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NAT1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol NAT1
Entrez Gene ID 9
Full Name N-acetyltransferase 1 (arylamine N-acetyltransferase)
Synonyms AAC1, MNAT, NAT-1, NATI
General protein information
Preferred Names
arylamine N-acetyltransferase 1
Names
arylamine N-acetyltransferase 1
arylamide acetylase 1
N-acetyltransferase type 1
monomorphic arylamine N-acetyltransferase
NP_000653.3
NP_001153642.1
NP_001153643.1
NP_001153644.1
NP_001153645.1
NP_001153646.1
NP_001153647.1
NP_001153648.1
NP_001153651.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8p22

Summary This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]. lac of sum
Disorder MIM:

108345


mRNA and Protein(s)

mRNA Protein Name
NM_001160174 NP_001153646 arylamine N-acetyltransferase 1 isoform a
XM_011544687 XP_011542989 arylamine N-acetyltransferase 1 isoform X2
XM_011544688 XP_011542990 arylamine N-acetyltransferase 1 isoform X2
XM_006716410 XP_006716473 arylamine N-acetyltransferase 1 isoform X1
XM_011544689 XP_011542991 arylamine N-acetyltransferase 1 isoform X1
NM_001160179 NP_001153651 arylamine N-acetyltransferase 1 isoform a
NM_001160170 NP_001153642 arylamine N-acetyltransferase 1 isoform a
NM_001160171 NP_001153643 arylamine N-acetyltransferase 1 isoform a
NM_001160172 NP_001153644 arylamine N-acetyltransferase 1 isoform a
NM_001160173 NP_001153645 arylamine N-acetyltransferase 1 isoform a
NM_000662 NP_000653 arylamine N-acetyltransferase 1 isoform a
NM_001160175 NP_001153647 arylamine N-acetyltransferase 1 isoform b
NM_001160176 NP_001153648 arylamine N-acetyltransferase 1 isoform b
NM_001291962 NP_001278891 arylamine N-acetyltransferase 1 isoform b



Homo sapiens (human) NAT1 NP_001153648.1
Pan troglodytes (chimpanzee) NAT1 XP_519630.2
Macaca mulatta (Rhesus monkey) NAT1 XP_002805323.1
Bos taurus (cattle) NAT1 NP_001069040.1
Mus musculus (house mouse) Nat2 NP_001162049.1
Rattus norvegicus (Norway rat) Nat2 NP_446306.1
Gallus gallus (chicken) PNAT3 NP_001004373.1
Gallus gallus (chicken) PNAT10 NP_990671.1
Gallus gallus (chicken) NAT NP_990857.1
Danio rerio (zebrafish) zgc:101040 NP_001003588.1
Danio rerio (zebrafish) zgc:103601 NP_001005974.1
Danio rerio (zebrafish) si:dkey-78a14.5 XP_005169078.1
Danio rerio (zebrafish) LOC794381 XP_005169079.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following NAT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NAT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu24502
NM_001160174 Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu24566 XM_011544687 PREDICTED: Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $202.30
$289.00
OHu24566 XM_011544688 PREDICTED: Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $202.30
$289.00
OHu24502
XM_006716410 PREDICTED: Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu24502
XM_011544689 PREDICTED: Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu24502
NM_001160179 Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 9, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu24502
NM_001160170 Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu24502
NM_001160171 Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu24502
NM_001160172 Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu24502
NM_001160173 Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu24502
NM_000662 Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu24566 NM_001160175 Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 7, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $202.30
$289.00
OHu24566 NM_001160176 Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 8, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $202.30
$289.00
OHu24566 NM_001291962 Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 10, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $202.30
$289.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu24502
Clone ID Related Accession (Same CDS sequence) NM_000662 , NM_001160170 , NM_001160171 , NM_001160172 , NM_001160173 , NM_001160174 , NM_001160179 , XM_006716410 , XM_011544689
Accession Version NM_001160174.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 873bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 14-MAY-2014
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ581141.1, AC124242.6, BX647521.1, BU753390.1 and KC877218.1. On Jan 17, 2014 this sequence version replaced gi:237649127. Transcript Variant: This variant (6, also known as Type IIIA) represents use of an alternate promoter and differs in the 5' UTR, compared to variant 1. This variant is transcribed from a promoter immediately upstream of the coding exon known as P4 or promoter 1. Variants 1-6 and 9 all encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001153646.1
CDS381..1253
Misc Feature(1)372..374(+)
Misc Feature(2)381..383(+)
Misc Feature(3)438..1220(+)
Misc Feature(4)696..701(+)
Exon (1)1..2022
Gene:NAT1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001160174
Organism Homo sapiens (human)
Definition Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001160174

