Gene Symbol | Mettl21c |
Entrez Gene ID | 301378 |
Full Name | methyltransferase like 21C |
Synonyms | RGD1561425 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Mettl21c cDNA ORF clone
Gene Symbol | Mettl21c |
Entrez Gene ID | 301378 |
Full Name | methyltransferase like 21C |
Synonyms | RGD1561425 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001106908.1 | NP_001100378.1 | protein-lysine methyltransferase METTL21C |
XM_017596347.1 | XP_017451836.1 | protein-lysine methyltransferase METTL21C isoform X1 |
Homo sapiens (human) | METTL21C | NP_001010977.1 |
Bos taurus (cattle) | METTL21C | NP_001093853.1 |
Danio rerio (zebrafish) | LOC100149425 | XP_005168070.1 |
Xenopus tropicalis (tropical clawed frog) | mettl21c | XP_002933071.2 |
Canis lupus familiaris (dog) | METTL21C | XP_003639857.1 |
Danio rerio (zebrafish) | zgc:172067 | NP_001104718.1 |
Pan troglodytes (chimpanzee) | METTL21C | XP_001151722.1 |
Gallus gallus (chicken) | METTL21C | XP_416965.4 |
LOC701446 | XP_001094031.2 | |
Mus musculus (house mouse) | Mettl21c | NP_001013821.1 |
Rattus norvegicus (Norway rat) | Mettl21c | NP_001100378.1 |
METTL21C is a potential pleiotropic gene for osteoporosis and sarcopenia acting through the modulation of the NF-?B signaling pathway.
Huang J, Hsu YH, Mo C, Abreu E, Kiel DP, Bonewald LF, Brotto M, Karasik D
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research29(7)1531-1540(2014 Jul)
A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity.
Cloutier P, Lavall?e-Adam M, Faubert D, Blanchette M, Coulombe B
PLoS genetics9(1)e1003210(2013)
Lysine methylation of VCP by a member of a novel human protein methyltransferase family.
Kernstock S, Davydova E, Jakobsson M, Moen A, Pettersen S, M?landsmo GM, Egge-Jacobsen W, Falnes P?
Nature communications31038(2012)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Mettl21c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mettl21c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa02464 | |
Clone ID Related Accession (Same CDS sequence) | NM_001106908.1 , XM_017596347.1 | |
Accession Version | NM_001106908.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | protein-lysine methyltransferase METTL21C | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473965.2. On or before Oct 4, 2007 this sequence version replaced XM_217389.3, XM_001059953.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689600, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGATCAGC ATCTCCACAC GGCCCAGCAG CCCCTACGCT TGGGGACTCC ACAGGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001100378.1 |
CDS | 111..857 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001106908.1 |
1 | ATGGATCAGC ATCTCCACAC GGCCCAGCAG CCCCTACGCT TGGGGACTCC ACAGGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa02464 | |
Clone ID Related Accession (Same CDS sequence) | NM_001106908.1 , XM_017596347.1 | |
Accession Version | XM_017596347.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | protein-lysine methyltransferase METTL21C isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCAGC ATCTCCACAC GGCCCAGCAG CCCCTACGCT TGGGGACTCC ACAGGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017451836.1 |
CDS | 185..931 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017596347.1 |
1 | ATGGATCAGC ATCTCCACAC GGCCCAGCAG CCCCTACGCT TGGGGACTCC ACAGGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
METTL21C is a potential pleiotropic gene for osteoporosis and sarcopenia acting through the modulation of the NF-?B signaling pathway. |
A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. |
Lysine methylation of VCP by a member of a novel human protein methyltransferase family. |