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STX16 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol STX16
Entrez Gene ID 8675
Full Name syntaxin 16
Synonyms SYN16
General protein information
Preferred Names

syntaxin 16

Names

syntaxin-16

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

20

20q13.32

Summary This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1) gene. [provided by RefSeq, Mar 2011].
Disorder MIM:

603666

Disorder Html: Pseudohypoparathyroidism, type IB, 603233 (3)

mRNA and Protein(s)

mRNA Protein Name
NM_001134772.2 NP_001128244.1 syntaxin-16 isoform c
NM_001001433.2 NP_001001433.1 syntaxin-16 isoform a
NM_003763.5 NP_003754.2 syntaxin-16 isoform b
NM_001134773.2 NP_001128245.1 syntaxin-16 isoform d
NM_001204868.1 NP_001191797.1 syntaxin-16 isoform e



Bos taurus (cattle) STX16 XP_002692463.1
Danio rerio (zebrafish) stx16 XP_691316.2
Caenorhabditis elegans (roundworm) syn-16 NP_498105.1
Saccharomyces cerevisiae (baker's yeast) TLG2 NP_014624.1
Macaca mulatta (rhesus monkey) STX16 XP_002798124.1
Mus musculus (house mouse) Stx16 NP_766263.2
Homo sapiens (human) STX16 NP_001001433.1
Canis lupus familiaris (dog) STX16 XP_005635285.1
Arabidopsis thaliana (thale cress) SYP42 NP_567223.1
Drosophila melanogaster (fruit fly) Syx16 NP_523420.1
Magnaporthe oryzae (rice blast fungus) MGG_06883 XP_003709612.1
Pan troglodytes (chimpanzee) STX16 XP_514749.2
Rattus norvegicus (Norway rat) Stx16 NP_001102080.1
Gallus gallus (chicken) STX16 NP_001006295.1
Eremothecium gossypii AGOS_AEL026C NP_984835.2
Arabidopsis thaliana (thale cress) SYP41 NP_001031950.1
Xenopus tropicalis (tropical clawed frog) LOC100493473 XP_002943756.2
Anopheles gambiae (African malaria mosquito) AgaP_AGAP000850 XP_316820.5
Kluyveromyces lactis KLLA0A10681g XP_451467.1
Schizosaccharomyces pombe (fission yeast) tlg2 NP_593832.1
Neurospora crassa NCU04119 XP_961275.2
Arabidopsis thaliana (thale cress) SYP43 NP_566256.1


Related articles in PubMed

Growth hormone deficiency in monozygotic twins with autosomal dominant pseudohypoparathyroidism type Ib.
Sano S, Iwata H, Matsubara K, Fukami M, Kagami M, Ogata T
Endocrine journal62(6)523-9(2015)

Syntaxin 16 is a master recruitment factor for cytokinesis.
Neto H, Kaupisch A, Collins LL, Gould GW
Molecular biology of the cell24(23)3663-74(2013 Dec)

VAMP4 is required to maintain the ribbon structure of the Golgi apparatus.
Shitara A, Shibui T, Okayama M, Arakawa T, Mizoguchi I, Sakakura Y, Shakakura Y, Takuma T
Molecular and cellular biochemistry380(1-2)11-21(2013 Aug)

Syntaxin 16: unraveling cellular physiology through a ubiquitous SNARE molecule.
Chen Y, Gan BQ, Tang BL
Journal of cellular physiology225(2)326-32(2010 Nov)

Syntaxin 16 is enriched in neuronal dendrites and may have a role in neurite outgrowth.
Chua CE, Tang BL
Molecular membrane biology25(1)35-45(2008 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

STX16 microdeletion was identified in male monozygotic twins (with pseudohypoparathyroidism type 1B leading to growth hormone deficiency) and mother/grandmother (not father/grandfather or sister [their triplet with separate placenta]). [CASE STUDY]
Title: Growth hormone deficiency in monozygotic twins with autosomal dominant pseudohypoparathyroidism type Ib.

syntaxin 16 is a key regulator of cytokinesis.
Title: Syntaxin 16 is a master recruitment factor for cytokinesis.

Data indicate that depletion of VAMP4, syntaxin 6, syntaxin 16, and Vti1a disrupted the Golgi ribbon structure.
Title: VAMP4 is required to maintain the ribbon structure of the Golgi apparatus.

