Gene Symbol | Akap2 |
Entrez Gene ID | 298024 |
Full Name | A-kinase anchoring protein 2 |
Synonyms | AKAP-2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Akap2 cDNA ORF clone
gRNAs
Gene Symbol | Akap2 |
Entrez Gene ID | 298024 |
Full Name | A-kinase anchoring protein 2 |
Synonyms | AKAP-2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006238186.3 | XP_006238248.1 | A-kinase anchor protein 2 isoform X1 |
NM_001011974.2 | NP_001011974.2 | A-kinase anchor protein 2 isoform 2 |
NM_001309260.1 | NP_001296189.1 | A-kinase anchor protein 2 isoform 1 |
XM_006238185.3 | XP_006238247.1 | A-kinase anchor protein 2 isoform X1 |
Pan troglodytes (chimpanzee) | AKAP2 | XP_003951538.1 |
Mus musculus (house mouse) | Akap2 | NP_001030610.1 |
Gallus gallus (chicken) | AKAP2 | NP_001191146.1 |
Danio rerio (zebrafish) | akap2 | NP_001191129.1 |
Xenopus tropicalis (tropical clawed frog) | akap2 | NP_001123815.1 |
Homo sapiens (human) | AKAP2 | NP_001185585.1 |
Rattus norvegicus (Norway rat) | Akap2 | NP_001011974.1 |
A-kinase anchoring proteins: from protein complexes to physiology and disease.
Carnegie GK, Means CK, Scott JD
IUBMB life61(4)394-406(2009 Apr)
A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase.
Kinderman FS, Kim C, von Daake S, Ma Y, Pham BQ, Spraggon G, Xuong NH, Jennings PA, Taylor SS
Molecular cell24(3)397-408(2006 Nov)
Localized effects of cAMP mediated by distinct routes of protein kinase A.
Task?n K, Aandahl EM
Physiological reviews84(1)137-67(2004 Jan)
Molecular characterization of a cDNA that encodes six isoforms of a novel murine A kinase anchor protein.
Dong F, Feldmesser M, Casadevall A, Rubin CS
The Journal of biological chemistry273(11)6533-41(1998 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Akap2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Akap2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa28200 | |
Clone ID Related Accession (Same CDS sequence) | XM_006238186.3 , NM_001309260.1 , XM_006238185.3 | |
Accession Version | NM_001309260.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2652bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | A-kinase anchor protein 2 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC134204.3. On May 28, 2015 this sequence version replaced XM_006238184.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments and orthologous data. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAAATTG GGGTGTCCGT GGCAGAATGT AAAAGTGTAC CTGGAATCAC CTCTACCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001296189.1 |
CDS | 196..2847 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAAATTG GGGTGTCCGT GGCAGAATGT AAAAGTGTAC CTGGAATCAC CTCTACCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa45489 | |
Clone ID Related Accession (Same CDS sequence) | NM_001011974.2 | |
Accession Version | NM_001011974.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2613bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | A-kinase anchor protein 2 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC134204.3. On May 28, 2015 this sequence version replaced NM_001011974.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC085790.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAAATTG GGGTGTCCGT GGCAGAATGT AAAAGTGTAC CTGGAATCAC CTCTACCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001011974.2 |
CDS | 196..2808 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAAATTG GGGTGTCCGT GGCAGAATGT AAAAGTGTAC CTGGAATCAC CTCTACCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa28200 | |
Clone ID Related Accession (Same CDS sequence) | XM_006238186.3 , NM_001309260.1 , XM_006238185.3 | |
Accession Version | XM_006238186.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2652bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | A-kinase anchor protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238186.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAAATTG GGGTGTCCGT GGCAGAATGT AAAAGTGTAC CTGGAATCAC CTCTACCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006238248.1 |
CDS | 262..2913 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAAATTG GGGTGTCCGT GGCAGAATGT AAAAGTGTAC CTGGAATCAC CTCTACCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa28200 | |
Clone ID Related Accession (Same CDS sequence) | XM_006238186.3 , NM_001309260.1 , XM_006238185.3 | |
Accession Version | XM_006238185.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2652bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | A-kinase anchor protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238185.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAAATTG GGGTGTCCGT GGCAGAATGT AAAAGTGTAC CTGGAATCAC CTCTACCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006238247.1 |
CDS | 698..3349 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAAATTG GGGTGTCCGT GGCAGAATGT AAAAGTGTAC CTGGAATCAC CTCTACCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
A-kinase anchoring proteins: from protein complexes to physiology and disease. |
A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase. |
Localized effects of cAMP mediated by distinct routes of protein kinase A. |
Molecular characterization of a cDNA that encodes six isoforms of a novel murine A kinase anchor protein. |