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24566
Clone ID Related Accession (Same CDS sequence) NM_001160175 , NM_001160176 , NM_001291962 , XM_011544687 , XM_011544688
Accession Version XM_011544687.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1059bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167187.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCTGTTAT TACTCTTACA CAAGGAGGCA GCCCTCGAGC CACAGGGTCC AGCTGTTGGC 
TATAATAGCC TACCGGTCTC TGATGATCAC CATGTTTCTG GAATTCAAGC CAGGAAGAAG
CAGCAATCTG TCTTCTGGAT TAAAACTGAA GATCAACCTA CTTTCAACTT ACTAAGAAAG
GGGATCATGG ACATTGAAGC ATATCTTGAA AGAATTGGCT ATAAGAAGTC TAGGAACAAA
TTGGACTTGG AAACATTAAC TGACATTCTT CAACACCAGA TCCGAGCTGT TCCCTTTGAG
AACCTTAACA TCCATTGTGG GGATGCCATG GACTTAGGCT TAGAGGCCAT TTTTGATCAA
GTTGTGAGAA GAAATCGGGG TGGATGGTGT CTCCAGGTCA ATCATCTTCT GTACTGGGCT
CTGACCACTA TTGGTTTTGA GACCACGATG TTGGGAGGGT ATGTTTACAG CACTCCAGCC
AAAAAATACA GCACTGGCAT GATTCACCTT CTCCTGCAGG TGACCATTGA TGGCAGGAAC
TACATTGTCG ATGCTGGGTT TGGACGCTCA TACCAGATGT GGCAGCCTCT GGAGTTAATT
TCTGGGAAGG ATCAGCCTCA GGTGCCTTGT GTCTTCCGTT TGACGGAAGA GAATGGATTC
TGGTATCTAG ACCAAATCAG AAGGGAACAG TACATTCCAA ATGAAGAATT TCTTCATTCT
GATCTCCTAG AAGACAGCAA ATACCGAAAA ATCTACTCCT TTACTCTTAA GCCTCGAACA
ATTGAAGATT TTGAGTCTAT GAATACATAC CTGCAGACAT CTCCATCATC TGTGTTTACT
AGTAAATCAT TTTGTTCCTT GCAGACCCCA GATGGGGTTC ACTGTTTGGT GGGCTTCACC
CTCACCCATA GGAGATTCAA TTATAAGGAC AATACAGATC TAATAGAGTT CAAGACTCTG
AGTGAGGAAG AAATAGAAAA AGTGCTGAAA AATATATTTA ATATTTCCTT GCAGAGAAAG
CTTGTGCCCA AACATGGTGA TAGATTTTTT ACTATTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011542989.1
CDS641..1699
Misc Feature(1)884..1666(+)
Translation

Target ORF information:

RefSeq Version XM_011544687
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011544687

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCTGTTAT TACTCTTACA CAAGGAGGCA GCCCTCGAGC CACAGGGTCC AGCTGTTGGC 
TATAATAGCC TACCGGTCTC TGATGATCAC CATGTTTCTG GAATTCAAGC CAGGAAGAAG
CAGCAATCTG TCTTCTGGAT TAAAACTGAA GATCAACCTA CTTTCAACTT ACTAAGAAAG
GGGATCATGG ACATTGAAGC ATATCTTGAA AGAATTGGCT ATAAGAAGTC TAGGAACAAA
TTGGACTTGG AAACATTAAC TGACATTCTT CAACACCAGA TCCGAGCTGT TCCCTTTGAG
AACCTTAACA TCCATTGTGG GGATGCCATG GACTTAGGCT TAGAGGCCAT TTTTGATCAA
GTTGTGAGAA GAAATCGGGG TGGATGGTGT CTCCAGGTCA ATCATCTTCT GTACTGGGCT
CTGACCACTA TTGGTTTTGA GACCACGATG TTGGGAGGGT ATGTTTACAG CACTCCAGCC
AAAAAATACA GCACTGGCAT GATTCACCTT CTCCTGCAGG TGACCATTGA TGGCAGGAAC
TACATTGTCG ATGCTGGGTT TGGACGCTCA TACCAGATGT GGCAGCCTCT GGAGTTAATT
TCTGGGAAGG ATCAGCCTCA GGTGCCTTGT GTCTTCCGTT TGACGGAAGA GAATGGATTC
TGGTATCTAG ACCAAATCAG AAGGGAACAG TACATTCCAA ATGAAGAATT TCTTCATTCT
GATCTCCTAG AAGACAGCAA ATACCGAAAA ATCTACTCCT TTACTCTTAA GCCTCGAACA
ATTGAAGATT TTGAGTCTAT GAATACATAC CTGCAGACAT CTCCATCATC TGTGTTTACT
AGTAAATCAT TTTGTTCCTT GCAGACCCCA GATGGGGTTC ACTGTTTGGT GGGCTTCACC
CTCACCCATA GGAGATTCAA TTATAAGGAC AATACAGATC TAATAGAGTT CAAGACTCTG
AGTGAGGAAG AAATAGAAAA AGTGCTGAAA AATATATTTA ATATTTCCTT GCAGAGAAAG
CTTGTGCCCA AACATGGTGA TAGATTTTTT ACTATTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24566
Clone ID Related Accession (Same CDS sequence) NM_001160175 , NM_001160176 , NM_001291962 , XM_011544687 , XM_011544688
Accession Version XM_011544688.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1059bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167187.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCTGTTAT TACTCTTACA CAAGGAGGCA GCCCTCGAGC CACAGGGTCC AGCTGTTGGC 
TATAATAGCC TACCGGTCTC TGATGATCAC CATGTTTCTG GAATTCAAGC CAGGAAGAAG
CAGCAATCTG TCTTCTGGAT TAAAACTGAA GATCAACCTA CTTTCAACTT ACTAAGAAAG
GGGATCATGG ACATTGAAGC ATATCTTGAA AGAATTGGCT ATAAGAAGTC TAGGAACAAA
TTGGACTTGG AAACATTAAC TGACATTCTT CAACACCAGA TCCGAGCTGT TCCCTTTGAG
AACCTTAACA TCCATTGTGG GGATGCCATG GACTTAGGCT TAGAGGCCAT TTTTGATCAA
GTTGTGAGAA GAAATCGGGG TGGATGGTGT CTCCAGGTCA ATCATCTTCT GTACTGGGCT
CTGACCACTA TTGGTTTTGA GACCACGATG TTGGGAGGGT ATGTTTACAG CACTCCAGCC
AAAAAATACA GCACTGGCAT GATTCACCTT CTCCTGCAGG TGACCATTGA TGGCAGGAAC
TACATTGTCG ATGCTGGGTT TGGACGCTCA TACCAGATGT GGCAGCCTCT GGAGTTAATT
TCTGGGAAGG ATCAGCCTCA GGTGCCTTGT GTCTTCCGTT TGACGGAAGA GAATGGATTC
TGGTATCTAG ACCAAATCAG AAGGGAACAG TACATTCCAA ATGAAGAATT TCTTCATTCT
GATCTCCTAG AAGACAGCAA ATACCGAAAA ATCTACTCCT TTACTCTTAA GCCTCGAACA
ATTGAAGATT TTGAGTCTAT GAATACATAC CTGCAGACAT CTCCATCATC TGTGTTTACT
AGTAAATCAT TTTGTTCCTT GCAGACCCCA GATGGGGTTC ACTGTTTGGT GGGCTTCACC
CTCACCCATA GGAGATTCAA TTATAAGGAC AATACAGATC TAATAGAGTT CAAGACTCTG
AGTGAGGAAG AAATAGAAAA AGTGCTGAAA AATATATTTA ATATTTCCTT GCAGAGAAAG
CTTGTGCCCA AACATGGTGA TAGATTTTTT ACTATTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011542990.1
CDS491..1549
Misc Feature(1)734..1516(+)
Translation

