267818.2	NP_001254747.1	oligosaccharyltransferase complex subunit OSTC isoform 3
NM_001267818.1	NP_001254747.1	oligosaccharyltransferase complex subunit OSTC isoform 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	OSTC	NP_067050.1
Drosophila melanogaster (fruit fly)	CG9662	NP_608772.3
Pan troglodytes (chimpanzee)	OSTC	XP_003950440.1
Mus musculus (house mouse)	Ostc	NP_079785.1
Gallus gallus (chicken)	OSTC	NP_001006442.1
Danio rerio (zebrafish)	ostc	NP_956563.1
Bos taurus (cattle)	OSTC	NP_001070560.1
Rattus norvegicus (Norway rat)	Ostc	NP_001102036.1
Arabidopsis thaliana (thale cress)	AT4G29870	NP_194716.1
Oryza sativa (rice)	Os02g0315400	NP_001046663.1
Xenopus tropicalis (tropical clawed frog)	ostc	NP_001016656.1
	LOC715641	XP_001105949.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008475	XP_316970.3
Arabidopsis thaliana (thale cress)	AT2G19340	NP_849987.1

Gene Ontology
Bibliography

Related articles in PubMed

DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.
Shrimal S, Cherepanova NA, Gilmore R
The Journal of cell biology216(11)3625-3638(2017 Nov)

Heat shock induces expression of OSTC/DC2, a?novel subunit of oligosaccharyltransferase, in?vitro and in?vivo.
Chen CM, Tseng CN, Cho JJ, Lee YZ, Kao CL, Cheng YB, Hong YR, Cho CL
The Kaohsiung journal of medical sciences30(5)219-23(2014 May)

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J Jr, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP
Human molecular genetics19(12)2497-506(2010 Jun)

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.
Wang AG, Yoon SY, Oh JH, Jeon YJ, Kim M, Kim JM, Byun SS, Yang JO, Kim JH, Kim DG, Yeom YI, Yoo HS, Kim YS, Kim NS
Biochemical and biophysical research communications345(3)1022-32(2006 Jul)

Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.
Shibatani T, David LL, McCormack AL, Frueh K, Skach WR
Biochemistry44(16)5982-92(2005 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase STT3A and the endoplasmic reticulum translocon.
Title: DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.

These results suggest that the upregulation of OSTC/DC2, a novel component of the oligosaccharyltransferase complex, is part of the mammalian heat shock response.
Title: Heat shock induces expression of OSTC/DC2, a?novel subunit of oligosaccharyltransferase, in?vitro and in?vivo.

Observational study of gene-disease association. (HuGE Navigator)
Title: A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.

The following OSTC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OSTC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00713	NM_001267818.2 Latest version!	Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu01234	NM_021227.4 Latest version!	Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu00880	NM_001267817.1 Latest version!	Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu01234	NM_021227.3	Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu00713	NM_001267818.1	Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OSTC ( NM_001267818.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254747.1 Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu00713
Clone ID Related Accession (Same CDS sequence)	NM_001267818.2 , NM_001267818.1
Accession Version	NM_001267818.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	oligosaccharyltransferase complex subunit OSTC isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC107071.3, CN430159.1, AF343342.1 and BM994257.1. On May 31, 2019 this sequence version replaced NM_001267818.1. Transcript Variant: This variant (3) contains an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) is longer and has a distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CN430159.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACTT TGTACCGTGT CCCGTTCTTA GTGCTCGAAT GTCCCAACCT GAAGCTGAAG 
AAGCCGCCCT GGTTGCACAT GCCGTCGGCC ATGACTGTGT ATGCTCTGGT GGTGGTGTCT 
TACTTCCTCA TCACCGGAGG AATAATTTAT GATGTTATTG TTGAACCTCC AAGTGTCGGT 
TCTATGACTG ATGAACATGG GCATCAGAGG CCAGTAGCTT TCTTGGCCTA CAGAGTAAAT 
GGACAATATA TTATGGAAGG ACTTGCATCC AGCTTCCTAT TTACAATGGG AGGTTTAGGT 
TTCATAATCC TGGACCGATC GAATGCACCA AATATCCCAA AACTCAATAG ATTCCTTCTT 
CTGTTCATTG GATTCGTCTG TGTCCTATTG AGTTTTTTCA TGGCTAGAGT ATTCATGAGA 
ATGAAACTGC CACGGAGTCT CGCTCTGTTG CCCAGGCTGG AGTGCAGTGG CGTGATCTCG 
GCTCACTACA AACTCTGCCT CCCAGGGGCT ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254747.1
CDS	58..573
Translation	METLYRVPFLVLECPNLKLKKPPWLHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPRSLALLPRLECSGVISAHYKLCLPGAI