A patient with familial pseudohypoparathyroidism type Ib and his asymptomatic brother were found to have methylation defect at GNAS (guanine nucleotide-binding protein G) and microdeletion involving exons 4-6 of neighboring gene STX16. [CASE REPORT]
Title: Neuromuscular symptoms in a patient with familial pseudohypoparathyroidism type Ib diagnosed by methylation-specific multiplex ligation-dependent probe amplification.

De novo 3-kb STX16 deletions, reported only once previously, are infrequent but should be excluded in all cases of Pseudohypoparathyroidism-Ib, even when the family history is negative for an inherited form of this disorder.
Title: De novo STX16 deletions: an infrequent cause of pseudohypoparathyroidism type Ib that should be excluded in sporadic cases.

The following STX16 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STX16 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu00273 NM_001204868.1
Latest version!
Homo sapiens syntaxin 16 (STX16), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu10405 NM_003763.5
Latest version!
Homo sapiens syntaxin 16 (STX16), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$154.50-$216.30
$309.00
OHu12209 NM_001134772.2
Latest version!
Homo sapiens syntaxin 16 (STX16), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$154.50-$216.30
$309.00
OHu10789 NM_001134773.2
Latest version!
Homo sapiens syntaxin 16 (STX16), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $216.30
$309.00
OHu20582 NM_001001433.2
Latest version!
Homo sapiens syntaxin 16 (STX16), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $216.30
$309.00

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2-4 Clone 40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu00273
Clone ID Related Accession (Same CDS sequence) NM_001204868.1
Accession Version NM_001204868.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 819bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-23
Organism Homo sapiens(Human)
Product syntaxin-16 isoform e
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK316547.1, BX396221.2, AL050327.6, BC019042.2, AK026974.1, CA427122.1, AL139349.37 and AA256337.1. Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream start codon, compared to variant 1. The encoded isoform (e) is shorter at the N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX396221.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCACTGG TGTCAGGCAT CAGCTTAGAT CCAGAAGCAG CGATTGGTGT GACAAAACGG 
CCACCTCCTA AGTGGGTGGA TGGAGTGGAT GAAATTCAGT ATGATGTTGG CCGGATTAAG
CAGAAGATGA AAGAATTGGC CAGCCTTCAT GACAAGCATT TAAACAGACC CACCCTGGAT
GACAGCAGCG AAGAGGAACA TGCCATTGAG ATAACTACCC AAGAGATCAC TCAGCTCTTC
CACAGGTGCC AGCGTGCCGT GCAGGCCCTG CCGAGCCGGG CCCGGGCCTG CTCCGAGCAG
GAGGGGCGGC TGCTTGGGAA CGTGGTGGCC TCGCTGGCGC AGGCCCTGCA GGAACTCTCC
ACCAGCTTCC GGCACGCACA GTCAGGCTAC CTCAAACGCA TGAAGAATCG AGAGGAAAGA
TCCCAGCATT TTTTCGACAC ATCAGTACCA CTAATGGATG ATGGAGACGA TAACACTCTT
TACCATCGGG GTTTTACAGA GGACCAGTTA GTTCTGGTGG AGCAGAACAC ACTGATGGTG
GAAGAGCGGG AACGAGAGAT TCGCCAGATT GTACAGTCCA TTTCTGACCT GAATGAAATA
TTCAGGGACT TAGGGGCGAT GATTGTAGAA CAGGGTACAG TCCTTGACAG AATTGACTAT
AACGTTGAAC AGTCCTGTAT CAAAACTGAA GATGGTTTGA AACAGCTTCA CAAGGCAGAA
CAGTATCAAA AGAAGAATCG GAAGATGCTT GTGATTTTAA TATTATTTGT CATCATCATT
GTGCTCATTG TTGTCCTCGT TGGCGTGAAG TCTCGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001191797.1
CDS276..1094
Misc Feature(1)360..680
Misc Feature(2)813..989
Misc Feature(3)order(816..818,822..827,831..848,852..860,864..869,873..881,885..890,894..902,906..911,915..932,936..953,957..974,978..986)
Misc Feature(4)906..908
Exon (1)1..182
Exon (2)183..248
Exon (3)249..260
Exon (4)261..368
Exon (5)369..509
Exon (6)510..672
Exon (7)673..764
Exon (8)765..908
Exon (9)909..989
Exon (10)990..4329
Translation

Target ORF information:

