Gene Symbol | Abr |
Entrez Gene ID | 287537 |
Full Name | active BCR-related |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Abr cDNA ORF clone
Gene Symbol | Abr |
Entrez Gene ID | 287537 |
Full Name | active BCR-related |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001105814.2 | NP_001099284.1 | active breakpoint cluster region-related protein |
Homo sapiens (human) | ABR | NP_068781.2 |
Bos taurus (cattle) | ABR | NP_001039669.2 |
Mus musculus (house mouse) | Abr | NP_942598.1 |
Rattus norvegicus (Norway rat) | Abr | NP_001099284.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000865 | XP_316836.5 |
Gallus gallus (chicken) | LOC771897 | XP_004946703.1 |
Canis lupus familiaris (dog) | ABR | XP_537757.4 |
Drosophila melanogaster (fruit fly) | RhoGAP1A | NP_001096855.1 |
Xenopus tropicalis (tropical clawed frog) | abr | NP_001072313.1 |
Lack of bcr and abr promotes hypoxia-induced pulmonary hypertension in mice.
Yu M, Gong D, Lim M, Arutyunyan A, Groffen J, Heisterkamp N
PloS one7(11)e49756(2012)
Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.
Oh D, Han S, Seo J, Lee JR, Choi J, Groffen J, Kim K, Cho YS, Choi HS, Shin H, Woo J, Won H, Park SK, Kim SY, Jo J, Whitcomb DJ, Cho K, Kim H, Bae YC, Heisterkamp N, Choi SY, Kim E
The Journal of neuroscience : the official journal of the Society for Neuroscience30(42)14134-44(2010 Oct)
Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Bcr and Abr cooperate in negatively regulating acute inflammatory responses.
Cunnick JM, Schmidhuber S, Chen G, Yu M, Yi SJ, Cho YJ, Kaartinen V, Minoo P, Warburton D, Groffen J, Heisterkamp N
Molecular and cellular biology29(21)5742-50(2009 Nov)
Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.
Cho YJ, Cunnick JM, Yi SJ, Kaartinen V, Groffen J, Heisterkamp N
Molecular and cellular biology27(3)899-911(2007 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
breakpoint cluster region and ABR have novel roles in the regulation of synaptic Rac1 signaling, synaptic plasticity, and learning and memory, and that excessive Rac1 activity negatively affects synaptic and cognitive functions
Title: Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins.
The following Abr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa11468 | |
Clone ID Related Accession (Same CDS sequence) | NM_001105814.2 | |
Accession Version | NM_001105814.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2580bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | active breakpoint cluster region-related protein | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from FQ078152.1 and AABR07072152.1. On Jan 14, 2015 this sequence version replaced NM_001105814.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAGCCGC TTAGCCACCG GGGCCTGCCG CGCCTCTCTT GGATCGACAC CCTCTACAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001099284.1 |
CDS | 40..2619 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001105814.2 |
1 | ATGGAGCCGC TTAGCCACCG GGGCCTGCCG CGCCTCTCTT GGATCGACAC CCTCTACAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Lack of bcr and abr promotes hypoxia-induced pulmonary hypertension in mice. |
Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins. |
Defining the membrane proteome of NK cells. |
Bcr and Abr cooperate in negatively regulating acute inflammatory responses. |
Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages. |