Target ORF information:

RefSeq Version	NM_001267818.2
Organism	Homo sapiens(human)
Definition	Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267818.2

ORF Insert Sequence:

ATGGAGACTT TGTACCGTGT CCCGTTCTTA GTGCTCGAAT GTCCCAACCT GAAGCTGAAG 
AAGCCGCCCT GGTTGCACAT GCCGTCGGCC ATGACTGTGT ATGCTCTGGT GGTGGTGTCT 
TACTTCCTCA TCACCGGAGG AATAATTTAT GATGTTATTG TTGAACCTCC AAGTGTCGGT 
TCTATGACTG ATGAACATGG GCATCAGAGG CCAGTAGCTT TCTTGGCCTA CAGAGTAAAT 
GGACAATATA TTATGGAAGG ACTTGCATCC AGCTTCCTAT TTACAATGGG AGGTTTAGGT 
TTCATAATCC TGGACCGATC GAATGCACCA AATATCCCAA AACTCAATAG ATTCCTTCTT 
CTGTTCATTG GATTCGTCTG TGTCCTATTG AGTTTTTTCA TGGCTAGAGT ATTCATGAGA 
ATGAAACTGC CACGGAGTCT CGCTCTGTTG CCCAGGCTGG AGTGCAGTGG CGTGATCTCG 
GCTCACTACA AACTCTGCCT CCCAGGGGCT ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OSTC ( NM_001267818.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254747.1 Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu00713
Clone ID Related Accession (Same CDS sequence)	NM_001267818.2 , NM_001267818.1
Accession Version	NM_001267818.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-14
Organism	Homo sapiens(human)
Product	oligosaccharyltransferase complex subunit OSTC isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC107071.3, CN430159.1, AF343342.1 and BM994257.1. Transcript Variant: This variant (3) contains an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) is longer and has a distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CN430159.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACTT TGTACCGTGT CCCGTTCTTA GTGCTCGAAT GTCCCAACCT GAAGCTGAAG 
AAGCCGCCCT GGTTGCACAT GCCGTCGGCC ATGACTGTGT ATGCTCTGGT GGTGGTGTCT 
TACTTCCTCA TCACCGGAGG AATAATTTAT GATGTTATTG TTGAACCTCC AAGTGTCGGT 
TCTATGACTG ATGAACATGG GCATCAGAGG CCAGTAGCTT TCTTGGCCTA CAGAGTAAAT 
GGACAATATA TTATGGAAGG ACTTGCATCC AGCTTCCTAT TTACAATGGG AGGTTTAGGT 
TTCATAATCC TGGACCGATC GAATGCACCA AATATCCCAA AACTCAATAG ATTCCTTCTT 
CTGTTCATTG GATTCGTCTG TGTCCTATTG AGTTTTTTCA TGGCTAGAGT ATTCATGAGA 
ATGAAACTGC CACGGAGTCT CGCTCTGTTG CCCAGGCTGG AGTGCAGTGG CGTGATCTCG 
GCTCACTACA AACTCTGCCT CCCAGGGGCT ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254747.1
CDS	72..587
Translation	METLYRVPFLVLECPNLKLKKPPWLHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPRSLALLPRLECSGVISAHYKLCLPGAI

Target ORF information:

RefSeq Version	NM_001267818.1
Organism	Homo sapiens(human)
Definition	Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267818.1

ORF Insert Sequence:

ATGGAGACTT TGTACCGTGT CCCGTTCTTA GTGCTCGAAT GTCCCAACCT GAAGCTGAAG 
AAGCCGCCCT GGTTGCACAT GCCGTCGGCC ATGACTGTGT ATGCTCTGGT GGTGGTGTCT 
TACTTCCTCA TCACCGGAGG AATAATTTAT GATGTTATTG TTGAACCTCC AAGTGTCGGT 
TCTATGACTG ATGAACATGG GCATCAGAGG CCAGTAGCTT TCTTGGCCTA CAGAGTAAAT 
GGACAATATA TTATGGAAGG ACTTGCATCC AGCTTCCTAT TTACAATGGG AGGTTTAGGT 
TTCATAATCC TGGACCGATC GAATGCACCA AATATCCCAA AACTCAATAG ATTCCTTCTT 
CTGTTCATTG GATTCGTCTG TGTCCTATTG AGTTTTTTCA TGGCTAGAGT ATTCATGAGA 
ATGAAACTGC CACGGAGTCT CGCTCTGTTG CCCAGGCTGG AGTGCAGTGG CGTGATCTCG 
GCTCACTACA AACTCTGCCT CCCAGGGGCT ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OSTC ( NM_021227.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_067050.1 Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu01234
Clone ID Related Accession (Same CDS sequence)	NM_021227.4 , NM_021227.3
Accession Version	NM_021227.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	oligosaccharyltransferase complex subunit OSTC isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC054857.1 and BM994257.1. On Nov 23, 2018 this sequence version replaced NM_021227.3. Transcript Variant: This variant (1) encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.454590.1, SRR5189661.43308.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000361564.9/ ENSP00000354676.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGACTT TGTACCGTGT CCCGTTCTTA GTGCTCGAAT GTCCCAACCT GAAGCTGAAG 
AAGCCGCCCT GGTTGCACAT GCCGTCGGCC ATGACTGTGT ATGCTCTGGT GGTGGTGTCT 
TACTTCCTCA TCACCGGAGG AATAATTTAT GATGTTATTG TTGAACCTCC AAGTGTCGGT 
TCTATGACTG ATGAACATGG GCATCAGAGG CCAGTAGCTT TCTTGGCCTA CAGAGTAAAT 
GGACAATATA TTATGGAAGG ACTTGCATCC AGCTTCCTAT TTACAATGGG AGGTTTAGGT 
TTCATAATCC TGGACCGATC GAATGCACCA AATATCCCAA AACTCAATAG ATTCCTTCTT 
CTGTTCATTG GATTCGTCTG TGTCCTATTG AGTTTTTTCA TGGCTAGAGT ATTCATGAGA 
ATGAAACTGC CGGGCTATCT GATGGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067050.1
CDS	58..507
Translation	METLYRVPFLVLECPNLKLKKPPWLHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG

Target ORF information:

RefSeq Version	NM_021227.4
Organism	Homo sapiens(human)
Definition	Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021227.4

ORF Insert Sequence:

ATGGAGACTT TGTACCGTGT CCCGTTCTTA GTGCTCGAAT GTCCCAACCT GAAGCTGAAG 
AAGCCGCCCT GGTTGCACAT GCCGTCGGCC ATGACTGTGT ATGCTCTGGT GGTGGTGTCT 
TACTTCCTCA TCACCGGAGG AATAATTTAT GATGTTATTG TTGAACCTCC AAGTGTCGGT 
TCTATGACTG ATGAACATGG GCATCAGAGG CCAGTAGCTT TCTTGGCCTA CAGAGTAAAT 
GGACAATATA TTATGGAAGG ACTTGCATCC AGCTTCCTAT TTACAATGGG AGGTTTAGGT 
TTCATAATCC TGGACCGATC GAATGCACCA AATATCCCAA AACTCAATAG ATTCCTTCTT 
CTGTTCATTG GATTCGTCTG TGTCCTATTG AGTTTTTTCA TGGCTAGAGT ATTCATGAGA 
ATGAAACTGC CGGGCTATCT GATGGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OSTC ( NM_021227.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_067050.1 Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu01234
Clone ID Related Accession (Same CDS sequence)	NM_021227.4 , NM_021227.3
Accession Version	NM_021227.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-29
Organism	Homo sapiens(human)
Product	oligosaccharyltransferase complex subunit OSTC isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC107071.3, BC054857.1 and BM994257.1. On Jun 22, 2012 this sequence version replaced NM_021227.2. Transcript Variant: This variant (1) encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.132844.1, SRR1163655.187195.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACTT TGTACCGTGT CCCGTTCTTA GTGCTCGAAT GTCCCAACCT GAAGCTGAAG 
AAGCCGCCCT GGTTGCACAT GCCGTCGGCC ATGACTGTGT ATGCTCTGGT GGTGGTGTCT 
TACTTCCTCA TCACCGGAGG AATAATTTAT GATGTTATTG TTGAACCTCC AAGTGTCGGT 
TCTATGACTG ATGAACATGG GCATCAGAGG CCAGTAGCTT TCTTGGCCTA CAGAGTAAAT 
GGACAATATA TTATGGAAGG ACTTGCATCC AGCTTCCTAT TTACAATGGG AGGTTTAGGT 
TTCATAATCC TGGACCGATC GAATGCACCA AATATCCCAA AACTCAATAG ATTCCTTCTT 
CTGTTCATTG GATTCGTCTG TGTCCTATTG AGTTTTTTCA TGGCTAGAGT ATTCATGAGA 
ATGAAACTGC CGGGCTATCT GATGGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067050.1
CDS	72..521
Translation	METLYRVPFLVLECPNLKLKKPPWLHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRVNGQYIMEGLASSFLFTMGGLGFIILDRSNAPNIPKLNRFLLLFIGFVCVLLSFFMARVFMRMKLPGYLMG

Target ORF information:

RefSeq Version	NM_021227.3
Organism	Homo sapiens(human)
Definition	Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021227.3

ORF Insert Sequence:

ATGGAGACTT TGTACCGTGT CCCGTTCTTA GTGCTCGAAT GTCCCAACCT GAAGCTGAAG 
AAGCCGCCCT GGTTGCACAT GCCGTCGGCC ATGACTGTGT ATGCTCTGGT GGTGGTGTCT 
TACTTCCTCA TCACCGGAGG AATAATTTAT GATGTTATTG TTGAACCTCC AAGTGTCGGT 
TCTATGACTG ATGAACATGG GCATCAGAGG CCAGTAGCTT TCTTGGCCTA CAGAGTAAAT 
GGACAATATA TTATGGAAGG ACTTGCATCC AGCTTCCTAT TTACAATGGG AGGTTTAGGT 
TTCATAATCC TGGACCGATC GAATGCACCA AATATCCCAA AACTCAATAG ATTCCTTCTT 
CTGTTCATTG GATTCGTCTG TGTCCTATTG AGTTTTTTCA TGGCTAGAGT ATTCATGAGA 
ATGAAACTGC CGGGCTATCT GATGGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

OSTC ( NM_001267817.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254746.1 Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu00880
Clone ID Related Accession (Same CDS sequence)	NM_001267817.1
Accession Version	NM_001267817.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-14
Organism	Homo sapiens(human)
Product	oligosaccharyltransferase complex subunit OSTC isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC107071.3, CB110420.1, AF343342.1 and BM994257.1. Transcript Variant: This variant (2) lacks an exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.144726.1, SRR1163655.514061.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACTT TGTACCGTGT CCCGTTCTTA GTGCTCGAAT GTCCCAACCT GAAGCTGAAG 
AAGCCGCCCT GGTTGCACAT GCCGTCGGCC ATGACTGTGT ATGCTCTGGT GGTGGTGTCT 
TACTTCCTCA TCACCGGAGG AATAATTTAT GATGTTATTG TTGAACCTCC AAGTGTCGGT 
TCTATGACTG ATGAACATGG GCATCAGAGG CCAGTAGCTT TCTTGGCCTA CAGGGGCTAT 
CTGATGGGTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254746.1
CDS	72..323
Translation	METLYRVPFLVLECPNLKLKKPPWLHMPSAMTVYALVVVSYFLITGGIIYDVIVEPPSVGSMTDEHGHQRPVAFLAYRGYLMG

Target ORF information:

RefSeq Version	NM_001267817.1
Organism	Homo sapiens(human)
Definition	Homo sapiens oligosaccharyltransferase complex non-catalytic subunit (OSTC), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267817.1

ORF Insert Sequence:

ATGGAGACTT TGTACCGTGT CCCGTTCTTA GTGCTCGAAT GTCCCAACCT GAAGCTGAAG 
AAGCCGCCCT GGTTGCACAT GCCGTCGGCC ATGACTGTGT ATGCTCTGGT GGTGGTGTCT 
TACTTCCTCA TCACCGGAGG AATAATTTAT GATGTTATTG TTGAACCTCC AAGTGTCGGT 
TCTATGACTG ATGAACATGG GCATCAGAGG CCAGTAGCTT TCTTGGCCTA CAGGGGCTAT 
CTGATGGGTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.
The Journal of cell biology216(11)3625-3638(2017 Nov)
Shrimal S,Cherepanova NA,Gilmore R

Heat shock induces expression of OSTC/DC2, a?novel subunit of oligosaccharyltransferase, in?vitro and in?vivo.
The Kaohsiung journal of medical sciences30(5)219-23(2014 May)
Chen CM,Tseng CN,Cho JJ,Lee YZ,Kao CL,Cheng YB,Hong YR,Cho CL

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Human molecular genetics19(12)2497-506(2010 Jun)
Kalsi G,Kuo PH,Aliev F,Alexander J,McMichael O,Patterson DG,Walsh D,Zhao Z,Schuckit M,Nurnberger J Jr,Edenberg H,Kramer J,Hesselbrock V,Tischfield JA,Vladimirov V,Prescott CA,Dick DM,Kendler KS,Riley BP

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.
Biochemical and biophysical research communications345(3)1022-32(2006 Jul)
Wang AG,Yoon SY,Oh JH,Jeon YJ,Kim M,Kim JM,Byun SS,Yang JO,Kim JH,Kim DG,Yeom YI,Yoo HS,Kim YS,Kim NS

Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits.
Biochemistry44(16)5982-92(2005 Apr)
Shibatani T,David LL,McCormack AL,Frueh K,Skach WR

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OSTC cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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