RefSeq Version NM_001204868.1
Organism Homo sapiens(Human)
Definition Homo sapiens syntaxin 16 (STX16), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001204868.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCACTGG TGTCAGGCAT CAGCTTAGAT CCAGAAGCAG CGATTGGTGT GACAAAACGG 
CCACCTCCTA AGTGGGTGGA TGGAGTGGAT GAAATTCAGT ATGATGTTGG CCGGATTAAG
CAGAAGATGA AAGAATTGGC CAGCCTTCAT GACAAGCATT TAAACAGACC CACCCTGGAT
GACAGCAGCG AAGAGGAACA TGCCATTGAG ATAACTACCC AAGAGATCAC TCAGCTCTTC
CACAGGTGCC AGCGTGCCGT GCAGGCCCTG CCGAGCCGGG CCCGGGCCTG CTCCGAGCAG
GAGGGGCGGC TGCTTGGGAA CGTGGTGGCC TCGCTGGCGC AGGCCCTGCA GGAACTCTCC
ACCAGCTTCC GGCACGCACA GTCAGGCTAC CTCAAACGCA TGAAGAATCG AGAGGAAAGA
TCCCAGCATT TTTTCGACAC ATCAGTACCA CTAATGGATG ATGGAGACGA TAACACTCTT
TACCATCGGG GTTTTACAGA GGACCAGTTA GTTCTGGTGG AGCAGAACAC ACTGATGGTG
GAAGAGCGGG AACGAGAGAT TCGCCAGATT GTACAGTCCA TTTCTGACCT GAATGAAATA
TTCAGGGACT TAGGGGCGAT GATTGTAGAA CAGGGTACAG TCCTTGACAG AATTGACTAT
AACGTTGAAC AGTCCTGTAT CAAAACTGAA GATGGTTTGA AACAGCTTCA CAAGGCAGAA
CAGTATCAAA AGAAGAATCG GAAGATGCTT GTGATTTTAA TATTATTTGT CATCATCATT
GTGCTCATTG TTGTCCTCGT TGGCGTGAAG TCTCGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10405
Clone ID Related Accession (Same CDS sequence) NM_003763.5
Accession Version NM_003763.5 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 915bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-23
Organism Homo sapiens(Human)
Product syntaxin-16 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC424825.1, BU844980.1, BC019042.2, AK026974.1, CA427122.1, AL139349.37 and AA256337.1. On Mar 10, 2011 this sequence version replaced NM_003763.4. Transcript Variant: This variant (2) uses an alternate in-frame splice site and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in a shorter isoform (b, also referred to as isoform A), compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC019042.2, AF008935.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCACCA GGCGTTTAAC CGACGCTTTC TTGTTGTTGC GGAATAATTC CATCCAAAAC 
CGGCAGCTGT TAGCCGAGCA ACTTGCTGAT GACCGTATGG CACTGGTGTC AGGCATCAGC
TTAGATCCAG AAGCAGCGAT TGGTGTGACA AAACGGCCAC CTCCTAAGTG GGTGGATGGA
GTGGATGAAA TTCAGTATGA TGTTGGCCGG ATTAAGCAGA AGATGAAAGA ATTGGCCAGC
CTTCATGACA AGCATTTAAA CAGACCCACC CTGGATGACA GCAGCGAAGA GGAACATGCC
ATTGAGATAA CTACCCAAGA GATCACTCAG CTCTTCCACA GGTGCCAGCG TGCCGTGCAG
GCCCTGCCGA GCCGGGCCCG GGCCTGCTCC GAGCAGGAGG GGCGGCTGCT TGGGAACGTG
GTGGCCTCGC TGGCGCAGGC CCTGCAGGAA CTCTCCACCA GCTTCCGGCA CGCACAGTCA
GGCTACCTCA AACGCATGAA GAATCGAGAG GAAAGATCCC AGCATTTTTT CGACACATCA
GTACCACTAA TGGATGATGG AGACGATAAC ACTCTTTACC ATCGGGGTTT TACAGAGGAC
CAGTTAGTTC TGGTGGAGCA GAACACACTG ATGGTGGAAG AGCGGGAACG AGAGATTCGC
CAGATTGTAC AGTCCATTTC TGACCTGAAT GAAATATTCA GGGACTTAGG GGCGATGATT
GTAGAACAGG GTACAGTCCT TGACAGAATT GACTATAACG TTGAACAGTC CTGTATCAAA
ACTGAAGATG GTTTGAAACA GCTTCACAAG GCAGAACAGT ATCAAAAGAA GAATCGGAAG
ATGCTTGTGA TTTTAATATT ATTTGTCATC ATCATTGTGC TCATTGTTGT CCTCGTTGGC
GTGAAGTCTC GATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_003754.2
CDS755..1669
Misc Feature(1)749..751
Misc Feature(2)914..1594
Misc Feature(3)1388..1564
Misc Feature(4)order(1391..1393,1397..1402,1406..1423,1427..1435,1439..1444,1448..1456,1460..1465,1469..1477,1481..1486,1490..1507,1511..1528,1532..1549,1553..1561)
Misc Feature(5)1481..1483
Exon (1)1..835
Exon (2)836..943
Exon (3)944..1084
Exon (4)1085..1247
Exon (5)1248..1339
Exon (6)1340..1483
Exon (7)1484..1564
Exon (8)1565..4904
Translation

