Gene Symbol | PSMG1 |
Entrez Gene ID | 8624 |
Full Name | proteasome assembly chaperone 1 |
Synonyms | C21LRP,DSCR2,LRPC21,PAC-1,PAC1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » PSMG1 cDNA ORF clone
Gene Symbol | PSMG1 |
Entrez Gene ID | 8624 |
Full Name | proteasome assembly chaperone 1 |
Synonyms | C21LRP,DSCR2,LRPC21,PAC-1,PAC1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_003720.3 | NP_003711.1 | proteasome assembly chaperone 1 isoform a |
NM_203433.2 | NP_982257.1 | proteasome assembly chaperone 1 isoform b |
XM_017028488.1 | XP_016883977.1 | proteasome assembly chaperone 1 isoform X1 |
NM_001320795.1 | NP_001307724.1 | proteasome assembly chaperone 1 isoform d |
XM_024452135.1 | XP_024307903.1 | proteasome assembly chaperone 1 isoform X1 |
NM_001261824.1 | NP_001248753.1 | proteasome assembly chaperone 1 isoform 3 |
NM_003720.4 | NP_003711.1 | proteasome assembly chaperone 1 isoform a |
LOC715758 | XP_001109110.1 | |
Bos taurus (cattle) | PSMG1 | NP_001069815.1 |
Gallus gallus (chicken) | PSMG1 | NP_001012561.1 |
Danio rerio (zebrafish) | psmg1 | NP_001002714.1 |
Canis lupus familiaris (dog) | LOC608101 | XP_849775.2 |
Homo sapiens (human) | PSMG1 | NP_003711.1 |
Pan troglodytes (chimpanzee) | PSMG1 | XP_531460.1 |
Rattus norvegicus (Norway rat) | Psmg1 | NP_001099361.1 |
Xenopus tropicalis (tropical clawed frog) | psmg1 | NP_001096329.1 |
Mus musculus (house mouse) | Psmg1 | NP_062410.1 |
Trisomy 21 Alters DNA Methylation in Parent-of-Origin-Dependent and -Independent Manners.
Alves da Silva AF, Machado FB, Pavarino ?C, Biselli-P?rico JM, Zampieri BL, da Silva Francisco Junior R, Mozer Rodrigues PT, Terra Machado D, Santos-Rebou?as CB, Gomes Fernandes M, Chuva de Sousa Lopes SM, Lopes Rios ?F, Medina-Acosta E
PloS one11(4)e0154108(2016)
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Rudnicka AR, Trompet S, M?larstig A, Baumert J, Bis JC, Guo X, Hottenga JJ, Shin SY, Lopez LM, Lahti J, Tanaka T, Yanek LR, Oudot-Mellakh T, Wilson JF, Navarro P, Huffman JE, Zemunik T, Redline S, Mehra R, Pulanic D, Rudan I, Wright AF, Kolcic I, Polasek O, Wild SH, Campbell H, Curb JD, Wallace R, Liu S, Eaton CB, Becker DM, Becker LC, Bandinelli S, R?ikk?nen K, Widen E, Palotie A, Fornage M, Green D, Gross M, Davies G, Harris SE, Liewald DC, Starr JM, Williams FM, Grant PJ, Spector TD, Strawbridge RJ, Silveira A, Sennblad B, Rivadeneira F, Uitterlinden AG, Franco OH, Hofman A, van Dongen J, Willemsen G, Boomsma DI, Yao J, Swords Jenny N, Haritunians T, McKnight B, Lumley T, Taylor KD, Rotter JI, Psaty BM, Peters A, Gieger C, Illig T, Grotevendt A, Homuth G, V?lzke H, Kocher T, Goel A, Franzosi MG, Seedorf U, Clarke R, Steri M, Tarasov KV, Sanna S, Schlessinger D, Stott DJ, Sattar N, Buckley BM, Rumley A, Lowe GD, McArdle WL, Chen MH, Tofler GH, Song J, Boerwinkle E, Folsom AR, Rose LM, Franco-Cereceda A, Teichert M, Ikram MA, Mosley TH, Bevan S, Dichgans M, Rothwell PM, Sudlow CL, Hopewell JC, Chambers JC, Saleheen D, Kooner JS, Danesh J, Nelson CP, Erdmann J, Reilly MP, Kathiresan S, Schunkert H, Morange PE, Ferrucci L, Eriksson JG, Jacobs D, Deary IJ, Soranzo N, Witteman JC, de Geus EJ, Tracy RP, Hayward C, Koenig W, Cucca F, Jukema JW, Eriksson P, Seshadri S, Markus HS, Watkins H, Samani NJ, , , , , , Wallaschofski H, Smith NL, Tregouet D, Ridker PM, Tang W, Strachan DP, Hamsten A, O'Donnell CJ
Circulation128(12)1310-24(2013 Sep)
Pseudomonas infection in children with early-onset Crohn's disease: an association with a mutation close to PSMG1.
