Cela1 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Cela1 |
| Entrez Gene ID | 24331 |
| Full Name | chymotrypsin-like elastase family, member 1 |
| Synonyms | ELAI1,Ela1,RATELAI1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | catalyzes the hydrolysis of elastin and other proteins [RGD, Feb 2006]. |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_012552.4 | NP_036684.1 | chymotrypsin-like elastase family member 1 precursor |
| Homo sapiens (human) | CELA1 | NP_001962.3 |
| Canis lupus familiaris (dog) | CELA1 | NP_001003007.1 |
| Rattus norvegicus (Norway rat) | Cela1 | NP_036684.1 |
| Xenopus tropicalis (tropical clawed frog) | LOC496972 | NP_001011481.1 |
| Xenopus tropicalis (tropical clawed frog) | ela1 | NP_001025669.1 |
| LOC695507 | XP_001088682.1 | |
| Xenopus tropicalis (tropical clawed frog) | cela1 | NP_001011493.1 |
| Xenopus tropicalis (tropical clawed frog) | LOC101730694 | XP_004911959.1 |
| Xenopus tropicalis (tropical clawed frog) | cela1 | XP_002933738.2 |
| Pan troglodytes (chimpanzee) | CELA1 | XP_001142473.2 |
| Mus musculus (house mouse) | Cela1 | NP_291090.2 |
| Xenopus tropicalis (tropical clawed frog) | LOC100135144 | XP_002933737.2 |
| Bos taurus (cattle) | CELA1 | NP_776473.1 |
| Gallus gallus (chicken) | CELA1 | NP_001096672.1 |
Related articles in PubMed
Dynamic expression of chymotrypsin-like elastase 1 over the course of murine lung development.
Liu S, Young SM, Varisco BM
American journal of physiology. Lung cellular and molecular physiology306(12)L1104-16(2014 Jun)
Wnt/beta-catenin signaling is required for development of the exocrine pancreas.
Wells JM, Esni F, Boivin GP, Aronow BJ, Stuart W, Combs C, Sklenka A, Leach SD, Lowy AM
BMC developmental biology74(2007 Jan)
Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes.
Hinojos CA, Boerwinkle E, Fornage M, Doris PA
Hypertension (Dallas, Tex. : 1979)45(4)698-704(2005 Apr)
Electron-histochemical location of cathepsin D and elastase in the uterus.
Ryvnyak VV, Gudumak VS, Dulgieru OF
Bulletin of experimental biology and medicine136(2)199-201(2003 Aug)
Elastase involvement in extracellular and intracellular collagen degradation during postpartum involution of the uterus.
Ryvnyak VV, Dulgieru OF
Bulletin of experimental biology and medicine136(2)206-8(2003 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that both cathepsin D and elastase are present in lysosomes of smooth-muscle cells, macrophages, and fibroblasts of the myometrium.
Title: Electron-histochemical location of cathepsin D and elastase in the uterus.
Results describe the location of elastase in rat uterus during its postpartum involution.
Title: Elastase involvement in extracellular and intracellular collagen degradation during postpartum involution of the uterus.
The following Cela1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cela1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa12379 | |
| Clone ID Related Accession (Same CDS sequence) | NM_012552.4 | |
| Accession Version | NM_012552.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 801bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-29 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | chymotrypsin-like elastase family member 1 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07058908.1 and AABR07058907.1. On Apr 13, 2016 this sequence version replaced NM_012552.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: FQ227752.1, V01234.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689603 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCTGCGCT TCCTGGTGTT CGCTTCCCTG GTCCTGTATG GACACAGTAC CCAGGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_036684.1 |
| CDS | 23..823 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_012552.4 |
ORF Insert Sequence:
1 | ATGCTGCGCT TCCTGGTGTT CGCTTCCCTG GTCCTGTATG GACACAGTAC CCAGGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Dynamic expression of chymotrypsin-like elastase 1 over the course of murine lung development. |
|
Wnt/beta-catenin signaling is required for development of the exocrine pancreas. |
|
Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes. |
|
Electron-histochemical location of cathepsin D and elastase in the uterus. |
|
Elastase involvement in extracellular and intracellular collagen degradation during postpartum involution of the uterus. |