Target ORF information:

RefSeq Version NM_003763.5
Organism Homo sapiens(Human)
Definition Homo sapiens syntaxin 16 (STX16), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003763.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCACCA GGCGTTTAAC CGACGCTTTC TTGTTGTTGC GGAATAATTC CATCCAAAAC 
CGGCAGCTGT TAGCCGAGCA ACTTGCTGAT GACCGTATGG CACTGGTGTC AGGCATCAGC
TTAGATCCAG AAGCAGCGAT TGGTGTGACA AAACGGCCAC CTCCTAAGTG GGTGGATGGA
GTGGATGAAA TTCAGTATGA TGTTGGCCGG ATTAAGCAGA AGATGAAAGA ATTGGCCAGC
CTTCATGACA AGCATTTAAA CAGACCCACC CTGGATGACA GCAGCGAAGA GGAACATGCC
ATTGAGATAA CTACCCAAGA GATCACTCAG CTCTTCCACA GGTGCCAGCG TGCCGTGCAG
GCCCTGCCGA GCCGGGCCCG GGCCTGCTCC GAGCAGGAGG GGCGGCTGCT TGGGAACGTG
GTGGCCTCGC TGGCGCAGGC CCTGCAGGAA CTCTCCACCA GCTTCCGGCA CGCACAGTCA
GGCTACCTCA AACGCATGAA GAATCGAGAG GAAAGATCCC AGCATTTTTT CGACACATCA
GTACCACTAA TGGATGATGG AGACGATAAC ACTCTTTACC ATCGGGGTTT TACAGAGGAC
CAGTTAGTTC TGGTGGAGCA GAACACACTG ATGGTGGAAG AGCGGGAACG AGAGATTCGC
CAGATTGTAC AGTCCATTTC TGACCTGAAT GAAATATTCA GGGACTTAGG GGCGATGATT
GTAGAACAGG GTACAGTCCT TGACAGAATT GACTATAACG TTGAACAGTC CTGTATCAAA
ACTGAAGATG GTTTGAAACA GCTTCACAAG GCAGAACAGT ATCAAAAGAA GAATCGGAAG
ATGCTTGTGA TTTTAATATT ATTTGTCATC ATCATTGTGC TCATTGTTGT CCTCGTTGGC
GTGAAGTCTC GATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu12209
Clone ID Related Accession (Same CDS sequence) NM_001134772.2
Accession Version NM_001134772.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 966bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-23
Organism Homo sapiens(Human)
Product syntaxin-16 isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC424825.1, BU844980.1, BC073876.1, AK026974.1, CA427122.1, AL139349.37 and AA256337.1. On Mar 10, 2011 this sequence version replaced NM_001134772.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in a shorter isoform (c), compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC073876.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCCACCA GGCGTTTAAC CGACGCTTTC TTGTTGTTGC GGAATAATTC CATCCAAAAC 
CGGCAGCTGT TAGCCGAGCA AGTGAGTAGT CACATCACCT CCAGCCCTCT GCATTCACGT
AGCATTGCTG CGCTTGCTGA TGACCGTATG GCACTGGTGT CAGGCATCAG CTTAGATCCA
GAAGCAGCGA TTGGTGTGAC AAAACGGCCA CCTCCTAAGT GGGTGGATGG AGTGGATGAA
ATTCAGTATG ATGTTGGCCG GATTAAGCAG AAGATGAAAG AATTGGCCAG CCTTCATGAC
AAGCATTTAA ACAGACCCAC CCTGGATGAC AGCAGCGAAG AGGAACATGC CATTGAGATA
ACTACCCAAG AGATCACTCA GCTCTTCCAC AGGTGCCAGC GTGCCGTGCA GGCCCTGCCG
AGCCGGGCCC GGGCCTGCTC CGAGCAGGAG GGGCGGCTGC TTGGGAACGT GGTGGCCTCG
CTGGCGCAGG CCCTGCAGGA ACTCTCCACC AGCTTCCGGC ACGCACAGTC AGGCTACCTC
AAACGCATGA AGAATCGAGA GGAAAGATCC CAGCATTTTT TCGACACATC AGTACCACTA
ATGGATGATG GAGACGATAA CACTCTTTAC CATCGGGGTT TTACAGAGGA CCAGTTAGTT
CTGGTGGAGC AGAACACACT GATGGTGGAA GAGCGGGAAC GAGAGATTCG CCAGATTGTA
CAGTCCATTT CTGACCTGAA TGAAATATTC AGGGACTTAG GGGCGATGAT TGTAGAACAG
GGTACAGTCC TTGACAGAAT TGACTATAAC GTTGAACAGT CCTGTATCAA AACTGAAGAT
GGTTTGAAAC AGCTTCACAA GGCAGAACAG TATCAAAAGA AGAATCGGAA GATGCTTGTG
ATTTTAATAT TATTTGTCAT CATCATTGTG CTCATTGTTG TCCTCGTTGG CGTGAAGTCT
CGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001128244.1
CDS755..1720
Misc Feature(1)749..751
Misc Feature(2)875..877
Misc Feature(3)965..1645
Misc Feature(4)1439..1615
Misc Feature(5)order(1442..1444,1448..1453,1457..1474,1478..1486,1490..1495,1499..1507,1511..1516,1520..1528,1532..1537,1541..1558,1562..1579,1583..1600,1604..1612)
Misc Feature(6)1532..1534
Misc Feature(7)1646..1708
Exon (1)1..886
Exon (2)887..994
Exon (3)995..1135
Exon (4)1136..1298
Exon (5)1299..1390
Exon (6)1391..1534
Exon (7)1535..1615
Exon (8)1616..4955
Translation