Wagner J, Catto-Smith AG, Cameron DJ, Kirkwood CD
Inflammatory bowel diseases19(4)E58-9(2013 Mar-Apr)
Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)
Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma.
Igci YZ, Arslan A, Akarsu E, Erkilic S, Igci M, Oztuzcu S, Cengiz B, Gogebakan B, Cakmak EA, Demiryurek AT
Endocrine pathology22(2)86-96(2011 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
RNA-seq evidence of biallelic expression of PSMG1 and 10 neighboring genes in at least one primary human tissue tested indicates that the expression of PSMG1 is uncoupled from the control of the maternally inherited 5mCpG imprints at the WRB differentially methylated region (DMR) in disomic controls or trisomy (Down syndrome) individuals.
Title: Trisomy 21 Alters DNA Methylation in Parent-of-Origin-Dependent and -Independent Manners.
PSMG1 mutation is associated with Crohn's disease.
Title: Pseudomonas infection in children with early-onset Crohn's disease: an association with a mutation close to PSMG1.
PSMG1 gene expression is increased in classic variant of papillary thyroid carcinoma.
Title: Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma.
Data show that an additive gene-gene interaction involving TLR4, PSMG1, TNFRSF6B and IRGM was identified with CD.
Title: Interaction of Crohn's disease susceptibility genes in an Australian paediatric cohort.
DSCR2 was found to interact with PPARbeta and to inhibit it.
Title: Down syndrome critical region 2 protein inhibits the transcriptional activity of peroxisome proliferator-activated receptor beta in HEK293 cells.
The following PSMG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PSMG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu62073 | |
Clone ID Related Accession (Same CDS sequence) | NM_001320795.1 , XM_024452135.1 | |
Accession Version | NM_001320795.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-04 | |
Organism | Homo sapiens(human) | |
Product | proteasome assembly chaperone 1 isoform d | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BE779375.1, BU543452.1 and BQ008489.1. On Mar 5, 2016 this sequence version replaced XM_011529771.1. Transcript Variant: This variant (5) uses an alternate splice site in the 5' coding region, which results in use of a downstream start AUG compared to variant 1. It encodes isoform d, which has a shorter N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.140106.1, SRR1803614.20989.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGAATTCAG GAGTCTGGGA GGAAGTTGGT TGTGCTAAAC TCTGGAATGA ATGGTGTAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001307724.1 |
CDS | 579..1184 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001320795.1 |
1 | ATGAATTCAG GAGTCTGGGA GGAAGTTGGT TGTGCTAAAC TCTGGAATGA ATGGTGTAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu62073 | |
Clone ID Related Accession (Same CDS sequence) | NM_001320795.1 , XM_024452135.1 | |
Accession Version | XM_024452135.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | proteasome assembly chaperone 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATTCAG GAGTCTGGGA GGAAGTTGGT TGTGCTAAAC TCTGGAATGA ATGGTGTAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024307903.1 |
CDS | 292..897 |
Translation |
Target ORF information:
Target ORF information:
|
XM_024452135.1 |
1 | ATGAATTCAG GAGTCTGGGA GGAAGTTGGT TGTGCTAAAC TCTGGAATGA ATGGTGTAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu09982 | |
Clone ID Related Accession (Same CDS sequence) | NM_001261824.1 | |
Accession Version | NM_001261824.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Homo sapiens(human) | |
Product | proteasome assembly chaperone 1 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BE779375.1, BM462074.1, AA731200.1 and AW594615.1. Transcript Variant: This variant (3) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.238314.1, SRR1163655.252396.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGGCCA CGTTCTTCGG AGAGGTGGTG AAGGCGCCGT GCCGAGCTGG GACTGAGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001248753.1 |