Target ORF information:

RefSeq Version XM_011544688
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011544688

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCTGTTAT TACTCTTACA CAAGGAGGCA GCCCTCGAGC CACAGGGTCC AGCTGTTGGC 
TATAATAGCC TACCGGTCTC TGATGATCAC CATGTTTCTG GAATTCAAGC CAGGAAGAAG
CAGCAATCTG TCTTCTGGAT TAAAACTGAA GATCAACCTA CTTTCAACTT ACTAAGAAAG
GGGATCATGG ACATTGAAGC ATATCTTGAA AGAATTGGCT ATAAGAAGTC TAGGAACAAA
TTGGACTTGG AAACATTAAC TGACATTCTT CAACACCAGA TCCGAGCTGT TCCCTTTGAG
AACCTTAACA TCCATTGTGG GGATGCCATG GACTTAGGCT TAGAGGCCAT TTTTGATCAA
GTTGTGAGAA GAAATCGGGG TGGATGGTGT CTCCAGGTCA ATCATCTTCT GTACTGGGCT
CTGACCACTA TTGGTTTTGA GACCACGATG TTGGGAGGGT ATGTTTACAG CACTCCAGCC
AAAAAATACA GCACTGGCAT GATTCACCTT CTCCTGCAGG TGACCATTGA TGGCAGGAAC
TACATTGTCG ATGCTGGGTT TGGACGCTCA TACCAGATGT GGCAGCCTCT GGAGTTAATT
TCTGGGAAGG ATCAGCCTCA GGTGCCTTGT GTCTTCCGTT TGACGGAAGA GAATGGATTC
TGGTATCTAG ACCAAATCAG AAGGGAACAG TACATTCCAA ATGAAGAATT TCTTCATTCT
GATCTCCTAG AAGACAGCAA ATACCGAAAA ATCTACTCCT TTACTCTTAA GCCTCGAACA
ATTGAAGATT TTGAGTCTAT GAATACATAC CTGCAGACAT CTCCATCATC TGTGTTTACT
AGTAAATCAT TTTGTTCCTT GCAGACCCCA GATGGGGTTC ACTGTTTGGT GGGCTTCACC
CTCACCCATA GGAGATTCAA TTATAAGGAC AATACAGATC TAATAGAGTT CAAGACTCTG
AGTGAGGAAG AAATAGAAAA AGTGCTGAAA AATATATTTA ATATTTCCTT GCAGAGAAAG
CTTGTGCCCA AACATGGTGA TAGATTTTTT ACTATTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24502
Clone ID Related Accession (Same CDS sequence) NM_000662 , NM_001160170 , NM_001160171 , NM_001160172 , NM_001160173 , NM_001160174 , NM_001160179 , XM_006716410 , XM_011544689
Accession Version XM_006716410.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 873bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167187.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578815522. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006716473.1
CDS716..1588
Misc Feature(1)773..1555(+)
Translation

Target ORF information:

RefSeq Version XM_006716410
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006716410

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24502
Clone ID Related Accession (Same CDS sequence) NM_000662 , NM_001160170 , NM_001160171 , NM_001160172 , NM_001160173 , NM_001160174 , NM_001160179 , XM_006716410 , XM_011544689
Accession Version XM_011544689.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 873bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167187.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011542991.1
CDS116..988
Misc Feature(1)173..955(+)
Translation

Target ORF information:

RefSeq Version XM_011544689
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011544689

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24502
Clone ID Related Accession (Same CDS sequence) NM_000662 , NM_001160170 , NM_001160171 , NM_001160172 , NM_001160173 , NM_001160174 , NM_001160179 , XM_006716410 , XM_011544689
Accession Version NM_001160179.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 873bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124242.6, CD702544.1, BX647521.1, BU753390.1 and KC877218.1. This sequence is a reference standard in the RefSeqGene project. On Jan 17, 2014 this sequence version replaced gi:237649008. Transcript Variant: This variant (9, also known as Type IA) has a distinct 5' UTR and represents use of an alternate promoter known as the NATa or P3 promoter, compared to variant 1. Variants 1-6 and 9 all encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on publications. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC013732.1, D90041.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001153651.1
CDS368..1240
Misc Feature(1)281..283(+)
Misc Feature(2)368..370(+)
Misc Feature(3)425..1207(+)
Misc Feature(4)683..688(+)
Exon (1)1..46
Gene:NAT1
Gene Synonym:
Exon (2)47..107
Gene:NAT1
Gene Synonym:
Exon (3)108..282
Gene:NAT1
Gene Synonym:
Exon (4)283..361
Gene:NAT1
Gene Synonym:
Exon (5)362..2009
Gene:NAT1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001160179
Organism Homo sapiens (human)
Definition Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 9, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001160179