Target ORF information:

RefSeq Version NM_001134772.2
Organism Homo sapiens(Human)
Definition Homo sapiens syntaxin 16 (STX16), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001134772.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCCACCA GGCGTTTAAC CGACGCTTTC TTGTTGTTGC GGAATAATTC CATCCAAAAC 
CGGCAGCTGT TAGCCGAGCA AGTGAGTAGT CACATCACCT CCAGCCCTCT GCATTCACGT
AGCATTGCTG CGCTTGCTGA TGACCGTATG GCACTGGTGT CAGGCATCAG CTTAGATCCA
GAAGCAGCGA TTGGTGTGAC AAAACGGCCA CCTCCTAAGT GGGTGGATGG AGTGGATGAA
ATTCAGTATG ATGTTGGCCG GATTAAGCAG AAGATGAAAG AATTGGCCAG CCTTCATGAC
AAGCATTTAA ACAGACCCAC CCTGGATGAC AGCAGCGAAG AGGAACATGC CATTGAGATA
ACTACCCAAG AGATCACTCA GCTCTTCCAC AGGTGCCAGC GTGCCGTGCA GGCCCTGCCG
AGCCGGGCCC GGGCCTGCTC CGAGCAGGAG GGGCGGCTGC TTGGGAACGT GGTGGCCTCG
CTGGCGCAGG CCCTGCAGGA ACTCTCCACC AGCTTCCGGC ACGCACAGTC AGGCTACCTC
AAACGCATGA AGAATCGAGA GGAAAGATCC CAGCATTTTT TCGACACATC AGTACCACTA
ATGGATGATG GAGACGATAA CACTCTTTAC CATCGGGGTT TTACAGAGGA CCAGTTAGTT
CTGGTGGAGC AGAACACACT GATGGTGGAA GAGCGGGAAC GAGAGATTCG CCAGATTGTA
CAGTCCATTT CTGACCTGAA TGAAATATTC AGGGACTTAG GGGCGATGAT TGTAGAACAG
GGTACAGTCC TTGACAGAAT TGACTATAAC GTTGAACAGT CCTGTATCAA AACTGAAGAT
GGTTTGAAAC AGCTTCACAA GGCAGAACAG TATCAAAAGA AGAATCGGAA GATGCTTGTG
ATTTTAATAT TATTTGTCAT CATCATTGTG CTCATTGTTG TCCTCGTTGG CGTGAAGTCT
CGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10789
Clone ID Related Accession (Same CDS sequence) NM_001134773.2
Accession Version NM_001134773.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 927bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-23
Organism Homo sapiens(Human)
Product syntaxin-16 isoform d
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC424825.1, BU844980.1, BU844520.1, AL139349.37, BC019042.2, AK026974.1, CA427122.1 and AA256337.1. On Mar 10, 2011 this sequence version replaced NM_001134773.1. Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a shorter isoform (d), compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF038897.1, BU844520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCACCA GGCGTTTAAC CGACGCTTTC TTGTTGTTGC GGAATAATTC CATCCAAAAC 
CGGCAGCTGT TAGCCGAGCA AGAGCTGGAC GAGCTTGCTG ATGACCGTAT GGCACTGGTG
TCAGGCATCA GCTTAGATCC AGAAGCAGCG ATTGGTGTGA CAAAACGGCC ACCTCCTAAG
TGGGTGGATG GAGTGGATGA AATTCAGTAT GATGTTGGCC GGATTAAGCA GAAGATGAAA
GAATTGGCCA GCCTTCATGA CAAGCATTTA AACAGACCCA CCCTGGATGA CAGCAGCGAA
GAGGAACATG CCATTGAGAT AACTACCCAA GAGATCACTC AGCTCTTCCA CAGGTGCCAG
CGTGCCGTGC AGGCCCTGCC GAGCCGGGCC CGGGCCTGCT CCGAGCAGGA GGGGCGGCTG
CTTGGGAACG TGGTGGCCTC GCTGGCGCAG GCCCTGCAGG AACTCTCCAC CAGCTTCCGG
CACGCACAGT CAGGCTACCT CAAACGCATG AAGAATCGAG AGGAAAGATC CCAGCATTTT
TTCGACACAT CAGTACCACT AATGGATGAT GGAGACGATA ACACTCTTTA CCATCGGGGT
TTTACAGAGG ACCAGTTAGT TCTGGTGGAG CAGAACACAC TGATGGTGGA AGAGCGGGAA
CGAGAGATTC GCCAGATTGT ACAGTCCATT TCTGACCTGA ATGAAATATT CAGGGACTTA
GGGGCGATGA TTGTAGAACA GGGTACAGTC CTTGACAGAA TTGACTATAA CGTTGAACAG
TCCTGTATCA AAACTGAAGA TGGTTTGAAA CAGCTTCACA AGGCAGAACA GTATCAAAAG
AAGAATCGGA AGATGCTTGT GATTTTAATA TTATTTGTCA TCATCATTGT GCTCATTGTT
GTCCTCGTTG GCGTGAAGTC TCGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001128245.1
CDS755..1681
Misc Feature(1)749..751
Misc Feature(2)926..1606
Misc Feature(3)1400..1576
Misc Feature(4)order(1403..1405,1409..1414,1418..1435,1439..1447,1451..1456,1460..1468,1472..1477,1481..1489,1493..1498,1502..1519,1523..1540,1544..1561,1565..1573)
Misc Feature(5)1493..1495
Exon (1)1..835
Exon (2)836..847
Exon (3)848..955
Exon (4)956..1096
Exon (5)1097..1259
Exon (6)1260..1351
Exon (7)1352..1495
Exon (8)1496..1576
Exon (9)1577..4916
Translation

Target ORF information:

RefSeq Version NM_001134773.2
Organism Homo sapiens(Human)
Definition Homo sapiens syntaxin 16 (STX16), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001134773.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCACCA GGCGTTTAAC CGACGCTTTC TTGTTGTTGC GGAATAATTC CATCCAAAAC 
CGGCAGCTGT TAGCCGAGCA AGAGCTGGAC GAGCTTGCTG ATGACCGTAT GGCACTGGTG
TCAGGCATCA GCTTAGATCC AGAAGCAGCG ATTGGTGTGA CAAAACGGCC ACCTCCTAAG
TGGGTGGATG GAGTGGATGA AATTCAGTAT GATGTTGGCC GGATTAAGCA GAAGATGAAA
GAATTGGCCA GCCTTCATGA CAAGCATTTA AACAGACCCA CCCTGGATGA CAGCAGCGAA
GAGGAACATG CCATTGAGAT AACTACCCAA GAGATCACTC AGCTCTTCCA CAGGTGCCAG
CGTGCCGTGC AGGCCCTGCC GAGCCGGGCC CGGGCCTGCT CCGAGCAGGA GGGGCGGCTG
CTTGGGAACG TGGTGGCCTC GCTGGCGCAG GCCCTGCAGG AACTCTCCAC CAGCTTCCGG
CACGCACAGT CAGGCTACCT CAAACGCATG AAGAATCGAG AGGAAAGATC CCAGCATTTT
TTCGACACAT CAGTACCACT AATGGATGAT GGAGACGATA ACACTCTTTA CCATCGGGGT
TTTACAGAGG ACCAGTTAGT TCTGGTGGAG CAGAACACAC TGATGGTGGA AGAGCGGGAA
CGAGAGATTC GCCAGATTGT ACAGTCCATT TCTGACCTGA ATGAAATATT CAGGGACTTA
GGGGCGATGA TTGTAGAACA GGGTACAGTC CTTGACAGAA TTGACTATAA CGTTGAACAG
TCCTGTATCA AAACTGAAGA TGGTTTGAAA CAGCTTCACA AGGCAGAACA GTATCAAAAG
AAGAATCGGA AGATGCTTGT GATTTTAATA TTATTTGTCA TCATCATTGT GCTCATTGTT
GTCCTCGTTG GCGTGAAGTC TCGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20582
Clone ID Related Accession (Same CDS sequence) NM_001001433.2
Accession Version NM_001001433.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 978bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-23
Organism Homo sapiens(Human)
Product syntaxin-16 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC424825.1, BU844980.1, AK026970.1, AL139349.37, CA427122.1 and AA256337.1. This sequence is a reference standard in the RefSeqGene project. On Mar 10, 2011 this sequence version replaced NM_001001433.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also referred to as isoform B). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK026970.1, AF008936.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCCACCA GGCGTTTAAC CGACGCTTTC TTGTTGTTGC GGAATAATTC CATCCAAAAC 
