Gene Symbol | CIR1 |
Entrez Gene ID | 9541 |
Full Name | corepressor interacting with RBPJ, 1 |
Synonyms | CIR |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » CIR1 cDNA ORF clone
Gene Symbol | CIR1 |
Entrez Gene ID | 9541 |
Full Name | corepressor interacting with RBPJ, 1 |
Synonyms | CIR |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_004882.4 | NP_004873.3 | corepressor interacting with RBPJ 1 |
NM_004882.3 | NP_004873.3 | corepressor interacting with RBPJ 1 |
LOC698068 | XP_002808060.1 | |
Gallus gallus (chicken) | CIR1 | NP_001026557.1 |
Danio rerio (zebrafish) | si:ch73-167c12.2 | XP_689017.6 |
Homo sapiens (human) | CIR1 | NP_004873.3 |
Canis lupus familiaris (dog) | CIR1 | XP_535968.2 |
Mus musculus (house mouse) | Cir1 | NP_080130.2 |
Pan troglodytes (chimpanzee) | CIR1 | XP_001148591.1 |
Rattus norvegicus (Norway rat) | Cir1 | NP_001007800.1 |
Polymorphisms in cancer-related pathway genes and lung cancer.
Lee SY, Kang HG, Choi JE, Jung DK, Lee WK, Lee HC, Lee SY, Yoo SS, Lee J, Seok Y, Lee EB, Cha SI, Cho S, Kim CH, Lee MH, Park JY
The European respiratory journal48(4)1184-1191(2016 Oct)
Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome.
Vaz Meirelles G, Ferreira Lanza DC, da Silva JC, Santana Bernachi J, Paes Leme AF, Kobarg J
Journal of proteome research9(12)6298-316(2010 Dec)
NKAP is a transcriptional repressor of notch signaling and is required for T cell development.
Pajerowski AG, Nguyen C, Aghajanian H, Shapiro MJ, Shapiro VS
Immunity30(5)696-707(2009 May)
Slug is a direct Notch target required for initiation of cardiac cushion cellularization.
Niessen K, Fu Y, Chang L, Hoodless PA, McFadden D, Karsan A
The Journal of cell biology182(2)315-25(2008 Jul)
CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing.
Maita H, Kitaura H, Ariga H, Iguchi-Ariga SM
Experimental cell research303(2)375-87(2005 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
identified as a PAP-1 binding protein and as a splicing factor
Title: CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing.
The following CIR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CIR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu04668 | |
Clone ID Related Accession (Same CDS sequence) | NM_004882.4 , NM_004882.3 | |
Accession Version | NM_004882.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1353bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-30 | |
Organism | Homo sapiens(human) | |
Product | corepressor interacting with RBPJ 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU596189.1, BC046098.2, BC015040.1 and AC018470.11. On Nov 23, 2018 this sequence version replaced NM_004882.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.7939.1, SRR1803613.130520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000342016.8/ ENSP00000339723.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGGGAAAT CCTTCGCCAA CTTCATGTGC AAGAAAGACT TTCATCCTGC CTCCAAATCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_004873.3 |
CDS | 91..1443 |
Translation |
Target ORF information:
Target ORF information:
|
NM_004882.4 |
1 | ATGGGGAAAT CCTTCGCCAA CTTCATGTGC AAGAAAGACT TTCATCCTGC CTCCAAATCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu04668 | |
Clone ID Related Accession (Same CDS sequence) | NM_004882.4 , NM_004882.3 | |
Accession Version | NM_004882.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1353bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Homo sapiens(human) | |
Product | corepressor interacting with RBPJ 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU596189.1, BC046098.2 and BC015040.1. On Dec 18, 2003 this sequence version replaced NM_004882.2. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.53267.1, SRR1660803.196188.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGGAAAT CCTTCGCCAA CTTCATGTGC AAGAAAGACT TTCATCCTGC CTCCAAATCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_004873.3 |
CDS | 94..1446 |
Translation |
Target ORF information:
Target ORF information:
|
NM_004882.3 |
1 | ATGGGGAAAT CCTTCGCCAA CTTCATGTGC AAGAAAGACT TTCATCCTGC CTCCAAATCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Polymorphisms in cancer-related pathway genes and lung cancer. |
Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome. |
NKAP is a transcriptional repressor of notch signaling and is required for T cell development. |
Slug is a direct Notch target required for initiation of cardiac cushion cellularization. |
CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing. |