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24502
Clone ID Related Accession (Same CDS sequence) NM_000662 , NM_001160170 , NM_001160171 , NM_001160172 , NM_001160173 , NM_001160174 , NM_001160179 , XM_006716410 , XM_011544689
Accession Version NM_001160170.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 873bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG655073.1, BG941635.1, AJ581138.1, BX647521.1 and BU753390.1. On May 14, 2014 this sequence version replaced gi:574957020. Transcript Variant: This variant (1) represents the longest transcript but encodes the shorter isoform (a). This variant is transcribed from a promoter known as P1, promoter 2, or NATb promoter. Variants 1-6 and 9 all encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC013732.1, D90041.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001153642.1
CDS698..1570
Misc Feature(1)581..583(+)
Misc Feature(2)698..700(+)
Misc Feature(3)755..1537(+)
Misc Feature(4)1013..1018(+)
Exon (1)1..78
Gene:NAT1
Gene Synonym:
Exon (2)79..228
Gene:NAT1
Gene Synonym:
Exon (3)229..612
Gene:NAT1
Gene Synonym:
Exon (4)613..691
Gene:NAT1
Gene Synonym:
Exon (5)692..2339
Gene:NAT1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001160170
Organism Homo sapiens (human)
Definition Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001160170

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24502
Clone ID Related Accession (Same CDS sequence) NM_000662 , NM_001160170 , NM_001160171 , NM_001160172 , NM_001160173 , NM_001160174 , NM_001160179 , XM_006716410 , XM_011544689
Accession Version NM_001160171.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 873bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG655073.1, BC013732.1, BX647521.1 and BU753390.1. On May 14, 2014 this sequence version replaced gi:574956996. Transcript Variant: This variant (2, also known as Type IID) lacks an alternate exon in the 5' UTR, compared to variant 1. This variant is transcribed from a promoter known as P1, promoter 2, or NATb promoter. Variants 1-6 and 9 all encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013732.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001153643.1
CDS548..1420
Misc Feature(1)431..433(+)
Misc Feature(2)548..550(+)
Misc Feature(3)605..1387(+)
Misc Feature(4)863..868(+)
Exon (1)1..78
Gene:NAT1
Gene Synonym:
Exon (2)79..462
Gene:NAT1
Gene Synonym:
Exon (3)463..541
Gene:NAT1
Gene Synonym:
Exon (4)542..2189
Gene:NAT1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001160171
Organism Homo sapiens (human)
Definition Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001160171

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24502
Clone ID Related Accession (Same CDS sequence) NM_000662 , NM_001160170 , NM_001160171 , NM_001160172 , NM_001160173 , NM_001160174 , NM_001160179 , XM_006716410 , XM_011544689
Accession Version NM_001160172.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 873bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG655073.1, BG941635.1, AJ581137.1, BX647521.1 and BU753390.1. On May 14, 2014 this sequence version replaced gi:574957170. Transcript Variant: This variant (3) uses an alternate splice site in the 5' UTR, compared to variant 1. This variant is transcribed from a promoter known as P1, promoter 2, or NATb promoter. Variants 1-6 and 9 all encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC013732.1, D90041.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001153644.1
CDS469..1341
Misc Feature(1)310..312(+)
Misc Feature(2)469..471(+)
Misc Feature(3)526..1308(+)
Misc Feature(4)784..789(+)
Exon (1)1..78
Gene:NAT1
Gene Synonym:
Exon (2)79..228
Gene:NAT1
Gene Synonym:
Exon (3)229..383
Gene:NAT1
Gene Synonym:
Exon (4)384..462
Gene:NAT1
Gene Synonym:
Exon (5)463..2110
Gene:NAT1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001160172
Organism Homo sapiens (human)
Definition Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001160172

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24502
Clone ID Related Accession (Same CDS sequence) NM_000662 , NM_001160170 , NM_001160171 , NM_001160172 , NM_001160173 , NM_001160174 , NM_001160179 , XM_006716410 , XM_011544689
Accession Version NM_001160173.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 873bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG655073.1, BG941635.1, AJ581136.1, BX647521.1 and BU753390.1. On May 14, 2014 this sequence version replaced gi:574957137. Transcript Variant: This variant (4, also known as Type IIC) lacks an alternate exon in the 5' UTR, compared to variant 1. This variant is transcribed from a promoter known as P1, promoter 2, or NATb promoter. Variants 1-6 and 9 all encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG941635.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2144835 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001153645.1
CDS314..1186
Misc Feature(1)227..229(+)
Misc Feature(2)314..316(+)
Misc Feature(3)371..1153(+)
Misc Feature(4)629..634(+)
Exon (1)1..78
Gene:NAT1
Gene Synonym:
Exon (2)79..228
Gene:NAT1
Gene Synonym:
Exon (3)229..307
Gene:NAT1
Gene Synonym:
Exon (4)308..1955
Gene:NAT1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001160173
Organism Homo sapiens (human)
Definition Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001160173

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24502
Clone ID Related Accession (Same CDS sequence) NM_000662 , NM_001160170 , NM_001160171 , NM_001160172 , NM_001160173 , NM_001160174 , NM_001160179 , XM_006716410 , XM_011544689
Accession Version NM_000662.7 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 873bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG655073.1, BC047666.1, BX647521.1 and BU753390.1. On May 14, 2014 this sequence version replaced gi:574956987. Transcript Variant: This variant (5, also known as Type IIA) lacks two alternate exons in the 5' UTR, compared to variant 1, and is the predominant transcript. This variant is transcribed from a promoter known as P1, promoter 2, or NATb promoter. Variants 1-6 and 9 all encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC047666.1, BQ231158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000653.3
CDS164..1036
Misc Feature(1)77..79(+)
Misc Feature(2)164..166(+)
Misc Feature(3)221..1003(+)
Misc Feature(4)365..367(+)
Misc Feature(5)479..484(+)
Exon (1)1..78
Gene:NAT1
Gene Synonym:
Exon (2)79..157
Gene:NAT1
Gene Synonym:
Exon (3)158..1805
Gene:NAT1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000662
Organism Homo sapiens (human)
Definition Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000662