CGGCAGCTGT TAGCCGAGCA AGTGAGTAGT CACATCACCT CCAGCCCTCT GCATTCACGT
AGCATTGCTG CGGAGCTGGA CGAGCTTGCT GATGACCGTA TGGCACTGGT GTCAGGCATC
AGCTTAGATC CAGAAGCAGC GATTGGTGTG ACAAAACGGC CACCTCCTAA GTGGGTGGAT
GGAGTGGATG AAATTCAGTA TGATGTTGGC CGGATTAAGC AGAAGATGAA AGAATTGGCC
AGCCTTCATG ACAAGCATTT AAACAGACCC ACCCTGGATG ACAGCAGCGA AGAGGAACAT
GCCATTGAGA TAACTACCCA AGAGATCACT CAGCTCTTCC ACAGGTGCCA GCGTGCCGTG
CAGGCCCTGC CGAGCCGGGC CCGGGCCTGC TCCGAGCAGG AGGGGCGGCT GCTTGGGAAC
GTGGTGGCCT CGCTGGCGCA GGCCCTGCAG GAACTCTCCA CCAGCTTCCG GCACGCACAG
TCAGGCTACC TCAAACGCAT GAAGAATCGA GAGGAAAGAT CCCAGCATTT TTTCGACACA
TCAGTACCAC TAATGGATGA TGGAGACGAT AACACTCTTT ACCATCGGGG TTTTACAGAG
GACCAGTTAG TTCTGGTGGA GCAGAACACA CTGATGGTGG AAGAGCGGGA ACGAGAGATT
CGCCAGATTG TACAGTCCAT TTCTGACCTG AATGAAATAT TCAGGGACTT AGGGGCGATG
ATTGTAGAAC AGGGTACAGT CCTTGACAGA ATTGACTATA ACGTTGAACA GTCCTGTATC
AAAACTGAAG ATGGTTTGAA ACAGCTTCAC AAGGCAGAAC AGTATCAAAA GAAGAATCGG
AAGATGCTTG TGATTTTAAT ATTATTTGTC ATCATCATTG TGCTCATTGT TGTCCTCGTT
GGCGTGAAGT CTCGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001001433.1
CDS755..1732
Misc Feature(1)749..751
Misc Feature(2)875..877
Misc Feature(3)977..1657
Misc Feature(4)1451..1627
Misc Feature(5)order(1454..1456,1460..1465,1469..1486,1490..1498,1502..1507,1511..1519,1523..1528,1532..1540,1544..1549,1553..1570,1574..1591,1595..1612,1616..1624)
Misc Feature(6)1544..1546
Misc Feature(7)1658..1720
Exon (1)1..886
Exon (2)887..898
Exon (3)899..1006
Exon (4)1007..1147
Exon (5)1148..1310
Exon (6)1311..1402
Exon (7)1403..1546
Exon (8)1547..1627
Exon (9)1628..4967
Translation

