Gene Symbol | Cd300lb |
Entrez Gene ID | 217304 |
Full Name | CD300 molecule like family member B |
Synonyms | CLM-7,Clm7,Gm253,LMIR5 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Cd300lb cDNA ORF clone
Gene Symbol | Cd300lb |
Entrez Gene ID | 217304 |
Full Name | CD300 molecule like family member B |
Synonyms | CLM-7,Clm7,Gm253,LMIR5 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_199221.2 | NP_954691.2 | CMRF35-like molecule 7 isoform 1 |
NM_001347651.1 | NP_001334580.1 | CMRF35-like molecule 7 isoform 2 |
NM_199221.3 | NP_954691.3 | CMRF35-like molecule 7 isoform 1 precursor |
NM_001347651.2 | NP_001334580.1 | CMRF35-like molecule 7 isoform 2 |
Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock.
Voss OH, Murakami Y, Pena MY, Lee HN, Tian L, Margulies DH, Street JM, Yuen PS, Qi CF, Krzewski K, Coligan JE
Immunity44(6)1365-78(2016 06)
Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.
Voce DJ, Schmitt AM, Uppal A, McNerney ME, Bernal GM, Cahill KE, Wahlstrom JS, Nassiri A, Yu X, Crawley CD, White KP, Onel K, Weichselbaum RR, Yamini B
Oncogene34(21)2807-13(2015 May)
Campylobacter jejuni targets immunoglobulin-like receptor LMIR5.
Phongsisay V
Molecular immunology63(2)574-8(2015 Feb)
LMIR5 extracellular domain activates myeloid cells through toll-like receptor 4.
Phongsisay V, Iizasa E, Hara H, Yamasaki S
Molecular immunology62(1)169-77(2014 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
C. jejuni interacted preferentially with LMIR5.
Title: Campylobacter jejuni targets immunoglobulin-like receptor LMIR5.
LMIR5 extracellular domain is new inflammatory mediator and endogenous ligand of TLR4.
Title: LMIR5 extracellular domain activates myeloid cells through toll-like receptor 4.
neutrophil-derived soluble LMIR5 amplifies lipopolysaccharide-induced lethal inflammation.
Title: A soluble form of LMIR5/CD300b amplifies lipopolysaccharide-induced lethal inflammation in sepsis.
TIM1 is an endogenous ligand for LMIR5.
Title: TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury.
although both mouse and human LMIR5 play activatory roles in innate immunity cells, the functions of LMIR5 were differentially regulated in mouse versus human cells.
Title: Analysis of mouse LMIR5/CLM-7 as an activating receptor: differential regulation of LMIR5/CLM-7 in mouse versus human cells.
The following Cd300lb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd300lb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu09410 | |
Clone ID Related Accession (Same CDS sequence) | NM_199221.2 | |
Accession Version | NM_199221.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-28 | |
Organism | Mus musculus(house mouse) | |
Product | CMRF35-like molecule 7 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL607025.21, AY457053.1, AK169466.1 and AL669969.14. On Nov 7, 2005 this sequence version replaced NM_199221.1. ##Evidence-Data-START## Transcript exon combination :: AK170613.1, AK154359.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAGTAAGA CACTCAGAGG CAACCTGGAC AAACAGAACG AGTCAGCTGA GATCTCCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_954691.2 |
CDS | 1..768 |
Translation |
Target ORF information:
Target ORF information:
|
NM_199221.2 |
1 | ATGAGTAAGA CACTCAGAGG CAACCTGGAC AAACAGAACG AGTCAGCTGA GATCTCCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu46154 | |
Clone ID Related Accession (Same CDS sequence) | NM_001347651.1 , NM_001347651.2 | |
Accession Version | NM_001347651.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-29 | |
Organism | Mus musculus(house mouse) | |
Product | CMRF35-like molecule 7 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL607025.21, AK169466.1 and AL669969.14. On Dec 3, 2016 this sequence version replaced XM_006533072.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK169466.1, BC107352.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGATGC TCAGGCAAAA TGACACGGAC ACTTACTGGT GTGGTATTGA AAAGTTCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001334580.1 |
CDS | 185..544 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001347651.1 |
1 | ATGGAGATGC TCAGGCAAAA TGACACGGAC ACTTACTGGT GTGGTATTGA AAAGTTCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu46154 | |
Clone ID Related Accession (Same CDS sequence) | NM_001347651.1 , NM_001347651.2 | |
Accession Version | NM_001347651.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-31 | |
Organism | Mus musculus(house mouse) | |
Product | CMRF35-like molecule 7 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL607025.21 and AL669969.14. On Feb 27, 2019 this sequence version replaced NM_001347651.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK169466.1, SRR6230525.1050739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGATGC TCAGGCAAAA TGACACGGAC ACTTACTGGT GTGGTATTGA AAAGTTCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001334580.1 |
CDS | 170..529 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001347651.2 |
1 | ATGGAGATGC TCAGGCAAAA TGACACGGAC ACTTACTGGT GTGGTATTGA AAAGTTCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu84561 | |
Clone ID Related Accession (Same CDS sequence) | NM_199221.3 | |
Accession Version | NM_199221.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 630bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Mus musculus(house mouse) | |
Product | CMRF35-like molecule 7 isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL607025.21 and AL669969.14. On Feb 27, 2019 this sequence version replaced NM_199221.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR6230526.1836546.1, SRR6230526.1836544.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTGGCTGT CCCCAGCTTT GCTTCTTCTC AGTTTTCCAG GCTGCCTCTC CATCCAAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_954691.3 |
CDS | 124..753 |
Translation |
Target ORF information:
Target ORF information:
|
NM_199221.3 |
1 | ATGTGGCTGT CCCCAGCTTT GCTTCTTCTC AGTTTTCCAG GCTGCCTCTC CATCCAAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock. |
Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor. |
Campylobacter jejuni targets immunoglobulin-like receptor LMIR5. |
LMIR5 extracellular domain activates myeloid cells through toll-like receptor 4. |