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGACATTG AAGCATATCT TGAAAGAATT GGCTATAAGA AGTCTAGGAA CAAATTGGAC 
TTGGAAACAT TAACTGACAT TCTTCAACAC CAGATCCGAG CTGTTCCCTT TGAGAACCTT
AACATCCATT GTGGGGATGC CATGGACTTA GGCTTAGAGG CCATTTTTGA TCAAGTTGTG
AGAAGAAATC GGGGTGGATG GTGTCTCCAG GTCAATCATC TTCTGTACTG GGCTCTGACC
ACTATTGGTT TTGAGACCAC GATGTTGGGA GGGTATGTTT ACAGCACTCC AGCCAAAAAA
TACAGCACTG GCATGATTCA CCTTCTCCTG CAGGTGACCA TTGATGGCAG GAACTACATT
GTCGATGCTG GGTTTGGACG CTCATACCAG ATGTGGCAGC CTCTGGAGTT AATTTCTGGG
AAGGATCAGC CTCAGGTGCC TTGTGTCTTC CGTTTGACGG AAGAGAATGG ATTCTGGTAT
CTAGACCAAA TCAGAAGGGA ACAGTACATT CCAAATGAAG AATTTCTTCA TTCTGATCTC
CTAGAAGACA GCAAATACCG AAAAATCTAC TCCTTTACTC TTAAGCCTCG AACAATTGAA
GATTTTGAGT CTATGAATAC ATACCTGCAG ACATCTCCAT CATCTGTGTT TACTAGTAAA
TCATTTTGTT CCTTGCAGAC CCCAGATGGG GTTCACTGTT TGGTGGGCTT CACCCTCACC
CATAGGAGAT TCAATTATAA GGACAATACA GATCTAATAG AGTTCAAGAC TCTGAGTGAG
GAAGAAATAG AAAAAGTGCT GAAAAATATA TTTAATATTT CCTTGCAGAG AAAGCTTGTG
CCCAAACATG GTGATAGATT TTTTACTATT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24566
Clone ID Related Accession (Same CDS sequence) NM_001160175 , NM_001160176 , NM_001291962 , XM_011544687 , XM_011544688
Accession Version NM_001160175.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1059bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG655073.1, BG941635.1, AJ581139.1, BX647521.1 and BU753390.1. On May 14, 2014 this sequence version replaced gi:574957029. Transcript Variant: This variant (7) lacks an alternate 5' non-coding exon and includes an additional exon resulting in translation from an alternate start codon, compared to variant 1. The resulting isoform (b) has a longer N-terminus, compared to isoform a. Variants 7, 8 and 10 all encode isoform b. This variant is transcribed from a promoter known as P1, promoter 2, or NATb promoter. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BX647521.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCTGTTAT TACTCTTACA CAAGGAGGCA GCCCTCGAGC CACAGGGTCC AGCTGTTGGC 
TATAATAGCC TACCGGTCTC TGATGATCAC CATGTTTCTG GAATTCAAGC CAGGAAGAAG
CAGCAATCTG TCTTCTGGAT TAAAACTGAA GATCAACCTA CTTTCAACTT ACTAAGAAAG
GGGATCATGG ACATTGAAGC ATATCTTGAA AGAATTGGCT ATAAGAAGTC TAGGAACAAA
TTGGACTTGG AAACATTAAC TGACATTCTT CAACACCAGA TCCGAGCTGT TCCCTTTGAG
AACCTTAACA TCCATTGTGG GGATGCCATG GACTTAGGCT TAGAGGCCAT TTTTGATCAA
GTTGTGAGAA GAAATCGGGG TGGATGGTGT CTCCAGGTCA ATCATCTTCT GTACTGGGCT
CTGACCACTA TTGGTTTTGA GACCACGATG TTGGGAGGGT ATGTTTACAG CACTCCAGCC
AAAAAATACA GCACTGGCAT GATTCACCTT CTCCTGCAGG TGACCATTGA TGGCAGGAAC
TACATTGTCG ATGCTGGGTT TGGACGCTCA TACCAGATGT GGCAGCCTCT GGAGTTAATT
TCTGGGAAGG ATCAGCCTCA GGTGCCTTGT GTCTTCCGTT TGACGGAAGA GAATGGATTC
TGGTATCTAG ACCAAATCAG AAGGGAACAG TACATTCCAA ATGAAGAATT TCTTCATTCT
GATCTCCTAG AAGACAGCAA ATACCGAAAA ATCTACTCCT TTACTCTTAA GCCTCGAACA
ATTGAAGATT TTGAGTCTAT GAATACATAC CTGCAGACAT CTCCATCATC TGTGTTTACT
AGTAAATCAT TTTGTTCCTT GCAGACCCCA GATGGGGTTC ACTGTTTGGT GGGCTTCACC
CTCACCCATA GGAGATTCAA TTATAAGGAC AATACAGATC TAATAGAGTT CAAGACTCTG
AGTGAGGAAG AAATAGAAAA AGTGCTGAAA AATATATTTA ATATTTCCTT GCAGAGAAAG
CTTGTGCCCA AACATGGTGA TAGATTTTTT ACTATTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001153647.1
CDS246..1304
Misc Feature(1)207..209(+)
Misc Feature(2)489..1271(+)
Exon (1)1..78
Gene:NAT1
Gene Synonym:
Exon (2)79..228
Gene:NAT1
Gene Synonym:
Exon (3)229..346
Gene:NAT1
Gene Synonym:
Exon (4)347..425
Gene:NAT1
Gene Synonym:
Exon (5)426..2073
Gene:NAT1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001160175
Organism Homo sapiens (human)
Definition Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 7, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001160175