Target ORF information:

RefSeq Version NM_001001433.2
Organism Homo sapiens(Human)
Definition Homo sapiens syntaxin 16 (STX16), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001001433.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGCCACCA GGCGTTTAAC CGACGCTTTC TTGTTGTTGC GGAATAATTC CATCCAAAAC 
CGGCAGCTGT TAGCCGAGCA AGTGAGTAGT CACATCACCT CCAGCCCTCT GCATTCACGT
AGCATTGCTG CGGAGCTGGA CGAGCTTGCT GATGACCGTA TGGCACTGGT GTCAGGCATC
AGCTTAGATC CAGAAGCAGC GATTGGTGTG ACAAAACGGC CACCTCCTAA GTGGGTGGAT
GGAGTGGATG AAATTCAGTA TGATGTTGGC CGGATTAAGC AGAAGATGAA AGAATTGGCC
AGCCTTCATG ACAAGCATTT AAACAGACCC ACCCTGGATG ACAGCAGCGA AGAGGAACAT
GCCATTGAGA TAACTACCCA AGAGATCACT CAGCTCTTCC ACAGGTGCCA GCGTGCCGTG
CAGGCCCTGC CGAGCCGGGC CCGGGCCTGC TCCGAGCAGG AGGGGCGGCT GCTTGGGAAC
GTGGTGGCCT CGCTGGCGCA GGCCCTGCAG GAACTCTCCA CCAGCTTCCG GCACGCACAG
TCAGGCTACC TCAAACGCAT GAAGAATCGA GAGGAAAGAT CCCAGCATTT TTTCGACACA
TCAGTACCAC TAATGGATGA TGGAGACGAT AACACTCTTT ACCATCGGGG TTTTACAGAG
GACCAGTTAG TTCTGGTGGA GCAGAACACA CTGATGGTGG AAGAGCGGGA ACGAGAGATT
CGCCAGATTG TACAGTCCAT TTCTGACCTG AATGAAATAT TCAGGGACTT AGGGGCGATG
ATTGTAGAAC AGGGTACAGT CCTTGACAGA ATTGACTATA ACGTTGAACA GTCCTGTATC
AAAACTGAAG ATGGTTTGAA ACAGCTTCAC AAGGCAGAAC AGTATCAAAA GAAGAATCGG
AAGATGCTTG TGATTTTAAT ATTATTTGTC ATCATCATTG TGCTCATTGT TGTCCTCGTT
GGCGTGAAGT CTCGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Growth hormone deficiency in monozygotic twins with autosomal dominant pseudohypoparathyroidism type Ib.
Endocrine journal62(6)523-9(2015)
Sano S,Iwata H,Matsubara K,Fukami M,Kagami M,Ogata T


book

Syntaxin 16 is a master recruitment factor for cytokinesis.
Molecular biology of the cell24(23)3663-74(2013 Dec)
Neto H,Kaupisch A,Collins LL,Gould GW


book

VAMP4 is required to maintain the ribbon structure of the Golgi apparatus.
Molecular and cellular biochemistry380(1-2)11-21(2013 Aug)
Shitara A,Shibui T,Okayama M,Arakawa T,Mizoguchi I,Sakakura Y,Shakakura Y,Takuma T


book

Syntaxin 16: unraveling cellular physiology through a ubiquitous SNARE molecule.
Journal of cellular physiology225(2)326-32(2010 Nov)
Chen Y,Gan BQ,Tang BL


book

Syntaxin 16 is enriched in neuronal dendrites and may have a role in neurite outgrowth.
Molecular membrane biology25(1)35-45(2008 Jan)
Chua CE,Tang BL


 
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