CDS | 130..981 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001261824.1 |
1 | ATGGCGGCCA CGTTCTTCGG AGAGGTGGTG AAGGCGCCGT GCCGAGCTGG GACTGAGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu10081 | |
Clone ID Related Accession (Same CDS sequence) | NM_003720.3 , NM_003720.4 | |
Accession Version | NM_003720.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-22 | |
Organism | Homo sapiens(human) | |
Product | proteasome assembly chaperone 1 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BE779375.1, BR000236.1, AA731200.1 and AW594615.1. On May 17, 2012 this sequence version replaced NM_003720.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.149802.1, SRR1660809.121236.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGGCCA CGTTCTTCGG AGAGGTGGTG AAGGCGCCGT GCCGAGCTGG GACTGAGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_003711.1 |
CDS | 130..996 |
Translation |
Target ORF information:
Target ORF information:
|
NM_003720.3 |
1 | ATGGCGGCCA CGTTCTTCGG AGAGGTGGTG AAGGCGCCGT GCCGAGCTGG GACTGAGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu10081 | |
Clone ID Related Accession (Same CDS sequence) | NM_003720.3 , NM_003720.4 | |
Accession Version | NM_003720.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-24 | |
Organism | Homo sapiens(human) | |
Product | proteasome assembly chaperone 1 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BE779375.1, BR000236.1, AA731200.1, AW594615.1 and AF129408.4. On May 17, 2019 this sequence version replaced NM_003720.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.121236.1, SRR1803613.74855.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000331573.8/ ENSP00000329915.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGGCCA CGTTCTTCGG AGAGGTGGTG AAGGCGCCGT GCCGAGCTGG GACTGAGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_003711.1 |
CDS | 67..933 |
Translation |
Target ORF information:
Target ORF information:
|
NM_003720.4 |
1 | ATGGCGGCCA CGTTCTTCGG AGAGGTGGTG AAGGCGCCGT GCCGAGCTGG GACTGAGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu10096 | |
Clone ID Related Accession (Same CDS sequence) | NM_203433.2 | |
Accession Version | NM_203433.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 804bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-05 | |
Organism | Homo sapiens(human) | |
Product | proteasome assembly chaperone 1 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BE779375.1, AB451468.1, AA731200.1 and AW594615.1. On May 17, 2012 this sequence version replaced NM_203433.1. Transcript Variant: This variant (2) lacks an exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.211441.1, SRR1163655.237708.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGGCCA CGTTCTTCGG AGAGGTGGTG AAGGCGCCGT GCCGAGCTGG GACTGAGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_982257.1 |
CDS | 130..933 |
Translation |
Target ORF information:
Target ORF information:
|
NM_203433.2 |
1 | ATGGCGGCCA CGTTCTTCGG AGAGGTGGTG AAGGCGCCGT GCCGAGCTGG GACTGAGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu93321 | |
Clone ID Related Accession (Same CDS sequence) | XM_017028488.1 | |
Accession Version | XM_017028488.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | proteasome assembly chaperone 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATTCAG GAGTCTGGGA GGAAGTTGGT TGTGCTAAAC TCTGGAATGA ATGGTGTAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016883977.1 |
CDS | 305..847 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017028488.1 |
1 | ATGAATTCAG GAGTCTGGGA GGAAGTTGGT TGTGCTAAAC TCTGGAATGA ATGGTGTAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Trisomy 21 Alters DNA Methylation in Parent-of-Origin-Dependent and -Independent Manners. |
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. |
Pseudomonas infection in children with early-onset Crohn's disease: an association with a mutation close to PSMG1. |
Proteomic characterization of the human sperm nucleus. |
Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma. |