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCTGTTAT TACTCTTACA CAAGGAGGCA GCCCTCGAGC CACAGGGTCC AGCTGTTGGC 
TATAATAGCC TACCGGTCTC TGATGATCAC CATGTTTCTG GAATTCAAGC CAGGAAGAAG
CAGCAATCTG TCTTCTGGAT TAAAACTGAA GATCAACCTA CTTTCAACTT ACTAAGAAAG
GGGATCATGG ACATTGAAGC ATATCTTGAA AGAATTGGCT ATAAGAAGTC TAGGAACAAA
TTGGACTTGG AAACATTAAC TGACATTCTT CAACACCAGA TCCGAGCTGT TCCCTTTGAG
AACCTTAACA TCCATTGTGG GGATGCCATG GACTTAGGCT TAGAGGCCAT TTTTGATCAA
GTTGTGAGAA GAAATCGGGG TGGATGGTGT CTCCAGGTCA ATCATCTTCT GTACTGGGCT
CTGACCACTA TTGGTTTTGA GACCACGATG TTGGGAGGGT ATGTTTACAG CACTCCAGCC
AAAAAATACA GCACTGGCAT GATTCACCTT CTCCTGCAGG TGACCATTGA TGGCAGGAAC
TACATTGTCG ATGCTGGGTT TGGACGCTCA TACCAGATGT GGCAGCCTCT GGAGTTAATT
TCTGGGAAGG ATCAGCCTCA GGTGCCTTGT GTCTTCCGTT TGACGGAAGA GAATGGATTC
TGGTATCTAG ACCAAATCAG AAGGGAACAG TACATTCCAA ATGAAGAATT TCTTCATTCT
GATCTCCTAG AAGACAGCAA ATACCGAAAA ATCTACTCCT TTACTCTTAA GCCTCGAACA
ATTGAAGATT TTGAGTCTAT GAATACATAC CTGCAGACAT CTCCATCATC TGTGTTTACT
AGTAAATCAT TTTGTTCCTT GCAGACCCCA GATGGGGTTC ACTGTTTGGT GGGCTTCACC
CTCACCCATA GGAGATTCAA TTATAAGGAC AATACAGATC TAATAGAGTT CAAGACTCTG
AGTGAGGAAG AAATAGAAAA AGTGCTGAAA AATATATTTA ATATTTCCTT GCAGAGAAAG
CTTGTGCCCA AACATGGTGA TAGATTTTTT ACTATTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24566
Clone ID Related Accession (Same CDS sequence) NM_001160175 , NM_001160176 , NM_001291962 , XM_011544687 , XM_011544688
Accession Version NM_001160176.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1059bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG655073.1, BX647521.1, AC124242.6 and BU753390.1. On May 14, 2014 this sequence version replaced gi:574956990. Transcript Variant: This variant (8, also known as Type IIB) lacks two alternate 5' non-coding exons and includes an additional exon resulting in translation from an alternate start codon, compared to variant 1. The resulting isoform (b) has a longer N-terminus, compared to isoform a. Variants 7, 8 and 10 all encode isoform b. This variant is transcribed from a promoter known as P1, promoter 2, or NATb promoter. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX647521.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCTGTTAT TACTCTTACA CAAGGAGGCA GCCCTCGAGC CACAGGGTCC AGCTGTTGGC 
TATAATAGCC TACCGGTCTC TGATGATCAC CATGTTTCTG GAATTCAAGC CAGGAAGAAG
CAGCAATCTG TCTTCTGGAT TAAAACTGAA GATCAACCTA CTTTCAACTT ACTAAGAAAG
GGGATCATGG ACATTGAAGC ATATCTTGAA AGAATTGGCT ATAAGAAGTC TAGGAACAAA
TTGGACTTGG AAACATTAAC TGACATTCTT CAACACCAGA TCCGAGCTGT TCCCTTTGAG
AACCTTAACA TCCATTGTGG GGATGCCATG GACTTAGGCT TAGAGGCCAT TTTTGATCAA
GTTGTGAGAA GAAATCGGGG TGGATGGTGT CTCCAGGTCA ATCATCTTCT GTACTGGGCT
CTGACCACTA TTGGTTTTGA GACCACGATG TTGGGAGGGT ATGTTTACAG CACTCCAGCC
AAAAAATACA GCACTGGCAT GATTCACCTT CTCCTGCAGG TGACCATTGA TGGCAGGAAC
TACATTGTCG ATGCTGGGTT TGGACGCTCA TACCAGATGT GGCAGCCTCT GGAGTTAATT
TCTGGGAAGG ATCAGCCTCA GGTGCCTTGT GTCTTCCGTT TGACGGAAGA GAATGGATTC
TGGTATCTAG ACCAAATCAG AAGGGAACAG TACATTCCAA ATGAAGAATT TCTTCATTCT
GATCTCCTAG AAGACAGCAA ATACCGAAAA ATCTACTCCT TTACTCTTAA GCCTCGAACA
ATTGAAGATT TTGAGTCTAT GAATACATAC CTGCAGACAT CTCCATCATC TGTGTTTACT
AGTAAATCAT TTTGTTCCTT GCAGACCCCA GATGGGGTTC ACTGTTTGGT GGGCTTCACC
CTCACCCATA GGAGATTCAA TTATAAGGAC AATACAGATC TAATAGAGTT CAAGACTCTG
AGTGAGGAAG AAATAGAAAA AGTGCTGAAA AATATATTTA ATATTTCCTT GCAGAGAAAG
CTTGTGCCCA AACATGGTGA TAGATTTTTT ACTATTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001153648.1
CDS96..1154
Misc Feature(1)72..74(+)
Misc Feature(2)339..1121(+)
Exon (1)1..78
Gene:NAT1
Gene Synonym:
Exon (2)79..196
Gene:NAT1
Gene Synonym:
Exon (3)197..275
Gene:NAT1
Gene Synonym:
Exon (4)276..1923
Gene:NAT1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001160176
Organism Homo sapiens (human)
Definition Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 8, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001160176

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCTGTTAT TACTCTTACA CAAGGAGGCA GCCCTCGAGC CACAGGGTCC AGCTGTTGGC 
TATAATAGCC TACCGGTCTC TGATGATCAC CATGTTTCTG GAATTCAAGC CAGGAAGAAG
CAGCAATCTG TCTTCTGGAT TAAAACTGAA GATCAACCTA CTTTCAACTT ACTAAGAAAG
GGGATCATGG ACATTGAAGC ATATCTTGAA AGAATTGGCT ATAAGAAGTC TAGGAACAAA
TTGGACTTGG AAACATTAAC TGACATTCTT CAACACCAGA TCCGAGCTGT TCCCTTTGAG
AACCTTAACA TCCATTGTGG GGATGCCATG GACTTAGGCT TAGAGGCCAT TTTTGATCAA
GTTGTGAGAA GAAATCGGGG TGGATGGTGT CTCCAGGTCA ATCATCTTCT GTACTGGGCT
CTGACCACTA TTGGTTTTGA GACCACGATG TTGGGAGGGT ATGTTTACAG CACTCCAGCC
AAAAAATACA GCACTGGCAT GATTCACCTT CTCCTGCAGG TGACCATTGA TGGCAGGAAC
TACATTGTCG ATGCTGGGTT TGGACGCTCA TACCAGATGT GGCAGCCTCT GGAGTTAATT
TCTGGGAAGG ATCAGCCTCA GGTGCCTTGT GTCTTCCGTT TGACGGAAGA GAATGGATTC
TGGTATCTAG ACCAAATCAG AAGGGAACAG TACATTCCAA ATGAAGAATT TCTTCATTCT
GATCTCCTAG AAGACAGCAA ATACCGAAAA ATCTACTCCT TTACTCTTAA GCCTCGAACA
ATTGAAGATT TTGAGTCTAT GAATACATAC CTGCAGACAT CTCCATCATC TGTGTTTACT
AGTAAATCAT TTTGTTCCTT GCAGACCCCA GATGGGGTTC ACTGTTTGGT GGGCTTCACC
CTCACCCATA GGAGATTCAA TTATAAGGAC AATACAGATC TAATAGAGTT CAAGACTCTG
AGTGAGGAAG AAATAGAAAA AGTGCTGAAA AATATATTTA ATATTTCCTT GCAGAGAAAG
CTTGTGCCCA AACATGGTGA TAGATTTTTT ACTATTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24566
Clone ID Related Accession (Same CDS sequence) NM_001160175 , NM_001160176 , NM_001291962 , XM_011544687 , XM_011544688
Accession Version NM_001291962.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1059bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 13-MAY-2015
Organism Homo sapiens (human)
Product arylamine N-acetyltransferase 1 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124242.6, BM924372.1, BX647521.1 and BU753390.1. Transcript Variant: This variant (10, also known as Type IB) contains alternate 5' exon structure and it thus differs in the 5' UTR and initiates translation from an alternate start codon, compared to variant 1. The resulting isoform (b) has a longer N-terminus, compared to isoform a. This variant is transcribed from a promoter known as P1, promoter 2, or NATb promoter. Variants 7, 8 and 10 all encode isoform b. This variant is transcribed from an alternate promoter known as the NATa or P3 promoter. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BX647521.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCTGTTAT TACTCTTACA CAAGGAGGCA GCCCTCGAGC CACAGGGTCC AGCTGTTGGC 
TATAATAGCC TACCGGTCTC TGATGATCAC CATGTTTCTG GAATTCAAGC CAGGAAGAAG
CAGCAATCTG TCTTCTGGAT TAAAACTGAA GATCAACCTA CTTTCAACTT ACTAAGAAAG
GGGATCATGG ACATTGAAGC ATATCTTGAA AGAATTGGCT ATAAGAAGTC TAGGAACAAA
TTGGACTTGG AAACATTAAC TGACATTCTT CAACACCAGA TCCGAGCTGT TCCCTTTGAG
AACCTTAACA TCCATTGTGG GGATGCCATG GACTTAGGCT TAGAGGCCAT TTTTGATCAA
GTTGTGAGAA GAAATCGGGG TGGATGGTGT CTCCAGGTCA ATCATCTTCT GTACTGGGCT
CTGACCACTA TTGGTTTTGA GACCACGATG TTGGGAGGGT ATGTTTACAG CACTCCAGCC
AAAAAATACA GCACTGGCAT GATTCACCTT CTCCTGCAGG TGACCATTGA TGGCAGGAAC
TACATTGTCG ATGCTGGGTT TGGACGCTCA TACCAGATGT GGCAGCCTCT GGAGTTAATT
TCTGGGAAGG ATCAGCCTCA GGTGCCTTGT GTCTTCCGTT TGACGGAAGA GAATGGATTC
TGGTATCTAG ACCAAATCAG AAGGGAACAG TACATTCCAA ATGAAGAATT TCTTCATTCT
GATCTCCTAG AAGACAGCAA ATACCGAAAA ATCTACTCCT TTACTCTTAA GCCTCGAACA
ATTGAAGATT TTGAGTCTAT GAATACATAC CTGCAGACAT CTCCATCATC TGTGTTTACT
AGTAAATCAT TTTGTTCCTT GCAGACCCCA GATGGGGTTC ACTGTTTGGT GGGCTTCACC
CTCACCCATA GGAGATTCAA TTATAAGGAC AATACAGATC TAATAGAGTT CAAGACTCTG
AGTGAGGAAG AAATAGAAAA AGTGCTGAAA AATATATTTA ATATTTCCTT GCAGAGAAAG
CTTGTGCCCA AACATGGTGA TAGATTTTTT ACTATTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278891.1
CDS300..1358
Misc Feature(1)213..215(+)
Misc Feature(2)543..1325(+)
Exon (1)1..46
Gene:NAT1
Gene Synonym:
Exon (2)47..107
Gene:NAT1
Gene Synonym:
Exon (3)108..282
Gene:NAT1
Gene Synonym:
Exon (4)283..400
Gene:NAT1
Gene Synonym:
Exon (5)401..479
Gene:NAT1
Gene Synonym:
Exon (6)480..2127
Gene:NAT1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001291962
Organism Homo sapiens (human)
Definition Homo sapiens N-acetyltransferase 1 (arylamine N-acetyltransferase) (NAT1), transcript variant 10, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001291962

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCTGTTAT TACTCTTACA CAAGGAGGCA GCCCTCGAGC CACAGGGTCC AGCTGTTGGC 
TATAATAGCC TACCGGTCTC TGATGATCAC CATGTTTCTG GAATTCAAGC CAGGAAGAAG
CAGCAATCTG TCTTCTGGAT TAAAACTGAA GATCAACCTA CTTTCAACTT ACTAAGAAAG
GGGATCATGG ACATTGAAGC ATATCTTGAA AGAATTGGCT ATAAGAAGTC TAGGAACAAA
TTGGACTTGG AAACATTAAC TGACATTCTT CAACACCAGA TCCGAGCTGT TCCCTTTGAG
AACCTTAACA TCCATTGTGG GGATGCCATG GACTTAGGCT TAGAGGCCAT TTTTGATCAA
GTTGTGAGAA GAAATCGGGG TGGATGGTGT CTCCAGGTCA ATCATCTTCT GTACTGGGCT
CTGACCACTA TTGGTTTTGA GACCACGATG TTGGGAGGGT ATGTTTACAG CACTCCAGCC
AAAAAATACA GCACTGGCAT GATTCACCTT CTCCTGCAGG TGACCATTGA TGGCAGGAAC
TACATTGTCG ATGCTGGGTT TGGACGCTCA TACCAGATGT GGCAGCCTCT GGAGTTAATT
TCTGGGAAGG ATCAGCCTCA GGTGCCTTGT GTCTTCCGTT TGACGGAAGA GAATGGATTC
TGGTATCTAG ACCAAATCAG AAGGGAACAG TACATTCCAA ATGAAGAATT TCTTCATTCT
GATCTCCTAG AAGACAGCAA ATACCGAAAA ATCTACTCCT TTACTCTTAA GCCTCGAACA
ATTGAAGATT TTGAGTCTAT GAATACATAC CTGCAGACAT CTCCATCATC TGTGTTTACT
AGTAAATCAT TTTGTTCCTT GCAGACCCCA GATGGGGTTC ACTGTTTGGT GGGCTTCACC
CTCACCCATA GGAGATTCAA TTATAAGGAC AATACAGATC TAATAGAGTT CAAGACTCTG
AGTGAGGAAG AAATAGAAAA AGTGCTGAAA AATATATTTA ATATTTCCTT GCAGAGAAAG
CTTGTGCCCA AACATGGTGA TAGATTTTTT ACTATTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Crippling the essential GTPase Der causes dependence on ribosomal protein L9
J. Bacteriol. 195 (16), 3682-3691 (2013)
Naganathan A and Moore SD.


book

Arylamine N-acetyltransferase I
Int. J. Biochem. Cell Biol. 39 (11), 1999-2005 (2007)
Minchin RF, Hanna PE, Dupret JM, Wagner CR, Rodrigues-Lima F and Butcher NJ.


book

Functional properties of an alternative, tissue-specific promoter for human arylamine N-acetyltransferase 1
Pharmacogenet. Genomics 16 (7), 515-525 (2006)
Barker DF, Husain A, Neale JR, Martini BD, Zhang X, Doll MA, States JC and Hein DW.


book

Structural analysis of the genes for human arylamine N-acetyltransferases and characterisation of alternative transcripts
Basic Clin. Pharmacol. Toxicol. 96 (5), 343-351 (2005)
Boukouvala S and Sim E.


book

Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5'-UTR splice variants with altered translational activities
Biochem. J. 387 (PT 1), 119-127 (2005)
Butcher NJ, Arulpragasam A, Goh HL, Davey T and Minchin RF.


book

Identification of the major promoter and non-coding exons of the human arylamine N-acetyltransferase 1 gene (NAT1)
Pharmacogenetics 14 (7), 397-406 (2004)
Husain A, Barker DF, States JC, Doll MA and Hein DW.


book

Identification of a minimal promoter sequence for the human N-acetyltransferase Type I gene that binds AP-1 (activator protein 1) and YY-1 (Yin and Yang 1)
Biochem. J. 376 (PT 2), 441-448 (2003)
Butcher NJ, Arulpragasam A, Pope C and Minchin RF.


book

Site-directed mutagenesis of recombinant human arylamine N-acetyltransferase expressed in Escherichia coli. Evidence for direct involvement of Cys68 in the catalytic mechanism of polymorphic human NAT2
J. Biol. Chem. 267 (11), 7381-7385 (1992)
Dupret JM and Grant DM.


book

Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression
DNA Cell Biol. 9 (3), 193-203 (1990)
Blum M, Grant DM, McBride W, Heim M and Meyer UA.


book

Cloning and expression of cDNAs for polymorphic and monomorphic arylamine N-acetyltransferases from human liver
J. Biol. Chem. 265 (8), 4630-4634 (1990)
Ohsako S and Deguchi T.


 
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